Thursday, 20 September 2018

Yoga May Be Considered as Secondary Intervention for Heart Disease, Scientists Suggest

By Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Yoga intervention may be the new way to improve over all conditions in prevented onset of heart disease, some researchers suggested.

Heart diseases are  a class of disease characterized by a wide range of conditions, caused by coronary artery disease; heart rhythm problems (arrhythmias); and heart defects......

Although used interchangeable with cardiovascular diseases which are only expressed  conditions involved narrowed or blocked blood vessels that can lead to a heart attack, chest pain (angina) or stroke.

According to statistic, in US, heart disease is a leading cause of death in women and men. Approximately, 600,000 Americans die from heart disease every year, representing 1 in every 4 deaths. And coronary heart disease(CHD) is the most common type of heart disease, which kills over 300,000 people in 2015.

Heart disease is caused by a process of plaques building up on the arterial wall, leading to hardening and narrowing of the arteries in resulting of harder for blood to flow through. If a blood clot forms, it can stop the blood flow. and cause heart diseases.

Today researchers do not why some people are susceptible to plaques forming on the arteries, while other with the same condition and similar diet pattern and life style do not.

Depending to the location where clots were formed, symptoms of heart disease can be classified as follows
* Symptoms caused by abnormal heartbeats (heart arrhythmias) include slow heartbeat (bradycardia) chest pain or discomfort,  shortness of breath, lightheadedness,... and dizziness.

* Symptoms caused by heart defects include light gray or blue skin color, swelling in the legs, abdomen,..... and swelling areas around the eyes.

* Symptoms caused by weak heart muscle include swelling of the legs, ankles and feet, irregular heartbeats,... and dizziness and fainting.

* Symptoms caused by heart infections include shortness of breath,  fatigue,.... and  swelling in your legs or abdomen.

* Symptoms caused by valvular heart disease include fatigue, shortness of breath, irregular heartbeat,.... and swelling on the feet or ankles.

Heart diseases which are diagnosed early are easy to treat, some researchers suggested that if you experience prolonged chain pain, shortness of breath and frequent fainting, you may have heart diseases, please make sure you check with your doctor to rule out the possibility.

Yoga, the ancient practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the review literature extracted from Medline/PubMed, Scopus, the Cochrane Library, and IndMED up to October 2013 in evaluated quality of evidence and the strength of recommendation for yoga as an ancillary intervention for heart disease. 7 Seven RCTs met the criteria selected with a total of 624 patients participated in yoga class showed
* Yoga therapy reduced a number of angina episodes.

* There were low evidences suggested that yoga reduced modifiable cardiac risk factors, heart failure, and improved health-related quality of life.

* Yoga intervention group also showed insignificantly effects on patients with nonfatal device-treated ventricular events

Dr. Cramer H, the led author said, "RCTs reported safety data and reported that no adverse events occurred" and " ..... weak recommendations can be made for the ancillary use of yoga for patients with coronary heart disease".

Truly, yoga slow breathing enhances arterial  muscle to relax and  posture improves blood flow in the arteries in provided nutrients and oxygen to the body needs, thus reducing the risk of narrowing arteries in induction of blood clots.

Furthermore, by normalizing the blood flow in the arteries, yoga also reduces risk of symptoms that cause diminishing quality of life in people with high risk of heart disease

Additionally,  in the analysis of some publication, researchers at the Sir Ganga Ram Hospital showed that
* Some randomized studies expressed favorably that yoga may be effect in both early and advanced coronary atherosclerosis.

* Yoga participants also showed to improved atrial fibrillation.


However, in a review of the updated publication by searching the broaden database from Cochrane Central Register of Controlled Trials (CENTRAL) in The Cochrane Library (Issue 1 of 12, 2014), MEDLINE (1948 to February week 1 2014), EMBASE (1980 to 2014 week 6), Web of Science (Thomson Reuters, 1970 to 12 February 2014), China Journal Net (1994 to May 2014), WanFang Data (1990 to May 2014), and Index to Chinese Periodicals of Hong Kong (HKInChiP) (from 1980) up to 2012. to examine the influence of yoga practice on CHD outcomes in men and women (aged 18 years and over) with a diagnosis of acute or chronic CHD, researchers indicated that there were no studies met the guideline and criteria, therefore, recommended use of yoga for secondary prevention in CHD remains uncertain.

n that concerns of the yoga efficacy, Dr. Manchanda SC, the led author said, "most studies have several limitations like lack of adequate controls, small sample size, inconsistencies in baseline and different methodologies,.." and "therefore large trials with improved methodologies are required to confirm these findings".


