Kyle J. Norton
Hypertension is a condition of abnormally high blood pressure. It also is a member of the cluster of metabolic syndrome associated with the risk of diabetes and cardiovascular disease.
Blood pressure is the force of the blood pushing against the arterial walls. In high blood pressure, the heart has to work harder than normal to pump blood through the circulation system. Over time, high blood pressure has been found to cause damage to the heart and arteries.
High blood pressure can be acute or chronic. Acute high blood pressure most often occurs to people with sudden stress.
Sometimes, it can be caused by intense physical exercise. As the heart must pump harder to provide the needs of nutrients and oxygen.
People with high blood pressure in most cases are asymptomatic.
Most cases of chronic high blood pressure are associated with an unhealthy lifestyle and chronic diseases such as kidney disease, leading to the onset of strokes and cardiovascular disease.
On another hand, If you can control your diet, such as making changes to your lifestyle, maintaining ideal weight, and diet with low salt, you could do just fine without the drugs.
Epidemiologically, here are some natural remedies that will help you to lower high blood pressure, keeping it in the normal range of 130/80.
* Calcium and Magnesium
A combination of these 2 minerals with the right DOSAGES has a long and indisputable track record for normalizing blood pressure safely. Be sure to only take these compounds with a ratio of 2 to 1. Otherwise, this compound might cause an irregular heartbeat.
* Mediterranean diet
A study found that people in Greece and Italy always have ideal blood pressure, because their diet contains more polyunsaturated fat, such as olive oil. If you can replace saturated fat in your diet with extra virgin oil, you could easily normalize your blood pressure.
* Reducing Salt intake
Salt is a mineral composed of sodium and chloride. You need only half a tablespoon a day, but we consume many times more than that every day causing high blood pressure and increasing the risk of early death.
Avoid processed meat, because it has been soaked in salt. Use little Ketchup, mustard, and soy sauce because they contain high amounts of salt.
* Cigarette
If you smoke, you better quit. The nicotine in cigarettes and other tobacco products causes your blood vessels to constrict and your heart to beat faster, which temporarily raises your blood pressure.
* Alcohol
Alcohol might cause a temporary rise in blood pressure in some people. If you have high blood pressure, you should reduce your daily intake of alcohol to 1-2 cups.
* Relaxation
Stress may affect blood pressure. Managing stress, by relaxation techniques, such as yoga, lightweight exercise, aerobic exercise, can be healful.
Lycopene is a phytochemical in the class of carotenoids, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,
Tomatoes provide about 80% of the lycopene in the world's diet. In plants, lycopene protects the host against excessive photodamage and performs various functions in photosynthesis.
In finding a natural compound for the treatment of hypertension, researchers examined the tomato carotenoids such as lycopene anti-high blood pressure activity.
The double-blind, randomized, placebo-controlled study included patients with untreated hypertension individuals who received either 5, 15, and 30 mg of lycopene or 15 mg of synthetic lycopene or a placebo over eight weeks.
According to the tested analysis,* The effective doses of Tomato Nutrient Complex (TNC) that maintain normal blood pressure in untreated hypertensive individuals were 15 or 30 mg of lycopene associated with significant reductions in mean systolic blood pressure (SBP) compared to other treatments.
* Furthermore, Treatment with the lower dose standardized for 5 mg of lycopene or treatment with 15 mg of synthetic lycopene showed no significant effect on blood pressure.
* The increase in blood levels of lycopene was dose-dependent.
The results strongly suggested that only the TNC dose of 15 mg lycopene or higher has a beneficial effect on SBP in hypertension.
Taken together, lycopene found in tomatoes may be considered a supplement for the prevention and treatment of hypertension, pending the confirmation of the larger sample size and multicenter human study.
Intake of lycopene in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effect of Tomato Nutrient Complex on Blood Pressure: A Double Blind, Randomized Dose⁻Response Study by Wolak T1, Sharoni Y2, Levy J3, Linnewiel-Hermoni K4, Stepensky D5, Paran E. (PubMed)
(2) Lycopene and Vascular Health by Mozos I1,2, Stoian D3, Caraba A4, Malainer C5, Horbańczuk JO6, Atanasov AG. (PubMed)
Tuesday 21 November 2023
#Phytochemical Allyl isothiocyanate #AITC Induces Brain and Bladder Cancer Cell Apoptosis, According to Studies
Kyle J. Norton
Phytochemical Allyl isothiocyanate may be the next pharmacotherapeutic target to identify the chemo drug for the treatment of brain cancer without inducing any side effects.
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color.
The brain and spinal cord make up the nervous system. Brain and Spinal Cord tumors originating are not very common.
Brain cancer is a medical and chronic condition characterized by cell growth disorderly in the brain tissue.
Benign tumors are noncancerous, and malignant tumors are cancerous. More than 190.000 people in the US are diagnosed with a brain tumor each year alone.
Most brain types of brain cancer in older adults ages 50 to 60 are Chordomas. The cancer is a rare and slow-growing, but it can invade adjacent bone and put pressure on the nearby neural tissue.
Meningiomas, are the most common type of benign brain tumor of the age group 40-50s. However, a small percentage of these tumors can be malignant.
According to the statistic provided by the Canadian Cancer Society, Every day about 25 Canadians is diagnosed with a brain tumor.
The 5-year survival rate of brain cancer is only 25%, compared to over 60% for cancers overall. Most adults with a diagnosis of aggressive glioblastoma survive only 1–2 years after their diagnosis.
The exact causes of brain cancer are debatable. Researchers do not know why people with the same health conditions, and family history, are at a higher risk to develop brain cancer while others do not.
Some researchers suggested genetic preposition and acquired gene mutation due to long-term exposure to chemical toxins may be the prevalent risk factor that causes the alternation of brain cell DNA.
The most common symptoms of brain cancer depending on the stage are persistent headaches and localized pain, gradual loss of sensation and movement, speech difficulty, and persistent pain
If you are experiencing some of the above symptoms, please make sure you check with your doctor immediately to rule the brain cancer possibility.
Allyl isothiocyanate is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in horseradish, mustard, wasabi, etc.
Most primary tumors are caused by abnormal cell growth that surrounds and supports neurons, with a small number that may be caused by a gene defect from exposure to radiation or toxic chemicals.
Examining the side effects of Allyl isothiocyanate from the available data suggests that urinary concentrations of AITC equivalent are at least ten times higher than in the plasma, and tissue levels of AITC equivalent in the urinary bladder were 14-79 times higher than in other organs after oral AITC administration to rats for the treatment of cancer.
These results indicated AITC may be most effective in the bladder as a cancer chemopreventive compound, as AITC at high-dose levels exhibited a low degree of cytotoxicity and genotoxicity in animal cancer studies.
Once again, the experiment reaffirmed the effect of AITC in the exhibition of many desirable attributes of a cancer chemopreventive agent.
In the reassessment of Allyl isothiocyanate (AITC) in the reduced risk of cancer, researchers at the National Chung Hsing University conducted an experiment to examine the effects of the phytochemical in brain cancer cells.
Compared to other cancer cell lines inhibition, AITC significantly decreased proliferation and viability of human brain malignant glioma GBM 8401 cells in a dose-dependent manner with IC50 9.25+/-0.69 microM for 24 h-treatment.
In cell differentiated assay, AITC induced significantly G2/M arrest and sub-G1 phase (apoptotic population) in GBM 8401 cells.
AITC markedly reduced the CDK1/cyclin B activity and protein levels which are responsible for cancer cell proliferation and survival.
Furthermore, AITC-induced apoptotic cell death through enhancing the proteins associated with cells death programming.
Dr. Chen NG, the lead scientist at the final report, said, "AITC is a potent anti-human brain malignant glioma drug and it shows a remarkable action on cell cycle arrest before a commitment for apoptosis is reached".
Taken together, it is safe to suggest that Phytochemical Allyl isothiocyanate may be used as a chemopreventive and functional phytochemical for high-risk brain cancer individuals and an adjunct therapy combined with primary medicine for the treatment of brain cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To ProfessionalPrediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway by Chen NG, Chen KT, Lu CC, Lan YH, Lai CH, Chung YT, Yang JS, Lin YC. (PubMed)
(2) Allyl isothiocyanate as a cancer chemopreventive phytochemical by Zhang Y.(PubMed)
Phytochemical Allyl isothiocyanate may be the next pharmacotherapeutic target to identify the chemo drug for the treatment of brain cancer without inducing any side effects.
Phytochemicals, the natural chemical constituent, protect the plants against diseases and form their outer's color.
The brain and spinal cord make up the nervous system. Brain and Spinal Cord tumors originating are not very common.
Brain cancer is a medical and chronic condition characterized by cell growth disorderly in the brain tissue.
Benign tumors are noncancerous, and malignant tumors are cancerous. More than 190.000 people in the US are diagnosed with a brain tumor each year alone.
Most brain types of brain cancer in older adults ages 50 to 60 are Chordomas. The cancer is a rare and slow-growing, but it can invade adjacent bone and put pressure on the nearby neural tissue.
Meningiomas, are the most common type of benign brain tumor of the age group 40-50s. However, a small percentage of these tumors can be malignant.
According to the statistic provided by the Canadian Cancer Society, Every day about 25 Canadians is diagnosed with a brain tumor.
The 5-year survival rate of brain cancer is only 25%, compared to over 60% for cancers overall. Most adults with a diagnosis of aggressive glioblastoma survive only 1–2 years after their diagnosis.
The exact causes of brain cancer are debatable. Researchers do not know why people with the same health conditions, and family history, are at a higher risk to develop brain cancer while others do not.
Some researchers suggested genetic preposition and acquired gene mutation due to long-term exposure to chemical toxins may be the prevalent risk factor that causes the alternation of brain cell DNA.
The most common symptoms of brain cancer depending on the stage are persistent headaches and localized pain, gradual loss of sensation and movement, speech difficulty, and persistent pain
If you are experiencing some of the above symptoms, please make sure you check with your doctor immediately to rule the brain cancer possibility.
Allyl isothiocyanate is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in horseradish, mustard, wasabi, etc.
Most primary tumors are caused by abnormal cell growth that surrounds and supports neurons, with a small number that may be caused by a gene defect from exposure to radiation or toxic chemicals.
