Alzheimer's disease (AD) is a neurodegenerative disease correlated with major reductions of neurons to the respective target areas, named after German physician Alois Alzheimer.
Alzheimer's destroys brain cells, causing cognitive modalities severe enough to affect language communication, memory, lifelong hobbies or social life. Alzheimer's gets worse over time, and it is fatal.
On finding a potential compound for the treatment of Alzheimer's disease, researchers investigated the ability of bromelain, a plant cysteine protease derived from pineapple stems interaction with synthetic Aβ42 monomers and oligomers.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Bromelain Degrades Aβ1-42 Monomers and Soluble Aggregates: An In Vitro Study in Cerebrospinal Fluid of Alzheimer's Disease Patients by Sancesario GM1, Nuccetelli M2, Cerri A3, Zegeer J2, Severini C4, Ciotti MT5, Pieri M2, Martorana A3, Caltagirone C1,3, Nistico R5,6, Bernardini S. (PubMed)
(2) Alpha 2-macroglobulin-mediated degradation of amyloid beta 1--42: a mechanism to enhance amyloid beta catabolism by Lauer D1, Reichenbach A, Birkenmeier G. (PubMed)
(3) High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 mice by Peter Thériault,1 Ayman ElAli,2 and Serge Rivest. (PMC)