Taking altogether, yoga may have some evidences in reduced risk and treatment of heart disease, but a cohost and large sample size of study are necessary before yoga intervention is recommended as secondary therapy.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) A systematic review of yoga for heart disease by Cramer H1, Lauche R2, Haller H2, Dobos G2, Michalsen A3.(PubMed)
(2) Yoga for secondary prevention of coronary heart disease by Lau HL1, Kwong JS, Yeung F, Chau PH, Woo J.(PubMed)
(3) Effects of yoga on cardiovascular disease risk factors: a systematic review and meta-analysis by Cramer H1, Lauche R2, Haller H2, Steckhan N3, Michalsen A4, Dobos G2.(PubMed)

Asparagus, The Functional Food Which Normalize Levels of Blood Cholesterol and Prevents Lipid Peroxidation

By Kyle J. Norton, Master of Nutrition

Asparagus may have a potential and therapeutic effect in normalize levels of blood cholesterol in patients who were diagnosed hyperlipidemia, some scientists suggested.

Cholesterol is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat.

However too much of it can be dangerous because cholesterol cannot dissolve in your blood.

Hyperlipidemia is a medical condition characterized by abnormally elevated levels lipids (fats) in the blood, including cholesterol and triglyceride.

In other words, hyperlipidemia can also defined as a raised LDL-c, triglyceride-rich lipoprotein excess, and increased lipoprotein(a) as well as lowered HDL-c, according to the secondary causes of hyperlipidemia by Dr. Stone NJ.

The exact causes of abnormally elevated levels lipids (fats) are debatable. Some researchers suggested that certain medical conditions such as diabetes mellitus, kidney disease, and hypothyroidism may also have a positive influence on the onset of the syndrome.

According to the Guangxi Medical University, in the comparisoeroln of the effect of hyperglycemia among the Han who are the largest group and Bai Ku Yao who are the isolated subgroup of the Yao minority, researchers after considering other con and co founders at the end of the experiment said, "The prevalence of hyperlipidemia was significantly lower among ethnic Bai Ku Yao than among ethic Han individuals, which might mainly be attributed to the more favorable dietary patterns, lifestyle choices, and physical activity levels in the former ethnic group".

These results strongly insisted that unhealthy diet and life style play important roles in initiation of the onset of hyperlipidemia.

Most patients with hyperlipidemia do not experience any symptoms. Hyperlipidemia is usually detected during a routine blood test, or following a cardiovascular event, such as a heart attack or stroke..

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia.

The plant or food has been used from early times as a vegetable and medicine, because of its delicate flavor and diuretic properties.

In the study of the effects of asparagus (500 mg/kg body weight (bw)/day) and their partially purified fractions in flavonoids (50 mg/kg bw/day), saponins (5 mg/kg bw/day) and dietary fiber (500 mg/kg bw/day) on oxidative status and on lipid profile in rats fed a cholesterol-rich diet, researchers found after 5 weeks, administration of asparagus improves the plasma lipid profile and prevents hepatic oxidative damage under conditions of hypercholesterolemia through its bioactive constituents, especially dietary fiber and flavonoids.

Furthermore, treated groups also exhibited a significant increase in enzyme activity from multiple hepatic antioxidants produced by the host, including: superoxide dismutase, catalase, and gluthhatione reductase/peroxidase as well as a decrease in MDA concentrations in compared to HCD group.

These results showed that asparagus ant its bioactive compounds also process anti oxidative and lipidperoxidative activities.

Moreover, additonal analysis also found that intake of asparagus does not have any effect on levels of HDL cholesterol.

Dr. García MD, the lead author at the final report, wrote, " the intake of green asparagus from Andalusia (Spain) helps to regulate plasma lipid levels and prevents oxidative damage in hypercholesterolemic conditions".

However, further data collection on large example size and multi centers clinical studies performed with human consumption of the whole food during the course of the condition will be necessary to complete the picture of asparagus hypolipidemic possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Reference
(1) Bioactive constituents from "triguero" asparagus improve the plasma lipid profile and liver antioxidant status in hypercholesterolemic rats. by Vázquez-Castilla S, De la Puerta R, Garcia-Gimenez MD, Fernández-Arche MA, Guillén-Bejarano R.(PubMed)
(2) Hypocholesterolemic and hepatoprotective effects of "triguero" asparagus from andalusia in rats fed a high cholesterol diet by García MD, De la Puerta R, Sáenz MT, Marquez-Martín A, Fernández-Arche MA. (PubMed)
(4) Associations of diet and lifestyle with hyperlipidemia for middle-aged and elderly persons among the Guangxi Bai Ku Yao and Han populations by Ruixing Y1, Jinzhen W, Yaoheng H, Jing T, Hai W, Muyan L, Yiyang L, Dongmei F, Hanjun Y, Yuming C(PubMed)

Herbal Butterbur, The Anti Acute and Chronic Migraine Herbal and Functional Remedy, Scientists Say

Herbal butterbur may be considered as functional herb in protection of neurons against change in the brain and its surrounding blood vessels in initiated onset of migraine, some scientists suggested.