Examining the side effects of Allyl isothiocyanate from the available data suggests that urinary concentrations of AITC equivalent are at least ten times higher than in the plasma, and tissue levels of AITC equivalent in the urinary bladder were 14-79 times higher than in other organs after oral AITC administration to rats for the treatment of cancer.
These results indicated AITC may be most effective in the bladder as a cancer chemopreventive compound, as AITC at high-dose levels exhibited a low degree of cytotoxicity and genotoxicity in animal cancer studies.
Once again, the experiment reaffirmed the effect of AITC in the exhibition of many desirable attributes of a cancer chemopreventive agent.
In the reassessment of Allyl isothiocyanate (AITC) in the reduced risk of cancer, researchers at the National Chung Hsing University conducted an experiment to examine the effects of the phytochemical in brain cancer cells.
Compared to other cancer cell lines inhibition, AITC significantly decreased proliferation and viability of human brain malignant glioma GBM 8401 cells in a dose-dependent manner with IC50 9.25+/-0.69 microM for 24 h-treatment.
In cell differentiated assay, AITC induced significantly G2/M arrest and sub-G1 phase (apoptotic population) in GBM 8401 cells.
AITC markedly reduced the CDK1/cyclin B activity and protein levels which are responsible for cancer cell proliferation and survival.
Furthermore, AITC-induced apoptotic cell death through enhancing the proteins associated with cells death programming.
Dr. Chen NG, the lead scientist at the final report, said, "AITC is a potent anti-human brain malignant glioma drug and it shows a remarkable action on cell cycle arrest before a commitment for apoptosis is reached".
Taken together, it is safe to suggest that Phytochemical Allyl isothiocyanate may be used as a chemopreventive and functional phytochemical for high-risk brain cancer individuals and an adjunct therapy combined with primary medicine for the treatment of brain cancer.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To ProfessionalPrediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Allyl isothiocyanate triggers G2/M phase arrest and apoptosis in human brain malignant glioma GBM 8401 cells through a mitochondria-dependent pathway by Chen NG, Chen KT, Lu CC, Lan YH, Lai CH, Chung YT, Yang JS, Lin YC. (PubMed)
(2) Allyl isothiocyanate as a cancer chemopreventive phytochemical by Zhang Y.(PubMed)
#CruciferousVegetables and Celecoxib Modulates Oncogenic Activity Against the Onset of #BladderCancer, Researchers Say
Kyle J. Norton
Allyl isothiocyanate is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in horseradish, mustard, wasabi, etc.
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excretes it through the urethra.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women. Usually, it starts from the bladder lining caused by several types of malignant growths of the urinary bladder cells.
The study of AITC found cruciferous vegetables and celecoxib effects in modulating cyclooxygenase-2 (Cox-2), as its oncogenic activity has been well documented in bladder cancer and other cancers, this effectiveness is a result of associated with depletion of prostaglandin E2, a key downstream signaling molecule of Cox-2, caspase activation and downregulation of vascular endothelial growth factor in the tumor tissues.
In another study, the N-acetylcysteine conjugate (NAC-AITC) is found to be a significant inhibition of cell growth and proliferation in human bladder cancer UM-UC-3 cells or rat bladder cancer AY-27 cells with NAC-AITC at 15 μM.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
1. Enhanced inhibition of urinary bladder cancer growth and muscle invasion by allyl isothiocyanate and celecoxib in combination by Bhattacharya A, Li Y, Shi Y, Zhang Y(PubMed)
(2) The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer by Bhattacharya A, Li Y, Geng F, Munday R, Zhang Y.(PubMed)
Allyl isothiocyanate is a phytochemical containing sulfur in the class of organosulfur compounds, found abundantly in horseradish, mustard, wasabi, etc.
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excretes it through the urethra.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women. Usually, it starts from the bladder lining caused by several types of malignant growths of the urinary bladder cells.
The study of AITC found cruciferous vegetables and celecoxib effects in modulating cyclooxygenase-2 (Cox-2), as its oncogenic activity has been well documented in bladder cancer and other cancers, this effectiveness is a result of associated with depletion of prostaglandin E2, a key downstream signaling molecule of Cox-2, caspase activation and downregulation of vascular endothelial growth factor in the tumor tissues.
In another study, the N-acetylcysteine conjugate (NAC-AITC) is found to be a significant inhibition of cell growth and proliferation in human bladder cancer UM-UC-3 cells or rat bladder cancer AY-27 cells with NAC-AITC at 15 μM.
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
References
1. Enhanced inhibition of urinary bladder cancer growth and muscle invasion by allyl isothiocyanate and celecoxib in combination by Bhattacharya A, Li Y, Shi Y, Zhang Y(PubMed)
(2) The principal urinary metabolite of allyl isothiocyanate, N-acetyl-S-(N-allylthiocarbamoyl)cysteine, inhibits the growth and muscle invasion of bladder cancer by Bhattacharya A, Li Y, Geng F, Munday R, Zhang Y.(PubMed)
Friday 17 November 2023
#GreenPeas (Pisum Sativum) Supplementation Ameliorates the Risk and Severity of #Colitis, Researchers Say
Kyle J. Norton
Colitis is a general term associated with the inflammation of the inner lining of the colon.
The disease can be caused by infection, inflammatory bowel disease (Crohn's disease (CD), ulcerative colitis(CD)), ischemic colitis, allergic reactions, and microscopic colitis.
Most cases of colitis are involved in the damage of the intestinal mucosal barrier, particularly to those of ulcerative colitis.
Epidemiologically, damage and a reduction of gut bacteria by dietary chemicals, such as antibiotics of the protective mucus layer and the underlying tissue by the poorly inactivated digestive proteases have been found to induce both UC and CD.
The intestinal mucosal barrier is the outermost inner layer of the lining of the intestines which plays an essential role in ensuring the adequate containment of undesirable luminal contents within the intestine while preserving the ability to absorb nutrients.
Additionally, the intestinal mucosal barrier also processes various immunological mediators, including cytokines and chemokines stimulated by gut microbiota and host immune responses, thus maintaining a well-balanced relationship between gut microbes and the host immune system.
In other words, the intestinal mucosal barrier protects the colonic integrity by interacting with the gut microbiota and the immune response to prevent the inflammation of the colon that causes the onset of colitis.
Some researchers suggested the promotion of a high-fat diet over the past few decades may be one of the most prevalent factors that increase the risk of colitis.
Dr. Max Gulhane, the lead scientist wrote, "Prolonged high-fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and diets high in saturated fat are a risk factor for the development of human inflammatory bowel diseases".
And, "HFD-induced endoplasmic reticulum (ER)/oxidative stress occur in intestinal secretory goblet cells, triggering inflammatory signaling and reducing synthesis/secretion of proteins that form the protective mucus barrier".
The finding strongly suggested the mucosal barrier dysfunction induced by a high-fat diet involved in colitis.
Green peas are a species of Pisum Sativum belonging to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalayan Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
In finding a potent ingredient that processes anti-inflammatory activity with oxidative stress, researchers investigated the impact of green pea (GP) supplementation on the susceptibility of a high-fat diet (HFD) in an animal model.
The study included Six-week-old C57BL/6J female mice randomly assigned into groups fed a 45% HFD or HFD supplemented with 10% GP. After 7-week dietary supplementation, colitis induced by adding 2.5% DSS in drinking water for 7 days followed by a 7-day recovery period.
According to the tested analysis, GP supplementation ameliorated the disease activity index score in HFD-fed mice by reducing the expression of pro-inflammatory cytokines.
Furthermore, inflammatory markers associated with inflammatory proteins and enzymes such as interleukin (IL)-6, cyclooxygenase-2 (COX-2), IL-17, interferon-γ (IFN-γ), and inducible nitric oxide synthase (iNOS) in HFD-fed mice were also decreased by GP supplement.
Goblet cell differentiation markers in HFD-fed mice. associated with mucus secretion and function during the stage of inflammation were also increased by the administration of GP supplementation.
Furthermore, endoplasmic reticulum (er) stress-induced production of pro-inflammatory cytokines in HFD-fed mice was also inhibited by GP supplement.
Based on the findings, researchers wrote, "GP supplementation ameliorated the severity of DSS-induced colitis in HFD-fed mice, which was associated with the suppression of inflammation, mucin depletion, and ER stress in the colon".
Taken together, green peas may be considered a functional food for the prevention and treatment of colitis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Green Pea Protects against DSS-Induced Colitis in Mice Challenged with High-Fat Diet by Bibi S1, de Sousa Moraes LF2, Lebow N3, Zhu MJ. (PubMed)
(2) High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22 by Max Gulhane,1 Lydia Murray,1 Rohan Lourie,1 Hui Tong,1 Yong H. Sheng,1 Ran Wang,1 Alicia Kang,2Veronika Schreiber,1 Kuan Yau Wong,1 Graham Magor,3 Stuart Denman,4 Jakob Begun,1 Timothy H. Florin,1Andrew Perkins,3 Páraic Ó. Cuív,2 Michael A. McGuckin,1 and Sumaira Z. Hasnaina. (PMC)
Colitis is a general term associated with the inflammation of the inner lining of the colon.
The disease can be caused by infection, inflammatory bowel disease (Crohn's disease (CD), ulcerative colitis(CD)), ischemic colitis, allergic reactions, and microscopic colitis.
Most cases of colitis are involved in the damage of the intestinal mucosal barrier, particularly to those of ulcerative colitis.
Epidemiologically, damage and a reduction of gut bacteria by dietary chemicals, such as antibiotics of the protective mucus layer and the underlying tissue by the poorly inactivated digestive proteases have been found to induce both UC and CD.
The intestinal mucosal barrier is the outermost inner layer of the lining of the intestines which plays an essential role in ensuring the adequate containment of undesirable luminal contents within the intestine while preserving the ability to absorb nutrients.
Additionally, the intestinal mucosal barrier also processes various immunological mediators, including cytokines and chemokines stimulated by gut microbiota and host immune responses, thus maintaining a well-balanced relationship between gut microbes and the host immune system.
