Tuesday, 21 January 2014

Serum potassium and leptospirosis

Dietary Minerals are the group of minerals essential for our body to sustain normal functions and physical health.
In General, potassium is a very essential mineral to the human body for maintaining to build proteins and muscle, break down carbohydrates, maintain normal body growth and normal heart electricity, etc.
The Normal serum potassium is 3.5 to 5.5 mEq/L. The total body potassium is lower in females and in older patients, serum potassium concentration is independent of sex and age.
Leptospirosis is disease caused by bacteria as a result of  contact with water, soil or food contaminated by urine from infected animals.

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Patient infected by bacteria cause of Leptospirosisis susceptible to hypokalemic acute renal failure characterized with low level of serum of potassium and sodium may be associated to increased risk of mortality. In the study to measure the levels of serum potassium and serum creatinine andduration of symptoms at admission, showed the death rate increased with serum potassium: 11.1% in the hypoK, 14.7% in the normoK and 47.1% in the hyperK group (p = 0.002). the result suggested that hypoK is an positive and independent risk correlated with the risk of in-hospital death and hyperK are directly associated to increase risk of mortality in patient with Leptospirosis. Other in the study of the same also indicated that older age was also strongly and independently associated with higher risk of death.

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(1) The association between serum potassium at hospital admission and the case-fatality rate of leptospirosis in men by Lopes AA, Costa E, Costa YA, Bina JC, Sacramento E.(PubMed)
(2) Comparative study of the in-hospital case-fatality rate of leptospirosis between pediatric and adult patients of different age groups by Lopes AA, Costa E, Costa YA, Sacramento E, de Oliveira Junior AR, Lopes MB, Lopes GB.(PubMed)

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