Migraine headache is one most common headache defined as condition of chronic neurological disorder of moderate to severe headaches, and nausea that usually develop gradually over 5–20 minutes and last for less than 60 minutes.

According to the statistic, the syndrome affects over 15% of the population in US.  If you are women your risk of migraine headache is at 2 times higher in compared to men.

Sadly, 1 in 7 people in the world population will develop migraine headache at some points in their life time, And, chronic migraine affects about 2% of the world population.

Some patients during migraine attack also suffer symptoms of visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch and smell, and tingling or numbness in the extremities or face.

Believe or not, 10% school age children also suffer from undiagnosed migraine headache.

Conventional medicine in reduced symptoms of pain during attack such as Sumatriptan, Rizatriptan,..and Eletriptan may be effective but they may induce certain side effects, including gastrointestinal discomfort, dizziness, drowsiness,... and muscle weakness.

Please make sure that you discuss these side effect with your doctor before taking.

Butterbur, found in wet, marshy, damp land, including wetland, riverside, forest, etc., is a creeping underground plant, genus Petasites of 15 -20 species, belonging to the family Asteraceae, native to Northern Hemisphere.

The herb has been used in herbal medicne used as an pain reliever in digestive system, including stomach, bile ducts, and duodenum, etc.

The Chemical constituents
The chemical constituents of Butterbur include Petioles, petasitene and pethybrene, quercetin 3-O-beta-D-glucoside, quercetin 3-O-beta-D-6''-O-acetylglucoside, and rutin, caffeic acid, alkaloids, S-petasin and iso-S-petasin, etc.

Although the herb is used as nutritional supplement in US, scientific studies suggested that it may be used as the prevention of allergic rhinitis and treatment of migraine.

In a three-arm, parallel-group, randomized trial comparing Petasites extract 75 mg bid, Petasites extract 50 mg bid, or placebo bid in 245 patients with migraine, satisfied the International Headache Society criteria, researchers found that by calculating the migraine attack frequency per month as percentage change from baseline over a 4-month treatment period

* Migraine attack frequency was reduced by 48% for Petasites extract 75 mg bid (p = 0.0012 vs placebo), 36% for Petasites extract 50 mg bid (p = 0.127 vs placebo), in compared to 26% of placebo group.

* The proportion of patients with a > or =50% reduction in attack frequency after 4 months was 68% for patients in the Petasites extract 75-mg arm and 49% for the placebo arm (p < 0.05).
* In compared to the baseline, patients, intake of Petasites 75 mg also also expressed a significant effect in reduced migraine at 1, 2, and 3 months.

* Mild adverse effects such as gastrointestinal events, predominantly burping. were also reported.

These results sugegsted that butterbur Petasites extract 75 mg bid is more effective than placebo and is well tolerated as a preventive therapy for migraine.

Furthermore, in the review to confirm the strength of evidence of effectiveness for Petasites hybridus in treating prophylaxis of migraine by searching several databases and other sources to identify randomised-controlled trials, the Headache Center Hirslanden in Zürich, Switzerland found 2 trials totalling 293 patients (60 and 233 patients).

According to the selected trials, oral administrated butterbur extract at higher dose (150 mg) expressed a greater decreased frequency of migraine attacks and a greater number of responders (improvement>50%) after treatment over 3-4 months in compared to the extract at lower dose (100 mg) and placebo.

Additional differentiation also found some evidences that higher than the recommended dose may be more effective in treating prophylaxis of migraine.  

More profoundly, in the study of 60 patients received either the special Petasites hybridus extract Petadolex or placebo at a dosage of two capsules (each capsule contains 25 mg) twice daily over 12 weeks, researchers found that 

* Oral injection of the capsules Petadolex reduces the frequency of migraine attacks decreased by a maximum of 60 percent in compared to the baseline.

* No adverse events were reported. Petasites was exceptionally well tolerated.