In other words, the intestinal mucosal barrier protects the colonic integrity by interacting with the gut microbiota and the immune response to prevent the inflammation of the colon that causes the onset of colitis.
Some researchers suggested the promotion of a high-fat diet over the past few decades may be one of the most prevalent factors that increase the risk of colitis.
Dr. Max Gulhane, the lead scientist wrote, "Prolonged high-fat diets (HFD) induce low-grade chronic intestinal inflammation in mice, and diets high in saturated fat are a risk factor for the development of human inflammatory bowel diseases".
And, "HFD-induced endoplasmic reticulum (ER)/oxidative stress occur in intestinal secretory goblet cells, triggering inflammatory signaling and reducing synthesis/secretion of proteins that form the protective mucus barrier".
The finding strongly suggested the mucosal barrier dysfunction induced by a high-fat diet involved in colitis.
Green peas are a species of Pisum Sativum belonging to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalayan Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.
In finding a potent ingredient that processes anti-inflammatory activity with oxidative stress, researchers investigated the impact of green pea (GP) supplementation on the susceptibility of a high-fat diet (HFD) in an animal model.
The study included Six-week-old C57BL/6J female mice randomly assigned into groups fed a 45% HFD or HFD supplemented with 10% GP. After 7-week dietary supplementation, colitis induced by adding 2.5% DSS in drinking water for 7 days followed by a 7-day recovery period.
According to the tested analysis, GP supplementation ameliorated the disease activity index score in HFD-fed mice by reducing the expression of pro-inflammatory cytokines.
Furthermore, inflammatory markers associated with inflammatory proteins and enzymes such as interleukin (IL)-6, cyclooxygenase-2 (COX-2), IL-17, interferon-γ (IFN-γ), and inducible nitric oxide synthase (iNOS) in HFD-fed mice were also decreased by GP supplement.
Goblet cell differentiation markers in HFD-fed mice. associated with mucus secretion and function during the stage of inflammation were also increased by the administration of GP supplementation.
Furthermore, endoplasmic reticulum (er) stress-induced production of pro-inflammatory cytokines in HFD-fed mice was also inhibited by GP supplement.
Based on the findings, researchers wrote, "GP supplementation ameliorated the severity of DSS-induced colitis in HFD-fed mice, which was associated with the suppression of inflammation, mucin depletion, and ER stress in the colon".
Taken together, green peas may be considered a functional food for the prevention and treatment of colitis, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Dietary Green Pea Protects against DSS-Induced Colitis in Mice Challenged with High-Fat Diet by Bibi S1, de Sousa Moraes LF2, Lebow N3, Zhu MJ. (PubMed)
(2) High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22 by Max Gulhane,1 Lydia Murray,1 Rohan Lourie,1 Hui Tong,1 Yong H. Sheng,1 Ran Wang,1 Alicia Kang,2Veronika Schreiber,1 Kuan Yau Wong,1 Graham Magor,3 Stuart Denman,4 Jakob Begun,1 Timothy H. Florin,1Andrew Perkins,3 Páraic Ó. Cuív,2 Michael A. McGuckin,1 and Sumaira Z. Hasnaina. (PMC)
Regular Intake of #Onion Is Associated with a Reduced Risk of #Cancer, According to Studies
Kyle J. Norton
Cancer is a group of medical conditions caused by irregular cell growth in the tissues and organs due to the alternation of cell DNA.
Most cases of cancer start in the cells on the surface of the inner lining of the infected tissue or argan before penetrating into the deeper layers to form a tumor.
Certain factors have been found to affect prognosis including
* The type of cancer and where it is in your body
*The stage of cancer, most often refers to the size and metastasis of cancer.
** Stage 0
Cancer is classified as Stage 0 if the cancerous cell has not penetrated deeper tissue but on the surface of the inner lining.
** Stage I
In stage I, The cancerous cells are no longer in the surface but have invaded the deep lung lining, but still completely inside the lung.
***Stage IA1
The cancer is ≤ 3 mm (1/8 inch) deep and ≤ 7 mm (1/4 inch) wide.
**** Stage IA1: The spreading is < 3mm(1/8 inch) deep and & less than 7mm (1/4 inch) wide.
**** Stage IA2: The invasion area is ≥ 3 mm but ≤ 5 mm (about 1/5 inch) deep and & less than 7 mm (about 1/4 inch) wide.
***. Stage IB: cancer in this stage has invaded the connective tissue, & less than 5mm (1/5 inch).
**** Stage IB1: Cancer is 4 cm large (1 3/4 inches).
**** Stage IB2: Cancer is ≥ 4 cm (1 3/4 inches) but & less than 5cm (1/5 inch)
**Stage II
In stage II, the cancerous cells have spread to distant tissues but are still within the organ.
**Stage III
At this stage, cancerous cells have spread to the tissues immediately surrounding the organ.
**Stage IV
The stage, IV is the most advanced stage of cancer as cancerous cells have spread to distant parts of the body
In this stage, cancerous cells have spread to the tissues immediately surrounding the organ.
* Cancer’s grade, low-grade cancers usually grow more slowly and are less likely to spread while high-grade cancer indicates otherwise.
* Certain traits of cancer cells include
** How cancer cell stimulates their own growth
** How cancer cells resist inhibitory signals that stop their growth
** How cancer cells inhibit programmed cell death signaling.
Some researchers also include the age, health of patients, and how patients responded to previous cancer treatment
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
To find a potential compound for the treatment of cancer, researchers examined the effect of garlic and onion on certain types of cancer.
Intake of onion is found inversely associated with the risk of onions or garlic and cancers of the oral cavity/pharynx, larynx, renal cells, breast, ovary, and endometrium.
More precisely, people who eat onions ≥7 times/week have the OR of oral cavity/pharyngeal cancers of 0.16, laryngeal cancer of 0.17, and ovarian cancer of 0.27 compared to those who did not eat onions.
Furthermore, according to the study of cases from the Hawaii Tumor Registry and controls randomly selected from a list of Oahu residents, intake of onion was associated with decreased risk of lung cancer with the OR = 0.5 in the highest quartile of intake compared to the lowest.
In prostate cancer, the Italian study suggested that both onions and garlic did not have significantly decreased OR of prostate cancer compared to those with the lowest intake, However, increasing intake showed a trend of decreasing the ORs.
In esophageal cancer, the intake of raw garlic/onion at least once per week has the adjusted OR of esophageal cancer of 0.2.
In colorectal cancer, the Italian and Swiss case-control studies found that both onions show a protective effect against colon cancer regardless of the amount of intake onion intake compared to non-consumers of onion.
In stomach cancer, according to the meta-analysis, consumption of large amounts of total Allium vegetables, such as garlic and onion reduced the risk of gastric cancer by comparing the highest and lowest consumption groups.
Taken together, onion may be considered a remedy for cancer prevention, pending confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Garlic and onions: Their cancer prevention properties by Holly L. Nicastro,1 Sharon A. Ross,2 and John A. Milner. (PubMed)
(2) Understanding Cancer Prognosis (NIH)
Cancer is a group of medical conditions caused by irregular cell growth in the tissues and organs due to the alternation of cell DNA.
Most cases of cancer start in the cells on the surface of the inner lining of the infected tissue or argan before penetrating into the deeper layers to form a tumor.
Certain factors have been found to affect prognosis including
* The type of cancer and where it is in your body
*The stage of cancer, most often refers to the size and metastasis of cancer.
** Stage 0
Cancer is classified as Stage 0 if the cancerous cell has not penetrated deeper tissue but on the surface of the inner lining.
** Stage I
In stage I, The cancerous cells are no longer in the surface but have invaded the deep lung lining, but still completely inside the lung.
***Stage IA1
The cancer is ≤ 3 mm (1/8 inch) deep and ≤ 7 mm (1/4 inch) wide.
**** Stage IA1: The spreading is < 3mm(1/8 inch) deep and & less than 7mm (1/4 inch) wide.
**** Stage IA2: The invasion area is ≥ 3 mm but ≤ 5 mm (about 1/5 inch) deep and & less than 7 mm (about 1/4 inch) wide.
***. Stage IB: cancer in this stage has invaded the connective tissue, & less than 5mm (1/5 inch).
**** Stage IB1: Cancer is 4 cm large (1 3/4 inches).
**** Stage IB2: Cancer is ≥ 4 cm (1 3/4 inches) but & less than 5cm (1/5 inch)
**Stage II
In stage II, the cancerous cells have spread to distant tissues but are still within the organ.
**Stage III
At this stage, cancerous cells have spread to the tissues immediately surrounding the organ.
**Stage IV
The stage, IV is the most advanced stage of cancer as cancerous cells have spread to distant parts of the body
In this stage, cancerous cells have spread to the tissues immediately surrounding the organ.
* Cancer’s grade, low-grade cancers usually grow more slowly and are less likely to spread while high-grade cancer indicates otherwise.
* Certain traits of cancer cells include
** How cancer cell stimulates their own growth
** How cancer cells resist inhibitory signals that stop their growth
** How cancer cells inhibit programmed cell death signaling.
Some researchers also include the age, health of patients, and how patients responded to previous cancer treatment
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
To find a potential compound for the treatment of cancer, researchers examined the effect of garlic and onion on certain types of cancer.
Intake of onion is found inversely associated with the risk of onions or garlic and cancers of the oral cavity/pharynx, larynx, renal cells, breast, ovary, and endometrium.
More precisely, people who eat onions ≥7 times/week have the OR of oral cavity/pharyngeal cancers of 0.16, laryngeal cancer of 0.17, and ovarian cancer of 0.27 compared to those who did not eat onions.
Furthermore, according to the study of cases from the Hawaii Tumor Registry and controls randomly selected from a list of Oahu residents, intake of onion was associated with decreased risk of lung cancer with the OR = 0.5 in the highest quartile of intake compared to the lowest.
In prostate cancer, the Italian study suggested that both onions and garlic did not have significantly decreased OR of prostate cancer compared to those with the lowest intake, However, increasing intake showed a trend of decreasing the ORs.
In esophageal cancer, the intake of raw garlic/onion at least once per week has the adjusted OR of esophageal cancer of 0.2.
