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Saturday, 11 January 2014

Food Therapy - Strawberries and leukaemia (CEM)

Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits.
Leukemia is defined as condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system. Depending to the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.



Nutrients and Chemicals constituents

1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc. 

The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin 
The benefits
Intake of certain amounts of berry fruits, including strawberries, has been suggested to have beneficial effects against oxidative stress mediated diseases. The methanolic extract of strawberry (MESB) fruits are found to inhibit the  tumor cell proliferation by activating apoptosis with no side effects in a time-dependent manner and resulted in extended life span. Other in the study of flavonoids from strawberry 'Nohime', showed the effect of these flavonoids on the degranulation in RBL-2H3 cells. due to suppression of [Ca(2+)]i elevation and Syk activation.


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The Side effects
1. Some people may beexperience anaphylactoid reaction to the consumption of strawberries


2. Oxalation
Oxalates in high concentration can cause problem for people with kidney diseases.
3. Etc. 
 
References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC.(PubMed)
(2) Inhibitory effects of flavonoids isolated from Fragaria ananassa Duch on IgE-mediated degranulation in rat basophilic leukemia RBL-2H3.by Itoh T, Ninomiya M, Yasuda M, Koshikawa K, Deyashiki Y, Nozawa Y, Akao Y, Koketsu M.(PubMed)