Taking altogether,  herbal butterbur extract may be considered as  therapeutic treatment in  acute and chronic migraine headache, however, exact dose should only be prescribed by herbalist.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
References
(1) Petasites hybridus root (butterbur) is an effective preventive treatment for migraine by Lipton RB, Göbel H, Einhäupl KM, Wilks K, Mauskop A.(PubMed)
(2) An extract of Petasites hybridus is effective in the prophylaxis of migraine by Grossman W, Schmidramsl H.(PubMed)
(3) Effectiveness of Petasites hybridus preparations in the prophylaxis of migraine: a systematic review by Agosti R, Duke RK, Chrubasik JE, Chrubasik S.(PubMed)

Wednesday, 19 September 2018

Yoga Intervention Improves Overall Conditions of Patients With Coronary Heart Disease

Kyle J. Norton (Master of Nutrients, All right reserved)

Yoga may have a profound and positive impact on secondary prevention and improvement on overall conditions in individuals with coronary heart disease, some studies suggested.

Coronary artery disease is a medical condition caused by accumulation of plaques that block arteries in supply blood nutrients and oxygen to the heart. Most cases of the disease is associated to atherosclerosis, the condition of hardening of the arteries.

According to statistic, coronary artery disease is the most common type of heart disease that cause death of over  370,000 people every years, representing 28% of all death in the United States.

Sadly, according to the Centers For Disease Control and Prevention, approximately, 735,000 Americans have a heart attack each year.

What cause plaques building up on the arterial are debatable. However, researchers suggested that Western diet is associated to significantly increased risk of coronary artery disease.

Dr. Venegas-Pino DE in the classification of the effect of diet on heart diseases said," the western-diet-fed male ApoE-/-:Ins2+/Akita mouse, with profound cardiovascular disease involving extensive atherosclerosis, coronary artery disease and myocardial infarct resulting in shortened lifespan(4)".

Most common symptoms of coronary artery disease is angina, the condition characterized by chest pain or discomfort and shortness of breath as a result of weakening of heart muscle which can not pump enough blood to the body needs.

Over time, prolonged weakened heart muscle can lead to complications of heart failure, irregular heartbeat, or arrhythmia.

Yoga, the ancient practice for harmonized external and internal body well being, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia.

In a total of 80 stable CAD patients below 65 years of age of both sexes selected and randomized into two groups of 40 each. yoga Group I with for 3 months yoga lessons consisted yogic postures, pranayama breathing exercises, dietary modification, and holistic teaching along with their conventional medicine while Group II treated only on conventional medicine after 3 months, researchers found that,

*Groups attended yoga lessons expresses statistically significant improvements slow vital capacity, forced vital capacity, peak expiratory flow rate, maximum voluntary ventilation, and diffusion factor/ transfer factor of lung for carbon monoxide in compared to group II.

* The lung function in forced respiratory volume in 1(st) sec (FEV1), and FEV1 % also shows a trend toward improvement although not statistically significant in also compared to conventional treatment group.

Dr, Yadav A, the led authors after the experiment said, "Yoga regimen was found to improve lung functions and diffusion capacity in CAD patients besides improving cardiovascular functions".

These results suggested that yoga postures and meditation have a profound effect in relaxed arterial muscle to allow more blood to flow through by reduced stress which causes the muscle wall  tightening.

Furthermore, yoga posture and breathing technique also improved the lung muscle in absorption of more oxygen for the blood.

In support of the above analysis, Dr. Pal A, and colleagues conducted a study of 258 patients from the Department of Cardiology in Chhatrapati Shahuji Maharaj Medical University diagnosed with coronary artery disease randomly divided into 2 groups, the yoga group and the non-yoga group with 129 in each group, yoga attendees after 35-40 min/day, 5 days a week over a period of 18 months displayed a statistically significant reduction in body mass index, waist circumference, systolic and diastolic blood pressure, and heart rate (P < 0.05).

The relaxation to allow more blood to provide nutrients and oxygen to the body needs may also result in reduced the blood pressure, thus lowering the heart rate.