In colorectal cancer, the Italian and Swiss case-control studies found that both onions show a protective effect against colon cancer regardless of the amount of intake onion intake compared to non-consumers of onion.
In stomach cancer, according to the meta-analysis, consumption of large amounts of total Allium vegetables, such as garlic and onion reduced the risk of gastric cancer by comparing the highest and lowest consumption groups.
Taken together, onion may be considered a remedy for cancer prevention, pending confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Garlic and onions: Their cancer prevention properties by Holly L. Nicastro,1 Sharon A. Ross,2 and John A. Milner. (PubMed)
(2) Understanding Cancer Prognosis (NIH)
Wednesday 8 November 2023
#Phytochemical #Betacyanins Reduce Chemo-Drug Toxicity and Overcome Multidrug Resistance of Cancer Cells, Researchers Say
Kyle J. Norton
Cancer is a class of disease characterized by cell growth disorderly and uncontrollably in the tissues and organs.
The most common cancers are
* Breast cancer, accounted for 25.4% of the total number of new cases diagnosed in 2018.
Breast cancer starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there are also rare cases of breast cancer that start in other areas of the breast. The risk of getting invasive breast cancer during the lifetime of women is 1/8.
Luckily, the 5 years survival rate of localized breast cancer is about 100%.
* Colorectal cancer and lung cancers are the second and third most common cancers, accounting for 43.9% of all cancers, excluding non-melanoma skin cancer.
Colorectal cancer is cancer in the colon, rectum, or vermiform appendix. Colorectal cancer is a relatively very common and slowly growing and progressing cancer.
The 5-year survival rate of the localized stage of colorectal cancer is about 90%.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells.
Lung cancer can also be classified into
* Non-small cell lung cancer
Non-small cell lung cancer is the most common type of lung cancer. It usually grows and spreads methodically and predictably.
* Small cell lung cancer
Small cell lung cancer is a fast-growing type of lung cancer, it can spread to distant parts of the body in a relatively early stage.
The overall 5-year survival rate of lung cancer is about 60%.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
In the finding, of the health benefits of Betacyanins, researchers compared the effect of green beet (Beta vulgaris var. cicla L.) and red beetroot (B. vulgaris var. Rubra L.) phytochemicals that benefit human health.
According to the chemical analysis, green beet contains apigenin, vitexin, vitexin-2-O-xyloside, and vitexin-2-O-rhamnoside, compared to the red beetroot as a source of betaxanthins and betacyanins.
All phytochemicals found in green and red beet show considerable antioxidant, anti-inflammatory, and antiproliferative activities.
From a cancer perspective, vitexin-2-O-xyloside combined with betaxanthins and betacyanins, exerts a significant antiproliferative activity in breast, liver, colon, and bladder cancer cell lines, through the induction of cancer cell apoptosis.
Additionally, betacyanins and other phytochemicals found in the green and red beet inhibited the pro-survival and anti-apoptotic genes, and modulated proteins associated with angiogenesis.
Moreover, betaxanthins and betacyanins used in combination with conventional anticancer drugs were found to reduce chemo-drug toxicity and overcome the multidrug resistance of cancer cells.
Based on the findings, researchers concluded betacyanins may be used alone or combined with other phytochemicals or chemo drugs to block the onset of the proliferation of tumor cells.
Taken together, betacyanins may be considered a remedy for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES. (PubMed)
Cancer is a class of disease characterized by cell growth disorderly and uncontrollably in the tissues and organs.
The most common cancers are
* Breast cancer, accounted for 25.4% of the total number of new cases diagnosed in 2018.
Breast cancer starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there are also rare cases of breast cancer that start in other areas of the breast. The risk of getting invasive breast cancer during the lifetime of women is 1/8.
Luckily, the 5 years survival rate of localized breast cancer is about 100%.
* Colorectal cancer and lung cancers are the second and third most common cancers, accounting for 43.9% of all cancers, excluding non-melanoma skin cancer.
Colorectal cancer is cancer in the colon, rectum, or vermiform appendix. Colorectal cancer is a relatively very common and slowly growing and progressing cancer.
The 5-year survival rate of the localized stage of colorectal cancer is about 90%.
Lung cancer is a condition of the abnormal growth of the cells in the lung's tissue. The most common form of primary lung cancer is derived from epithelial cells.
Lung cancer can also be classified into
* Non-small cell lung cancer
Non-small cell lung cancer is the most common type of lung cancer. It usually grows and spreads methodically and predictably.
* Small cell lung cancer
Small cell lung cancer is a fast-growing type of lung cancer, it can spread to distant parts of the body in a relatively early stage.
The overall 5-year survival rate of lung cancer is about 60%.
Betacyanins are phytochemicals in the class of red and yellow indole-derived pigments, belonging to the group of Betalains, found abundantly in beets, chard, etc.
In the finding, of the health benefits of Betacyanins, researchers compared the effect of green beet (Beta vulgaris var. cicla L.) and red beetroot (B. vulgaris var. Rubra L.) phytochemicals that benefit human health.
According to the chemical analysis, green beet contains apigenin, vitexin, vitexin-2-O-xyloside, and vitexin-2-O-rhamnoside, compared to the red beetroot as a source of betaxanthins and betacyanins.
All phytochemicals found in green and red beet show considerable antioxidant, anti-inflammatory, and antiproliferative activities.
From a cancer perspective, vitexin-2-O-xyloside combined with betaxanthins and betacyanins, exerts a significant antiproliferative activity in breast, liver, colon, and bladder cancer cell lines, through the induction of cancer cell apoptosis.
Additionally, betacyanins and other phytochemicals found in the green and red beet inhibited the pro-survival and anti-apoptotic genes, and modulated proteins associated with angiogenesis.
Moreover, betaxanthins and betacyanins used in combination with conventional anticancer drugs were found to reduce chemo-drug toxicity and overcome the multidrug resistance of cancer cells.
Based on the findings, researchers concluded betacyanins may be used alone or combined with other phytochemicals or chemo drugs to block the onset of the proliferation of tumor cells.
Taken together, betacyanins may be considered a remedy for the prevention and treatment of cancer, pending the confirmation of the larger sample size and multicenter human study.
Intake of betacyanins in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES. (PubMed)
#Healthyfood #Papaya Controls Glucose and Reduces the Risk of Complications in Diabetics, Researchers Say
Kyle J. Norton
Papaya may be the next generation of whole foods for the prevention and treatment of type II diabetes with no side effects, some studies suggested.
Diabetes is a condition characterized by insufficient insulin entering the bloodstream to regulate glucose.
Most cases of type II diabetes are either caused by cells in the pancreas that died off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Epidemiological studies suggested that obesity, family history, ethnicity, the increase in age, gestation diabetes, and polycystic ovary syndrome. and high blood pressure is the most common risk factor associated with the onset of prediabetes and type II diabetes.
Dr. Stephen S. Rich, in the article "the genetics of Diabetes and Its complications", suggested that type II diabetes may be a genetically related disease. Unlike type 1 diabetes, in which there seems to be an autoimmune process, type 2 diabetes is a disease of relative rather than absolute insulin deficiency. Genes involved in type 2 diabetes, with the most promising, replicated findings on chromosomes are 1q21-q24, 2q37, 12q24, and 20.
Untreated and unmanageable type II diabetes may induce complications of the onset of cardiovascular disease, and nerve damage (neuropathy). kidney damage (nephropathy), eye damage (retinopathy). foot damage and skin conditions.
Medication used for the treatment of type II diabetes is focused on alleviating the symptoms improving quality of life and slowing down the progression of the disease.
If you currently intake medicine for the treatment of diabetes, please sure you know all the side effects for the preventive measure.
Papaya is a species of Carica Papaya, belonging to the family Caricaceae and native to the tropics of the Americas, and was first cultivated in Mexico several centuries
Unripe pawpaw fruit (Carica papaya) not only inhibited α-amylase, and α-glucosidase but also reduced lipid peroxidation in a dose-dependent manner, in rat pancreas(1).
The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to the onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the postprandial increase of blood glucose and has been used for the management of blood glucose levels in type 2 diabetic and borderline patients by therapists (2).
In the streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(3), through the prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(4)
In a new study, conducted by researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(5).
The result was astonishing, the fermentation not only up-regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates several cellular functions)(5).
A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of the Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for 14 weeks could improve the general health status of several organs targeted by oxidative stress during diabetes and the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(6).
Taken together, unripe, fermented papaya and its' leaves may be effective in diabetic management by controlling the levels of glucose and reducing the risk of complications.
Some Western researchers insisted that large sample sizes and multicenter studies are necessary to validate its effectiveness by identifying the ingredients that are comparable to recent pharmaceutical medicine in use because geography, environment, time of harvest, etc. may influence the concentration of the food cultivation.
In fact, herbalists have long acknowledged that the external factors (mentioned above) may alter the quality of the herbs and foods by classifying these differences either through price or formula differentiation.
Indeed, the effectiveness with little or no adverse side effects of the formula is not the concentration of individual herbs and the herb itself but the interaction of all ingredients in an herb and herbs in the same formula. Extracting only one ingredient of the herb for the treatment of certain diseases may be effective but enhance complicated consequences.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO. (PubMed)
(2) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(3) Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(4) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(5) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(6) Effects of a short term supplementation of a fermented papayapreparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
(6) Genetics of Diabetes and Its Complications by Stephen S. Rich
Papaya may be the next generation of whole foods for the prevention and treatment of type II diabetes with no side effects, some studies suggested.
Diabetes is a condition characterized by insufficient insulin entering the bloodstream to regulate glucose.
Most cases of type II diabetes are either caused by cells in the pancreas that died off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
Epidemiological studies suggested that obesity, family history, ethnicity, the increase in age, gestation diabetes, and polycystic ovary syndrome. and high blood pressure is the most common risk factor associated with the onset of prediabetes and type II diabetes.
Dr. Stephen S. Rich, in the article "the genetics of Diabetes and Its complications", suggested that type II diabetes may be a genetically related disease. Unlike type 1 diabetes, in which there seems to be an autoimmune process, type 2 diabetes is a disease of relative rather than absolute insulin deficiency. Genes involved in type 2 diabetes, with the most promising, replicated findings on chromosomes are 1q21-q24, 2q37, 12q24, and 20.
