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Monday, 20 January 2014

Phytochemical Allicin and anti cognitive activity

Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic. 
Cognition is the process of the brain including the attention of working memory, producing and comprehending language, learning, reasoning, problem solving, and decision making.

The benefits
Cognitive abilities tend to decline in aging. The study of allicin on endogenous antioxidant defenses in hippocampus of cognitively impaired aged mouse, showed a positive effects as allicin significantly ameliorated ageing-induced cognitive dysfunction through enhancing of Nrf2 antioxidant signaling pathways. Allcin also exerted its antioxidant effect in reducing the risk of cardiovascular disease, stroke, cancer and aging, including the oxidant-mediated brain cell damage that is implicated in Alzheimer's disease.



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References
(1)  Cognition (Wikipedia)
(2) Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways by Li XH, Li CY, Lu JM, Tian RB, Wei J.(PubMed)
(3) Antioxidant health effects of aged garlic extract by Borek C.(PubMed)