After taking into account of other risk factors, researchers suggested that yoga therapy expressed a significant effect on secondary prevention of mortality and morbidity and health-related quality of life of individuals with coronary heart disease,


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of yoga regimen on lung functions including diffusion capacity in coronary artery diseasepatients: A randomized controlled study by Yadav A1, Singh S2, Singh K2, Pai P1.(PubMed)
(2) Effect of yogic intervention on the autonomic nervous system in the patients with coronary artery disease: a randomized controlled trial by Pal A, Srivastava N, Narain VS, Agrawal GG, Rani M.(PubMed)
(3) Yoga for secondary prevention of coronary heart disease by Lau HL1, Kwong JS, Yeung F, Chau PH, Woo J.(PubMed)
(4) Evidence of extensive atherosclerosis, coronary artery disease and myocardial infarction in the ApoE-/-:Ins2+/Akita mouse fed a western diet by Venegas-Pino DE1, Lagrotteria A2, Wang PW3, Morphet J3, Clapdorp C3, Shi Y3, Werstuck GH(PubMed)

Carrot, The Functional Food Which Reduces Gastric/Stomach Cancer Risk By 26%

Kyle J. Norton

Carrots may have a profound and positive effect in reduced risk, progression and treatment of gastric cancer, some scientists suggested.

Gastric cancer is a slowly developed condition characterized by cell growth uncontrollably and disorderly in the stomach tissue. At he later stage, the cancerous cells may travel a distance away to infect other healthy cells of the tissue and organs.

According to the US cancer society, approximately over 26000 new cases of gastric cancer are diagnosed in 2018 inducing death of over 10,000 patients.

The risk that a man and woman will develop gastric cancer in their lifetime is 1 in 95 and 1 in 154 respectively.

The exact causes of gastric cancer are unknown, some researchers suggested that older people, male, heavy smokers, people who with family history of gastric cancer and certain ethnic groups such as
Asian (especially Korean or Japanese), South American, or Belarusian descent are at increased prevalent risk of gastric cancer.

Interestingly, during past several decades, the numbers of common gastric cancer are showed a tendency of receding, however, at the same time, cancer at the area where the top part of the stomach  meets the lower end of the swallowing tube (esophagus) has increased rapidly.

Also, some medical conditions such as lymphoma, H. pylori bacterial infections,  tumors in  digestive system and stomach polyps are  associated to risk of the disease.

If you experiment of persistent feeling floated after eating, and small meal after eating, heart burn, indigestion,... and stomach pain accompanied of general symptoms of cancer such as unexplained weight loss, please check with your doctor to rule out the possibility of gastric cancer..

Carrot, a root vegetable with orange color is a sub spices of Daucus carota, belongings to the family Apiaceae, native to Asian and Europe.

In the investigation the hypothesis of "eating carrots may play a major role in the prevention of gastric cancer", researchers at the joint study lead by the J Shahid Sadoughi University of Medical Sciences conducted a medical literature review selected from the data bases of including PubMed, Cochrane Library, Scopus, ScienceDirect, and Persian databases like Scientific Information Database (SID) and IranMedx, those studies satisfied the guidelines and criteria showed that risk of gastric cancer reduced by 26% with the consumption of carrots.

After taking into account of other co factors, researchers warranted that the result does not showed the possibility of a publication bias, according to the funnel graph by comprehensive meta analysis/2.0 software.

Although without mentioning the amount intake daily, these results showed an inverse relationship between the consumption of carrots and the risk of gastric cancer.

Furthermore, in the analysis of the effect of Helicobacter pylori (H. pylori) overgrowth in risk of gastric cancer, scientists found that injection of gene of UreB into carrot by Agrobacterium-mediated transformation expressed a significant effect in regenerated carrot plants the expressed UreB protein accounted for 25mug/g roots in reduced expression of H. pylori.

The same application also showed a similar effect in immune response in inhibition of infection of bacterial Helicobacter pylori in mice.

These result suggested that certain chemical compounds in carrot may consist a strong anti micro organism activity by protecting the plant against bacterial infection.

Therefore, UreB transgenic carrot can be potentially used as an edible vaccine for controlling H. pylori but also ameliorated risk of the bacteria in induction of gastric cancer.



The illustration of above differentiation were supported by the study conducted by the Graduate School of Fudan University.

According to the evaluation of the Wuxing soup containing Daikon Radish Leaves (Green element) Daikon Radish (White element) Carrots (Red color element) Burdock Root (Yellow element) Shittake Mushroom (Black element), application of the soup to the human gastric adenocarcinoma cell line (SGC-7901) expressed a huge inhibitory activity in reduced tumor cells proliferation in a time and dose dependent manner.

More importantly, Wuxing soup induced tumor cell death through apoptotic morphological changes and DNA ladder of the tested SGC-7901 cells.

Additionally, used combination with calcium inhibitor Bapta AM, an intracellular calcium chelator not only exerted a strong effect in  reduced the cancer apoptotic rate but also protected SGC-7901 cells in a dose dependent manner.

Dr. Mo F, the lead author said, "Wuxing soup has an effective inhibition on cancer cells, and can induce SGC-7901 cells to apoptosis by calcium".