Untreated and unmanageable type II diabetes may induce complications of the onset of cardiovascular disease, and nerve damage (neuropathy). kidney damage (nephropathy), eye damage (retinopathy). foot damage and skin conditions.
Medication used for the treatment of type II diabetes is focused on alleviating the symptoms improving quality of life and slowing down the progression of the disease.
If you currently intake medicine for the treatment of diabetes, please sure you know all the side effects for the preventive measure.
Papaya is a species of Carica Papaya, belonging to the family Caricaceae and native to the tropics of the Americas, and was first cultivated in Mexico several centuries
Unripe pawpaw fruit (Carica papaya) not only inhibited α-amylase, and α-glucosidase but also reduced lipid peroxidation in a dose-dependent manner, in rat pancreas(1).
The key enzymes of α-amylase, α-glucosidase, involved in the digestion of carbohydrates, have been linked to the onset of type 2 diabetes. Inhibition of these enzymes can significantly reduce the postprandial increase of blood glucose and has been used for the management of blood glucose levels in type 2 diabetic and borderline patients by therapists (2).
In the streptozotocin-induced diabetic rats study, the aqueous extract of leaves of C. papaya administered strongly controlled blood glucose levels(3), through the prevention of hepatocyte disruption, as well as accumulation of glycogen and lipids via its hypoglycemic and antioxidant effect(4)
In a new study, conducted by researchers at the Davis Heart and Lung Research Institute, fermented papaya preparation was tested whether it improves dermal wound healing outcomes in adult diabetic mice by preventing the risk of infections(5).
The result was astonishing, the fermentation not only up-regulated the Sp1 DNA binding activity(modulating the cellular response to DNA damage) in Peripheral blood mononuclear cells (PBMC) but also the protein and mRNA expression of Rac2(regulates several cellular functions)(5).
A randomized controlled clinical trial conducted at the Cardiac Centre, ANDI Centre of Excellence for Biomedical and Biomaterials Research and Department of the Biosciences University of Mauritius, suggested that oral administration of 6g FPP®/day for 14 weeks could improve the general health status of several organs targeted by oxidative stress during diabetes and the supplement may be used in the management the complications of diabetes such as cardiovascular disease, neurological disease and other conditions worsened by overt inflammation and oxidative stress(6).
Taken together, unripe, fermented papaya and its' leaves may be effective in diabetic management by controlling the levels of glucose and reducing the risk of complications.
Some Western researchers insisted that large sample sizes and multicenter studies are necessary to validate its effectiveness by identifying the ingredients that are comparable to recent pharmaceutical medicine in use because geography, environment, time of harvest, etc. may influence the concentration of the food cultivation.
In fact, herbalists have long acknowledged that the external factors (mentioned above) may alter the quality of the herbs and foods by classifying these differences either through price or formula differentiation.
Indeed, the effectiveness with little or no adverse side effects of the formula is not the concentration of individual herbs and the herb itself but the interaction of all ingredients in an herb and herbs in the same formula. Extracting only one ingredient of the herb for the treatment of certain diseases may be effective but enhance complicated consequences.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.References
(1) Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water-extractable phytochemicals from unripe pawpaw fruit (Carica papaya) by Oboh G, Olabiyi AA, Akinyemi AJ, Ademiluyi AO. (PubMed)
(2) Natural products as alpha-amylase and alpha-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update by Tundis R1, Loizzo MR, Menichini F.(PubMed)
(3) Antihyperglycemic and hypolipidemic activities of aqueous extract of Carica papaya Linn. leaves in alloxan-induced diabetic rats by Maniyar Y, Bhixavatimath P.(PubMed)
(4) Hypoglycemic effect of Carica papaya leaves in streptozotocin-induced diabetic rats by Juárez-Rojop IE1, Díaz-Zagoya JC, Ble-Castillo JL, Miranda-Osorio PH, Castell-Rodríguez AE, Tovilla-Zárate CA, Rodríguez-Hernández A, Aguilar-Mariscal H, Ramón-Frías T, Bermúdez-Ocaña DY.(PubMed)
(5) Correction of aberrant NADPH oxidase activity in blood-derived mononuclear cells from type II diabetes mellitus patients by a naturally fermented papaya preparation by Dickerson R1, Deshpande B, Gnyawali U, Lynch D, Gordillo GM, Schuster D, Osei K, Roy S.(PubMed)
(6) Effects of a short term supplementation of a fermented papayapreparation on biomarkers of diabetes mellitus in a randomized Mauritian population by Somanah J1, Aruoma OI, Gunness TK, Kowelssur S, Dambala V, Murad F, Googoolye K, Daus D, Indelicato J, Bourdon E, Bahorun T.(PubMed)
(6) Genetics of Diabetes and Its Complications by Stephen S. Rich
#Cucumber Prevents Colonic Inflammation and Improves Digestive Functioning, Scientists Show
Kyle J. Norton
The gut microbiome made up of trillions of microorganisms is the bacterial composition found in the gut of the digestive tract.
In a healthy individual, the ratio of the bacterial composition is balanced. In other words, the bad bacteria in the digestive tract is totally countered by the presence of good bacteria.
However, the imbalanced ratio of the composition of the gut microbiota has been associated with chronic diseases ranging from inflammatory bowel disease (IBD), obesity, and allergic disorders, in both human and animal models.
Believe it or not, gut microbes have been found to influence many aspects of human health including immune, metabolic, and neurobehavioural traits.
In immunity, the balance of the gut microbes is shown to stimulate the immune function against inflammatory immune disorders.
Digestively, balanced gut microbes protect the gut against gastrointestinal diseases and non-gastrointestinal diseases. caused by overexpression of bad bacteria.
In metabolism, gut microbes influence what the human host is able to extract from its diet, such as nutrients, thus reducing the risk of obesity and obesity complications.
Neurologically, gut microbiota can control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.
Some researchers suggested, that there are huge benefits that influence the function of the brain, immunity, heart, and digestive system and reduce the risk of chronic diseases and conditions such as diabetes and metabolic syndrome by maintaining a good ratio of the gut microbiome.
The cucumber plant is a species of Cucumis Sativus, belonging to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows with the support of frames.
To discover a natural ingredient for balancing the ratio of microbiota composition, researchers investigated and evaluated cucumber phytochemical compositions along with their potential gut microbiota modulating, free radical scavenging, and anti-inflammatory capacities.
Seed flour extracts from cucumber enhanced the total number of gut bacteria by altering the abundance of specific bacterial phylum or genus in vitro.
In other words, cucumbers improved digestive functioning by enhancing the ratio of microbiota compositions in the gut.
Compared to broccoli and carrot seed flour extracts, cucumber seed extract showed the least effect in DPPH radical scavenging capacity, oxygen radical absorbing capacity, and hydrdoxyl radical (HO•) scavenging capacity values of 85, 634, and 270 μmol Trolox equivalent (TE)/g.
In the tested J774A.1 cells, cucumber suppressed the LPS-induced production of pro-inflammatory cytokines.
The results strongly suggested that the administration of Cucumis prevented colonic inflammation and improved digestive functioning by changing the gut microbiota composition.
To reveal more information about cumber in the improvement of gut microbiota, composition researchers examined Cucumis melo L. (Cucumis) on obesity-induced IR in genetically leptin-deficient Lepob/Lepob mice.
According to the tested assays, Cucumis improved IR and relieved inflammation in adipose tissue and blood which led to the balance of the ratio of microbiota composition.
Dr. Lee D, the lead scientist after taking into account co and confounders wrote, "administration of Cucumis improved IR by reducing inflammation, thereby changing the gut microbiota composition".
Taken together, fermented cucumber may be used for the treatment of digestive dysfunction by improving the ratio of gut microbiota composition, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Therapeutic Effect of Cucumis melo L. Extract on Insulin Resistance and the Gut Microbiome in Lepob/Lepob Mice by Lee D1, Yoo JH1, Lee BC. (PubMed)
(2) Chemical Compositions of Cold-Pressed Broccoli, Carrot, and Cucumber Seed Flours and Their in Vitro Gut Microbiota Modulatory, Anti-inflammatory, and Free Radical Scavenging Properties by Choe U1, Li Y1,2, Gao B2, Yu L1, Wang TTY, Sun J, Chen P, Liu J3, Yu L1. (PubMed)
The gut microbiome made up of trillions of microorganisms is the bacterial composition found in the gut of the digestive tract.
In a healthy individual, the ratio of the bacterial composition is balanced. In other words, the bad bacteria in the digestive tract is totally countered by the presence of good bacteria.
However, the imbalanced ratio of the composition of the gut microbiota has been associated with chronic diseases ranging from inflammatory bowel disease (IBD), obesity, and allergic disorders, in both human and animal models.
Believe it or not, gut microbes have been found to influence many aspects of human health including immune, metabolic, and neurobehavioural traits.
In immunity, the balance of the gut microbes is shown to stimulate the immune function against inflammatory immune disorders.
Digestively, balanced gut microbes protect the gut against gastrointestinal diseases and non-gastrointestinal diseases. caused by overexpression of bad bacteria.
In metabolism, gut microbes influence what the human host is able to extract from its diet, such as nutrients, thus reducing the risk of obesity and obesity complications.
Neurologically, gut microbiota can control brain insulin signaling and metabolite levels that play a critical role in neurobehaviors.
Some researchers suggested, that there are huge benefits that influence the function of the brain, immunity, heart, and digestive system and reduce the risk of chronic diseases and conditions such as diabetes and metabolic syndrome by maintaining a good ratio of the gut microbiome.
The cucumber plant is a species of Cucumis Sativus, belonging to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows with the support of frames.
To discover a natural ingredient for balancing the ratio of microbiota composition, researchers investigated and evaluated cucumber phytochemical compositions along with their potential gut microbiota modulating, free radical scavenging, and anti-inflammatory capacities.
Seed flour extracts from cucumber enhanced the total number of gut bacteria by altering the abundance of specific bacterial phylum or genus in vitro.
In other words, cucumbers improved digestive functioning by enhancing the ratio of microbiota compositions in the gut.