Taken together, carrot may be considered as a function food in ameliorated risk and used combination with conventional standard treatment for gastric cancer.

However, further data collection on large example size and multi centers studies performed with human consumption of the whole food during the course of gastric cancer will be necessary to complete the picture of carrot's anti cancer possibilities.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca
Biography

Kyle J. Norton(Scholar, Master of Nutrition), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Effect of Carrot Intake in the Prevention of Gastric Cancer: A Meta-Analysis by Fallahzadeh H1, Jalali A2, Momayyezi M1, Bazm S3.(PubMed)
(2) Oral immunogenicity and protective efficacy in mice of a carrot-derived vaccine candidate expressing UreB subunit against Helicobacter pylori by Zhang H1, Liu M, Li Y, Zhao Y, He H, Yang G, Zheng C.(PubMed)
(3) [The anti-tumour effect of Wuxing soup and its mechanism in inducing apoptosis of tumour cells mediated by calcium].[Article in Chinese] by Mo F1, Hu JY, Gan Y, Zhao YX, Zhao XT.(PubMed)

Green Tea,The Popular Beverage Which Blocks The Entry Point of Bacterium That Cause Tuberculosis

Kyle J Norton

Green tea may have a therapeutic and positive effect in reduced risk and progression and treatment of tuberculosis (TB), some scientists suggested.

Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis. Commonly, the bacteriium attacked the lung tissue but in some cases they also can cause major damage to other parts of the body.

The disease is very contagious, as types of bacteria that cause TB can spread from person to person through microscopic droplets released into the air.

In other words, people can be infected by TB if they can to closely contact with TB patients through tuberculosis coughs, speaks, sneezes, spits,.... and laughs.

Bacterium called Mycobacterium tuberculosis are the main culprits that cause TB. The disease is rare in the Western world, however, according to the report of WHO of the region including 36 countries in the Western Pacific Region, approximately 1.4 million notified cases of all forms of TB in 2011 (75 per 100 000 population), corresponding to 23% of the total cases notified globally.

There were 0.6 million new smear-positive cases notified in 2011 (32 per 100 000 population), corresponding to 22% of the total smear-positive cases notified globally.

Conventional medicine Isoniazid (INH) is quite effective and considered as the primary therapy for latent TB. Most patients are required to take an isoniazid antibiotic pill daily for 9 months.

It you are taking Isoniazid (INH) and experience nausea, vomiting, rash, fever, ataxia, slurring of speech, peripheral neuritis, dizziness and stupor within 30 minutes to two hours after ingestion, you should go to hospital right the way as in some cases, the symptoms may follow with complications of grand mal seizures and coma.

Please make sure you understand the risk which may be induced by the medicine.

Green tea, is a precious drink processed numbers of health benefit and known to almost everyone in Asia and Western world.

In the investigation of the effect of reactive oxygen species (ROS) in risk of tuberculosis of a total of 200 newly diagnosed cases of AFB positive pulmonary tuberculosis, with 100 patients randomly received catechin (500 microg) with antitubercular treatment (ATT) (cases) and the other 100 received starch (500 microg) with ATT (control), researchers at the Chhatrapati Shahuji Maharaj Medical University found that CTN treatment group exerts a significant activity in reduced levels of free radical expression through reduced oxidative stress in compared to control, observed by analysis of the blood samples.

Further analysis suggested that green tea CTN treatment group restores the balances antioxidant and free radicals ratio by stimulated production of levels of enzymatic antioxidant (catalase, superoxide dismutase, glutathione peroxidase) and non enzymatic antioxidant (total thiol, reduced glutathione) levels and significant decreased expression of free radicals (lipid peroxidation, nitric oxide).

These results re-constituted the efficacy of crude catechin extract as adjuvant therapy in management of oxidative stress seen in pulmonary tuberculosis patients.

Moreover, in monitor the extent of oxidative stress in mice infected with M tuberculosis and the role of crude green tea extract in repairing the oxidative damage by divided them into three groups of normal, infected-untreated and infected-treated with 9 members in each group, scientists indicated that infectous untreated group exerted a significant enhancement of antioxidants produced by the natural defense of the body such as erythrocytic catalase and glutathione peroxidase activities along with elevated levels of free radical defenders such as erythrocytic total thiols but decreased levels of antioxidant activity of superoxide dismutase and glutathione in erythrocytes and increased levels of free radicals plasma lipid peroxidation as compared to normal animals as expected.