Compared to broccoli and carrot seed flour extracts, cucumber seed extract showed the least effect in DPPH radical scavenging capacity, oxygen radical absorbing capacity, and hydrdoxyl radical (HO•) scavenging capacity values of 85, 634, and 270 μmol Trolox equivalent (TE)/g.
In the tested J774A.1 cells, cucumber suppressed the LPS-induced production of pro-inflammatory cytokines.
The results strongly suggested that the administration of Cucumis prevented colonic inflammation and improved digestive functioning by changing the gut microbiota composition.
To reveal more information about cumber in the improvement of gut microbiota, composition researchers examined Cucumis melo L. (Cucumis) on obesity-induced IR in genetically leptin-deficient Lepob/Lepob mice.
According to the tested assays, Cucumis improved IR and relieved inflammation in adipose tissue and blood which led to the balance of the ratio of microbiota composition.
Dr. Lee D, the lead scientist after taking into account co and confounders wrote, "administration of Cucumis improved IR by reducing inflammation, thereby changing the gut microbiota composition".
Taken together, fermented cucumber may be used for the treatment of digestive dysfunction by improving the ratio of gut microbiota composition, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Therapeutic Effect of Cucumis melo L. Extract on Insulin Resistance and the Gut Microbiome in Lepob/Lepob Mice by Lee D1, Yoo JH1, Lee BC. (PubMed)
(2) Chemical Compositions of Cold-Pressed Broccoli, Carrot, and Cucumber Seed Flours and Their in Vitro Gut Microbiota Modulatory, Anti-inflammatory, and Free Radical Scavenging Properties by Choe U1, Li Y1,2, Gao B2, Yu L1, Wang TTY, Sun J, Chen P, Liu J3, Yu L1. (PubMed)
#Onion's #Quercetin inhibits Parameters Associated with the Risk of #Hypertension In the Induction of #Cardiovascular Disease, Researchers Say
Kyle J. Norton
Hypertension is a condition of abnormally high blood pressure in the bloodstream. Hypertension a member of the cluster conditions of metabolic syndrome associated with an increased risk of cardiovascular disease and diabetes.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.
Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistics, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million who were obese worldwide.
Bad eating habits, unhealthy lifestyles, and certain medical conditions such as kidney disease, diabetes, and sleep apnea not only induce overweight and obesity but also increase the risk of high blood pressure.
Dr. Shu-Zhong Jiang, the lead scientist wrote, "The imbalance between energy intake and expenditure is the main cause of excessive overweight and obesity. Technically, obesity is defined as the abnormal accumulation of ≥20% of body fat, over the individual's ideal body weight".
And, "Excessive overweight remains among the most neglected public health issues worldwide, while obesity is associated with increased risks of disability, illness, and death. Cardiovascular diseases, the leading cause of mortality worldwide, particularly hypertension and diabetes, are the main illnesses associated with obesity".
The results strongly suggested that obesity not only is associated with hypertension but also is a major contributor to the risk of other chronic diseases.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In finding a potential compound for the inhibition of hypertension, researchers examined the effects of polyphenol quercetin in pre-hypertension and stage I hypertension in overweight and obese individuals.
The double-blinded, placebo-controlled cross-over trial included 70 Subjects randomized to receive 162 mg/d quercetin from onion skin extract powder or placebo for 6 weeks separated by a 6-week washout period.
According to tested assays and compared to the baseline,
* The group treated with quercetin did not significantly show an effect on 24-hour ambulatory blood pressure (ABP) parameters and office BP in the hypertensives subgroup.
* However, quercetin decreased 24 h systolic BP by -3·6 mmHg (P=0·022) compared to placebo.
* Furthermore, quercetin treatment significantly decreased day-time and night-time systolic BP in hypertensives without alternating vasoactive biomarkers such as endothelial function, parameters of oxidation, inflammation, lipid, and glucose metabolism in the total and hypertensive subgroup.
Based on the findings, researchers said, " supplementation with 162 mg/d quercetin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quercetin".
In other words, supplementation with 162 mg/d quercetin from onion skin extract protects the heart against CVD by normalizing the blood pressure in hypertensive patients through unknown mechanisms.
Taken together, onion may be considered a remedy for the prevention and treatment of liver alcoholic cytotoxicity pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial by Brüll V1, Burak C1, Stoffel-Wagner B2, Wolffram S3, Nickenig G4, Müller C4, Langguth P5, Alteheld B1, Fimmers R6, Naaf S7, Zimmermann BF7, Stehle P1, Egert S. (PubMed)
(2) Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review by Lu M, Cao Y , Xiao J, Song M, and Ho CT. (PubMed)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)
Hypertension is a condition of abnormally high blood pressure in the bloodstream. Hypertension a member of the cluster conditions of metabolic syndrome associated with an increased risk of cardiovascular disease and diabetes.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
According to the statistics provided by the American Heart Association, approximately, 103 million U.S. adults have high blood pressure, or 1 in 2 adults in the US have the syndrome.
Obesity is a medical and chronic condition caused by long-term excessive body fat accumulated. Overweight is a condition of excess body weight relative to height.
According to the Body Mass Index(BMI), people who have a BMI between 25 to 29.9 are considered overweight and a BMI of over 30 is an indication of obesity.
The formula of the BMI indexBMI= weight (kg)/ height (m2)
According to the statistics, 68% of the American population is either overweight or obese. However,
in 2016, more than 1.9 billion adults, 18 years and older, were overweight, including over 650 million who were obese worldwide.
Bad eating habits, unhealthy lifestyles, and certain medical conditions such as kidney disease, diabetes, and sleep apnea not only induce overweight and obesity but also increase the risk of high blood pressure.
Dr. Shu-Zhong Jiang, the lead scientist wrote, "The imbalance between energy intake and expenditure is the main cause of excessive overweight and obesity. Technically, obesity is defined as the abnormal accumulation of ≥20% of body fat, over the individual's ideal body weight".
And, "Excessive overweight remains among the most neglected public health issues worldwide, while obesity is associated with increased risks of disability, illness, and death. Cardiovascular diseases, the leading cause of mortality worldwide, particularly hypertension and diabetes, are the main illnesses associated with obesity".
The results strongly suggested that obesity not only is associated with hypertension but also is a major contributor to the risk of other chronic diseases.
The onion is a plant in the genus Allium, belonging to the family Alliaceae, closely related to garlic. It is often called the "king of vegetables" because of its pungent taste and found in a large number of recipes and preparations spanning almost the totality of the world's cultures.
Depending on the variety, an onion can be sharp, spicy, tangy, pungent, mild or sweet.
In finding a potential compound for the inhibition of hypertension, researchers examined the effects of polyphenol quercetin in pre-hypertension and stage I hypertension in overweight and obese individuals.
The double-blinded, placebo-controlled cross-over trial included 70 Subjects randomized to receive 162 mg/d quercetin from onion skin extract powder or placebo for 6 weeks separated by a 6-week washout period.
According to tested assays and compared to the baseline,
* The group treated with quercetin did not significantly show an effect on 24-hour ambulatory blood pressure (ABP) parameters and office BP in the hypertensives subgroup.
* However, quercetin decreased 24 h systolic BP by -3·6 mmHg (P=0·022) compared to placebo.
* Furthermore, quercetin treatment significantly decreased day-time and night-time systolic BP in hypertensives without alternating vasoactive biomarkers such as endothelial function, parameters of oxidation, inflammation, lipid, and glucose metabolism in the total and hypertensive subgroup.
Based on the findings, researchers said, " supplementation with 162 mg/d quercetin from onion skin extract lowers ABP in patients with hypertension, suggesting a cardioprotective effect of quercetin".
In other words, supplementation with 162 mg/d quercetin from onion skin extract protects the heart against CVD by normalizing the blood pressure in hypertensive patients through unknown mechanisms.
Taken together, onion may be considered a remedy for the prevention and treatment of liver alcoholic cytotoxicity pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial by Brüll V1, Burak C1, Stoffel-Wagner B2, Wolffram S3, Nickenig G4, Müller C4, Langguth P5, Alteheld B1, Fimmers R6, Naaf S7, Zimmermann BF7, Stehle P1, Egert S. (PubMed)
(2) Molecular mechanisms of the anti-obesity effect of bioactive ingredients in common spices: a review by Lu M, Cao Y , Xiao J, Song M, and Ho CT. (PubMed)
(3) Obesity and hypertension by Shu-Zhong Jiang, Wen Lu, Xue-Feng Zong, Hong-Yun Ruan, and Yi Liu. (PMC)
#Kimchi #Extracts (Fematneted Cabbage) Inhibit Genes Associated with the Risk of Colorectal Cancer, Researchers Suggest
Kyle J. Norton
Colorectum formed part of the secretory system including the large intestine and the rectum is the second part of the digestive system involved in the absorption of water from the small bowel contents and breaks down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
The colon formed part of the large intestine plays a critical role in re-absorbing fluids and processing waste products from the body for elimination.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon
The rectum or the part of the large intestine nearest the rectum plays a temporary storehouse for feces.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is relatively very common and slowly growing and progresses cancer in a predictable way.
The disease is more common in people over the age of 50. Regular colonoscopy after the age of 50 is valuable to detect the disease in the early stage, thereby increasing the rate of survival.
According to the statistics provided by the American Cancer Society, colorectal cancer, including cancer in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the prevention of cancer, researchers examined the effects of commercial kimchi (CK), standardized kimchi (SK), cancer-preventive kimchi (CPK), and anticancer kimchi (ACK), on colorectal carcinogenesis in mice.
Male BALB/c mice induced colon cancer with a single intraperitoneal injection of azoxymethane (AOM, 10 mg/kg body weight) and subsequent treatment with 2% dextran sulfate sodium (DSS) in drinking water for 7 days for two cycles.
According to the experimental analysis.
* Treatment with the methanolic extracts from different kimchis, particularly 1.89 g/kg of ACK, significantly increased colon length, decreased the ratio of colon weight/length, and resulted in the lowest number of tumors compared with the other kimchi-treated groups.
In other words, the kimchi extract protected the colonic cells against the alternation of DNA.
* Injection of ACK was able to suppress AOM- and DSS-induced colonic mucosal damage and neoplasia.