These results suggested that non CTN tested mice exerted the protection against application of infectious agent selectively either through expression of natural antioxidant produced by the body or antioxidants produced by the body were inhibited by the injection substance.

Importantly, ingestion of green tea CTN upon 7 days in infectious mice group completely restored the normal values of antioxidants and ROS ratio observed by the oxidative stress parameters.

In other words, green tea treatment group showed an increased catalase, glutathione peroxidase, total thiol and decreased extent of lipid peroxidation with concomitant increase in the levels of SOD and glutathione in infected animals, thus reducing development of tuberculosis risk.


The above differentiation were supported by the Department of Experimental Medicine and Biotechnology, Chandigarh in the study to determine whether or not polyphenols derived from green tea could down-regulate tryptophan-aspartate containing coat protein (TACO) gene transcription in reduced uptake/survival of M. tuberculosis within macrophages.

TACO gene transcription allows mycobacterial entry/survival within a mobile white blood cell, especially at sites of infection.of the innate immune system,

According to the reverse-transcriptase polymerase chain reaction and reporter assay technology, application of major component of green tea polyphenols, epigallocatechin-3-gallate EGCG reduced expression of TACO gene transcription within white blood cells in the immune system through its ability in inhibited Sp1 transcription factor in initiation of infectious cellular processes.

Sp1 transcription factor plays an important role in cell differentiation, cell growth, apoptosis, immune responses.
Dr. Anand PK, the lead authors, said, "The down-regulation of TACO gene expression by epigallocatechin-3-gallate was accompanied by inhibition of mycobacterium survival within macrophages as assessed through flow cytometry and colony counts" and "epigallocatechin-3-gallate may be of importance in the prevention of tuberculosis infection".

Taken together, green tea and its bioactive polyphenols in attenuated risk and treatment of tuberculosis caused by Mycobacterium tuberculosis may contribute significantly to the prevention and treatment of tuberculosis in third world countries where the conventional medicine are scarce or un-affordable to general population.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


Sources
(1) Effect of green tea extract (catechins) in reducing oxidative stress seen in patients of pulmonary tuberculosis on DOTS Cat I regimen by Agarwal A1, Prasad R, Jain A.(PubMed)
(2) Protective effect of green tea extract against the erythrocytic oxidative stress injury during mycobacterium tuberculosis infection in mice by Guleria RS1, Jain A, Tiwari V, Misra MK.(PubMed)
(3) Green tea polyphenol inhibits Mycobacterium tuberculosis survival within human macrophages by Anand PK1, Kaul D, Sharma M.(PubMed)

Tuesday, 18 September 2018

Herbal Anise Detoxes Your Kidney From Medicine and Chemicals Toxicity, Scientists Say

Kyle J. Norton 

Anise may have a potential and therapeutic effect in reduced risk of nephrotoxicity caused by intake of some medicine and chemicals, some scientists suggested.

Nephrotoxicity or acute kidney failure is a condition of toxicity in the kidneys.

The disease is caused by a poisonous effect of prolonged use of certain medication and accumulation of harmful chemicals.

According to the American physician association, long term use of penicillins, cephalosporins, sulfonamides, thiazide diuretics, furosemide, NSAIDs and rifampicin are associated to increase damage to the kidney.

And people with age over 60 are at increased risk of nephrotoxicity, if the above medicne are prescribed for prolonged periods.

Continuously, the association wrote, "Drug-induced nephrotoxicity tends to be more common among certain patients and in specific clinical situations" and " Drugs cause approximately 20 percent of community-and hospital-acquired episodes of acute renal failure".

Dr. Koren G, in the classification of drug and chemicals that cause nephrotoxicity suggested, "Drugs and chemicals may affect renal function by pharmacologically decreasing glomerular filtration rate and/or renal blood flow" and " A variety of xenobiotics or their metabolites may be deposited in the renal tubule causing obstruction of urine flow and a secondary damage to tubular epithelium"(4).

If you experience symptoms of decreased urine output,.fluid retention that causes legs, ankles or feet. swelling,.... and shortness of breath, you may have acute kidney failure, please check with you doctor to rule out the possibility.

Anise is a flowering plant ofthe species of Pimpinella anisum, genus Pimpinella, belonging to the family Apiaceae native to to Egypt and the Mediterranean region,  used in traditional herbal medicine as fragrance in soaps, oils, and mouth fresheners and stomachic, anti-septic, anti-spasmodic, ....


Chemical comstituents
Anethole, D-pinene, I-phellandrene, Alpha-terpineol, Safrol, Methyl chavicol, Resin, Shikimic acid, etc.