* ACK also significantly decreased the mRNA levels of proinflammatory cytokines (TNF-α, IL-6, and IFN-γ) as well as the mRNA and protein expression of inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) to induce protein, lipid, and cell DNA damage.
* More importantly, kimchi extract enhanced the tumor-suppressive genes on AOM- and DSS-induced colorectal carcinogenesis in the BALB/c mice.
Based on the results, researchers wrote, " The anticancer effects of ACK were particularly potent. Thus, it is possible that the health-promoting sub-ingredients added to ACK might be used to prevent colon carcinogenesis in humans".
Taken together, cabbage may process anti colorectal activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice by Kim HY1, Song JL, Chang HK, Kang SA, Park KY. (PubMed)
Colorectum formed part of the secretory system including the large intestine and the rectum is the second part of the digestive system involved in the absorption of water from the small bowel contents and breaks down of certain materials in the feces into substances of which some of them to be reabsorbed and reused by the body.
The colon formed part of the large intestine plays a critical role in re-absorbing fluids and processing waste products from the body for elimination.
The colon consists of four parts: descending colon, ascending colon, transverse colon, and sigmoid colon
The rectum or the part of the large intestine nearest the rectum plays a temporary storehouse for feces.
Colorectal cancer is a medical condition caused by irregular cell growth in the tissue of the colon or rectum.
Most cases of colorectal cancer start in the cells on the surface of the inner lining in the colon and rectum, before penetrating into deeper layers to form a tumor through proliferation.
Colorectal cancer is relatively very common and slowly growing and progresses cancer in a predictable way.
The disease is more common in people over the age of 50. Regular colonoscopy after the age of 50 is valuable to detect the disease in the early stage, thereby increasing the rate of survival.
According to the statistics provided by the American Cancer Society, colorectal cancer, including cancer in the colon or rectum is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States.
In 2019, approximately 101,420 new cases of colon cancer and 44,180 new cases of rectal cancer will be diagnosed in the US.
The 5-year survival rate of colorectal cancer diagnosed at the localized stage is 90%. Sadly, only 39% of patients are diagnosed at this early stage.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the prevention of cancer, researchers examined the effects of commercial kimchi (CK), standardized kimchi (SK), cancer-preventive kimchi (CPK), and anticancer kimchi (ACK), on colorectal carcinogenesis in mice.
Male BALB/c mice induced colon cancer with a single intraperitoneal injection of azoxymethane (AOM, 10 mg/kg body weight) and subsequent treatment with 2% dextran sulfate sodium (DSS) in drinking water for 7 days for two cycles.
According to the experimental analysis.
* Treatment with the methanolic extracts from different kimchis, particularly 1.89 g/kg of ACK, significantly increased colon length, decreased the ratio of colon weight/length, and resulted in the lowest number of tumors compared with the other kimchi-treated groups.
In other words, the kimchi extract protected the colonic cells against the alternation of DNA.
* Injection of ACK was able to suppress AOM- and DSS-induced colonic mucosal damage and neoplasia.
* ACK also significantly decreased the mRNA levels of proinflammatory cytokines (TNF-α, IL-6, and IFN-γ) as well as the mRNA and protein expression of inducible nitric oxide synthase and cyclooxygenase-2 (COX-2) to induce protein, lipid, and cell DNA damage.
* More importantly, kimchi extract enhanced the tumor-suppressive genes on AOM- and DSS-induced colorectal carcinogenesis in the BALB/c mice.
Based on the results, researchers wrote, " The anticancer effects of ACK were particularly potent. Thus, it is possible that the health-promoting sub-ingredients added to ACK might be used to prevent colon carcinogenesis in humans".
Taken together, cabbage may process anti colorectal activity, pending to the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Kimchi protects against azoxymethane/dextran sulfate sodium-induced colorectal carcinogenesis in mice by Kim HY1, Song JL, Chang HK, Kang SA, Park KY. (PubMed)
#Ginger's 6-Gingerol Inhibits Resistance Proteins Associated with the Onset of Psychological Stress, Scientists Say
Kyle J. Norton
Scientists may have found a pungent spice that improves fat and glucose metabolism under stress, according to studies.
Psychological stress is the expression of emotion and physiology when events happen to an individual going beyond his/her coping ability.
However, the coping resources for coping with the stress of each individual are quite different. Some can cope better than others when dealing with the same unfortunate events.
Psychologic stress was found to induce physiologic responses, leading to physical symptoms and disease. In some cases, the impacts of psychological stress can result in the worsening of individuals' medical conditions.
According to epidemiological studies, chronic psychological stress can cause symptoms of anxiety and nervousness, panic attacks, physical sensations of anxiety, tendencies to predict the worst, conflict avoidance, muscle tension, tremors, headaches, and low/excessive motivation.
If you have experienced some of the above symptoms, you may have chronic psychological stress, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that psychological stress can increase or decrease the production of certain hormones, causing a significant change in one life physically and psychologically, if the change has become chronic.
Dr. Salam Ranabir, the lead scientist in examining the stress impacts on hormones, said, "In the modern environment one is exposed to various stressful conditions. Stress can lead to changes in the serum level of many hormones including glucocorticoids, catecholamines, growth hormone, and prolactin"
And, " Some of these changes are necessary for the fight or flight response to protect oneself. Some of these stress responses can lead to endocrine disorders like Graves’ disease, gonadal dysfunction, psychosexual dwarfism, and obesity. Stress can also alter the clinical status of many preexisting endocrine disorders such as precipitation of adrenal crisis and thyroid storm".
These results suggested clearly that people under long-term stress are susceptible to the onset of abnormal hormone-related diseases and syndromes.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding natural ingredients for the improvement of fat and glucose metabolism examined the effects of individual spices including ginger physiological responses to high-fat meals.
These results strongly suggested that a meal containing a high antioxidant spice blend attenuates postprandial lipemia by 30% compared to a low-spice meal through the influence of acute psychological stress on fat metabolism.
A 2 x 2, randomized, 4-period crossover design in 20 healthy but overweight adults, researchers compared the effects of 14.5 g spices (black pepper, cinnamon, cloves, garlic, ginger, oregano, paprika, rosemary, and turmeric) vs. placebo incorporated into a high-fat meal (1000 kcal, 45 g fat), followed by psychological stress (Trier Social Stress Test) vs. rest on postprandial metabolism.
According to the blood sample collected at baseline and at 105, 140, 180, and 210 minutes for analysis of triglycerides, glucose, and insulin, the levels of serum triglycerides, glucose, and insulin were elevated following the meal.
Application of spices, including ginger reduced post-meal triglycerides by 31% followed by the rest condition (p = 0.048), however, this effect was not presented during stress.
Furthermore, the significant increase in acute stress of the tested subjects also had a strong impact on negating the activity of spice on levels of glucose or insulin.
Moreover, The spice blend and several of the individual spices dose-dependently inhibited PL and PLA2 activity in vitro.
Phospholipase (PL) and Phospholipase A2 (PLA) are associated with the development of stress and inflammation.
Dr. the lead scientist after taking into account co and confounders said, "Spices may attenuate postprandial lipemia via inhibition of PL and PLA2. However, the impact of psychological stress negates any influence of the spice blend on triglycerides, and further, increases blood glucose and insulin".
The finding strongly suggested ginger showed no effects in inhibiting triglycerides and modulating the levels of glucose and insulin in people who are under constant psychological stress.
Interestingly, in order to reveal more information about ginger against psychological stress, researchers evaluated the activity 6-gingerol on C. elegans.
The bioactive compound 6-gingerol was isolated from the most active ethyl acetate soluble fraction of ginger and showed an elevated survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The results were attributed to the 6-gingerol activity in the elevated antioxidant enzyme activities of C. elegans, in the reduction of intracellular reactive oxygen species (ROS) accumulation in worms in a dose-dependent manner.
More importantly, the injection of 6-gingerol demonstrated that the increased stress tolerance of 6-gingerol-mediated worms could result from the promotion of stress resistance proteins such as heat shock protein (HSP-16.2) and superoxide dismutase (SOD-3).
Taken together, ginger exerted significant antioxidative stress through its bioactive compound compared to no effects in modulating triglycerides, blood glucose, and insulin if a person is under acute psychological stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 andDae Keun Kim. (PubMed)
(2) Effects of culinary spices and psychological stress on postprandial lipemia and lipase activity: results of a randomized crossover study and in vitro experiments by Cindy E McCrea, Sheila G West,
Penny M Kris-Etherton, Joshua D Lambert, Trent L Gaugler,Danette L Teeter, Katherine A Sauder, Yeyi Gu, Shannon L Glisan, and Ann C Skulas-Ray. (PMC)
(3) Stress and hormones by Salam Ranabir and K. Reetu. (PMC)
Scientists may have found a pungent spice that improves fat and glucose metabolism under stress, according to studies.
Psychological stress is the expression of emotion and physiology when events happen to an individual going beyond his/her coping ability.
However, the coping resources for coping with the stress of each individual are quite different. Some can cope better than others when dealing with the same unfortunate events.
Psychologic stress was found to induce physiologic responses, leading to physical symptoms and disease. In some cases, the impacts of psychological stress can result in the worsening of individuals' medical conditions.
According to epidemiological studies, chronic psychological stress can cause symptoms of anxiety and nervousness, panic attacks, physical sensations of anxiety, tendencies to predict the worst, conflict avoidance, muscle tension, tremors, headaches, and low/excessive motivation.
If you have experienced some of the above symptoms, you may have chronic psychological stress, please make sure you check with your doctor to rule out the possibility.
Some researchers suggested that psychological stress can increase or decrease the production of certain hormones, causing a significant change in one life physically and psychologically, if the change has become chronic.
Dr. Salam Ranabir, the lead scientist in examining the stress impacts on hormones, said, "In the modern environment one is exposed to various stressful conditions. Stress can lead to changes in the serum level of many hormones including glucocorticoids, catecholamines, growth hormone, and prolactin"
And, " Some of these changes are necessary for the fight or flight response to protect oneself. Some of these stress responses can lead to endocrine disorders like Graves’ disease, gonadal dysfunction, psychosexual dwarfism, and obesity. Stress can also alter the clinical status of many preexisting endocrine disorders such as precipitation of adrenal crisis and thyroid storm".