In the investigation of the effect of Pimpinella anisum (P. anisum) in alleviated gentamicin (GM) in induction of nephrotoxicity, in a group of 40 male wistar rats divided into four groups: control, sham administrated normal saline orally and intraperitoneally (i.p.), GM received 100 mg/kg bw/day and GM and ethanolic extract of P. anisum with an oral dose of 300 mg/kg bw/day for 8 days, researchers found that GM groups demonstrates a significant increase of plasma levels of creatinine which in an indication of improper function of kidneys,  levels of Blood urea nitrogen (BUN) which is an indication of how the kidneys in filtered out the wastes and levels of malondialdehyde (MDA), a maker of oxidative stress.

Mice injected with GM also displayed an absolutely increased excretion of sodium and potassium inducing fluid or electrolyte imbalances and impaired kidney function.

Oral GM adminstrated mice also showed a  decreased level of reducing ability of plasma (FRAP) level, a marker of antioxidant defense in compared to the sham group. 

Interestingly, application of herbal anise in GM group at dose of 300 mg/kg expressed an improvement of various aspects through significantly reduced the plasma concentrations of renal function markers and gentamicin-induced tubule damage.

Dr. Changizi-Ashtiyani S, the lead author said, " the potential therapeutic impact of P. anisum to attenuate GM-induced nephrotoxicity. Therefore, the simultaneous use of ethanolic extract of P. anisum during GM administration is recommended to reduce its nephrotoxicity effects".

Amazingly, in the study to evaluate the effect  Pimpinella anisum L. against lead intoxication in induction of nephrotoxicity in young rats intoxicated by lead acetate, researchers found that  oral adminstration of aqueous extract of P. anisum L. (500 and 750 mg/kg) for 15 days show an strong improvement in reduced expression of urea, creatinine, acid uric, and gamma-GT by  −71%, −1.23%, −1.80% and −5.88% of kidney damage bioamrkers caused by lead toxicity.

Importantly, injection of anise extracted also decreased the level of lipid hydroperoxide (LPO) of −13.56%, an indication of antioxidant activity induced by the application
 and increased the concentration of total proteins (+8.88%) in expression of kidney and liver protective effects without changing histological structures of the kidney between the studied groups.

Dr. Bekara Amina, the lead author, after taking into account of other con founders, said, "P. anisum L. may have a nephroprotective potential against harmful effect induced by lead toxicity on kidney".

Moreover, in the study of a total of 40 male Wister albino rats divided randomly into four groups (1st group was control; 2nd group treated with star anise, 3 rd group received Etoposide, and 4th group treated with both star anise and Etoposide(chemotherapy medication used for the treatments of a number of types of cancer), application of the herbal products, displayed similar efficacy as those in ansie through significantly decreased elevation in creatinine, blood urea, sodium, potassium and chloride while calcium ions induced in the injection of Etoposide.

The study also addressed the inter uncorrelated between star anise water extract and the injection of Etoposide observed by assay supported the detrimental effect of Etoposide in the ameliorating effect of star anise water extract on renal toxicity.

Dr. Ali Salman Hassan according to the information findings said, "star anise has a promising role and it worth to be considered as a natural substance for ameliorating the renal toxicity and injury induced by Etoposide chemotherapy".

Taken together, Anise may be considered as an adjunct therapy in combined with standard medicine in reduced risk of nephrotoxicity, particularly in patient undergoing chemotherapy for cancer treatment.

Intake of herbal extract should be taken with extreme care  in prevented liver toxicity.

However, further data collection on large example size and multi centers studies performed with human consumption of the whole food during the acute phase of the disease will be necessary to complete the picture of herbal anise kidney protective possibilities.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca


Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Pimpinella anisum L. ethanolic extract ameliorates the gentamicin- induced nephrotoxicity in rats by Changizi-Ashtiyani S1, Seddigh A2, Najafi H3, Hossaini N4, Avan A5, Akbary A6, Manian M7, Nedaeinia R8.(PubMed))
(2) Prevention of Etoposide induced kidney toxicity, electrolytes, injury and KI67 alternations in male rats tre ated with star anise Ali Salman Hassan Al-Ameri Environmental studies/Biology/Ministry of Education, Iraq(JBAAR)
(3) Nephroprotective effect of Pimpinella anisum L. aqueous extract against lead toxicity: In vivo study by Bekara Amina, Ait Hamadouche, Kahloulakhaled, Aoues Abdelkader(Research Gate)
(4) The nephrotoxic potential of drugs and chemicals. Pharmacological basis and clinical relevance by Koren G(PubMed)