These results suggested clearly that people under long-term stress are susceptible to the onset of abnormal hormone-related diseases and syndromes.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding natural ingredients for the improvement of fat and glucose metabolism examined the effects of individual spices including ginger physiological responses to high-fat meals.
These results strongly suggested that a meal containing a high antioxidant spice blend attenuates postprandial lipemia by 30% compared to a low-spice meal through the influence of acute psychological stress on fat metabolism.
A 2 x 2, randomized, 4-period crossover design in 20 healthy but overweight adults, researchers compared the effects of 14.5 g spices (black pepper, cinnamon, cloves, garlic, ginger, oregano, paprika, rosemary, and turmeric) vs. placebo incorporated into a high-fat meal (1000 kcal, 45 g fat), followed by psychological stress (Trier Social Stress Test) vs. rest on postprandial metabolism.
According to the blood sample collected at baseline and at 105, 140, 180, and 210 minutes for analysis of triglycerides, glucose, and insulin, the levels of serum triglycerides, glucose, and insulin were elevated following the meal.
Application of spices, including ginger reduced post-meal triglycerides by 31% followed by the rest condition (p = 0.048), however, this effect was not presented during stress.
Furthermore, the significant increase in acute stress of the tested subjects also had a strong impact on negating the activity of spice on levels of glucose or insulin.
Moreover, The spice blend and several of the individual spices dose-dependently inhibited PL and PLA2 activity in vitro.
Phospholipase (PL) and Phospholipase A2 (PLA) are associated with the development of stress and inflammation.
Dr. the lead scientist after taking into account co and confounders said, "Spices may attenuate postprandial lipemia via inhibition of PL and PLA2. However, the impact of psychological stress negates any influence of the spice blend on triglycerides, and further, increases blood glucose and insulin".
The finding strongly suggested ginger showed no effects in inhibiting triglycerides and modulating the levels of glucose and insulin in people who are under constant psychological stress.
Interestingly, in order to reveal more information about ginger against psychological stress, researchers evaluated the activity 6-gingerol on C. elegans.
The bioactive compound 6-gingerol was isolated from the most active ethyl acetate soluble fraction of ginger and showed an elevated survival rate of worms against stressful environments including thermal, osmotic, and oxidative conditions.
The results were attributed to the 6-gingerol activity in the elevated antioxidant enzyme activities of C. elegans, in the reduction of intracellular reactive oxygen species (ROS) accumulation in worms in a dose-dependent manner.
More importantly, the injection of 6-gingerol demonstrated that the increased stress tolerance of 6-gingerol-mediated worms could result from the promotion of stress resistance proteins such as heat shock protein (HSP-16.2) and superoxide dismutase (SOD-3).
Taken together, ginger exerted significant antioxidative stress through its bioactive compound compared to no effects in modulating triglycerides, blood glucose, and insulin if a person is under acute psychological stress.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the Karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Longevity and Stress Resistant Property of 6-Gingerol from Zingiber officinale Roscoe in Caenorhabditis elegans by Eun Byeol Lee,1 Jun Hyeong Kim,1 Chang Wan An,1 Yeong Jee Kim,1 Yun Jeong Noh,1Su Jin Kim,1 Ju-Eun Kim,1 Abinash Chandra Shrestha,1 Ha-Neul Ham,1 Jae-Yoon Leem,1Hyung-Kwon Jo,2 Dae-Sung Kim,2 Kwang Hyun Moon,3 Jeong Ho Lee,3 Kyung Ok Jeong,3 andDae Keun Kim. (PubMed)
(2) Effects of culinary spices and psychological stress on postprandial lipemia and lipase activity: results of a randomized crossover study and in vitro experiments by Cindy E McCrea, Sheila G West,
Penny M Kris-Etherton, Joshua D Lambert, Trent L Gaugler,Danette L Teeter, Katherine A Sauder, Yeyi Gu, Shannon L Glisan, and Ann C Skulas-Ray. (PMC)(3) Stress and hormones by Salam Ranabir and K. Reetu. (PMC)
#Healthyfood #Cabbage Induces Cytotoxicity of Endometrial Cancer Cells, According to Researchers
Kyle J. Norton
The endometrium is the inner lining of the mammalian uterus and is very susceptible to hormone change, particularly in the menstrual cycle.
Endometrial cancer is a chronic condition characterized by irregular cells in the tissue of the endometrium.
It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
Most cases of endometrial cancer start on the cells on the surface of the inner lining of the endometrium. At the advanced stage, after penetrating into the deeper layers, malignant cancer cells may travel a distance away to infect other healthy tissues and organs.
Endometrial cancer has been found to metastasize to the rectum, bladder, pelvic and para-aortic lymph nodes, vagina.
The exact causes of endometrial cancer are unknown. Epidemiological studies suggested that the increase in age, more years of menstruation, never been pregnant, obesity, and the use of hormone therapy are some of the major prevalent risk factors associated with endometrial cancer.
Some researchers indicated that hormone changes in women's bodies such as higher androgen and estrogen levels and lower levels of progesterone due to polycystic.
In the US, endometrial cancer is the most common cancer of the female reproductive organs. Every year, approximately 63,000 new cases of uterus cancer are diagnosed, causing the death of 11,000 women.
The 5-year survival rates for white and black women with the disease are 84% and 62% respectively.
At the invasive stage, the survival rate is 16%.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the treatment of cancer, researchers examined the effects of 3,3'-Diindolylmethane (DIM), a major in vivo product of indole-3-carbinol (I3C), which is a promising anticancer agent derived from vegetables of the Brassica genus including cabbage on the endometrial cancer cell line.
According to the results of the tested analysis,* DIM induced cytotoxic activity by increasing the level of TGF-alpha transcripts by approximately 4-fold within 24 h of indole treatment in the tested cancer cells.
* DIM also induced a 4-fold increase in the activity of the estrogen response marker, alkaline phosphatase (AP), the cancer markers.
In other words, DIM increased the maximum stimulatory effect of estrogen on TGF-alpha expression to induce cancer cell death.
* DIM alone treatment stimulated levels of secreted TGF-alpha protein by >10-fold. More precisely, the elevated addition of TGF-alpha inhibited the growth of Ishikawa cells, whereas incubation with a TGF-alpha antibody partially reversed the growth-inhibitory effects of DIM.
Based on the results, researchers wrote, " ligand-independent estrogen receptor agonist activity of DIM, and uncover an essential role for the stimulation in TGF-alpha expression and the TGF-alpha activated signal transduction pathway in the potent cytostatic effects of DIM in endometrial cancer cells".
Taken together, cabbage may be considered a functional food for the treatment of endometrial cancer pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression by Leong H1, Firestone GL, Bjeldanes LF. (PubMed)
The endometrium is the inner lining of the mammalian uterus and is very susceptible to hormone change, particularly in the menstrual cycle.
Endometrial cancer is a chronic condition characterized by irregular cells in the tissue of the endometrium.
It's the fourth most common cancer among women overall, after breast cancer, lung cancer, and bowel cancer.
Most cases of endometrial cancer start on the cells on the surface of the inner lining of the endometrium. At the advanced stage, after penetrating into the deeper layers, malignant cancer cells may travel a distance away to infect other healthy tissues and organs.
Endometrial cancer has been found to metastasize to the rectum, bladder, pelvic and para-aortic lymph nodes, vagina.
The exact causes of endometrial cancer are unknown. Epidemiological studies suggested that the increase in age, more years of menstruation, never been pregnant, obesity, and the use of hormone therapy are some of the major prevalent risk factors associated with endometrial cancer.
Some researchers indicated that hormone changes in women's bodies such as higher androgen and estrogen levels and lower levels of progesterone due to polycystic.
In the US, endometrial cancer is the most common cancer of the female reproductive organs. Every year, approximately 63,000 new cases of uterus cancer are diagnosed, causing the death of 11,000 women.
The 5-year survival rates for white and black women with the disease are 84% and 62% respectively.
At the invasive stage, the survival rate is 16%.
Cabbage is a species of Brassica oleracea belonging to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
On findings a natural wholefood for the treatment of cancer, researchers examined the effects of 3,3'-Diindolylmethane (DIM), a major in vivo product of indole-3-carbinol (I3C), which is a promising anticancer agent derived from vegetables of the Brassica genus including cabbage on the endometrial cancer cell line.
According to the results of the tested analysis,* DIM induced cytotoxic activity by increasing the level of TGF-alpha transcripts by approximately 4-fold within 24 h of indole treatment in the tested cancer cells.
* DIM also induced a 4-fold increase in the activity of the estrogen response marker, alkaline phosphatase (AP), the cancer markers.
In other words, DIM increased the maximum stimulatory effect of estrogen on TGF-alpha expression to induce cancer cell death.
* DIM alone treatment stimulated levels of secreted TGF-alpha protein by >10-fold. More precisely, the elevated addition of TGF-alpha inhibited the growth of Ishikawa cells, whereas incubation with a TGF-alpha antibody partially reversed the growth-inhibitory effects of DIM.
Based on the results, researchers wrote, " ligand-independent estrogen receptor agonist activity of DIM, and uncover an essential role for the stimulation in TGF-alpha expression and the TGF-alpha activated signal transduction pathway in the potent cytostatic effects of DIM in endometrial cancer cells".
Taken together, cabbage may be considered a functional food for the treatment of endometrial cancer pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cytostatic effects of 3,3'-diindolylmethane in human endometrial cancer cells result from an estrogen receptor-mediated increase in transforming growth factor-alpha expression by Leong H1, Firestone GL, Bjeldanes LF. (PubMed)
#Strawberries Inhibit Genes Associated with the Risk of #Leukemia (CEM), Researchers say
Kyle J. Norton
Scientists may have found a whole food which contains abundantly bioactive compounds for the prevention and treatment of leukemia with no side effects, some studies suggested.
Leukemia is a medical and chronic condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system or the body's blood-forming tissues.
Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
The causes of leukemia are unknown. However, most common risk factors associated with the onset of the disease include radiation exposure, treatment chemotherapy for cancer, smoking, family history of leukemia, and exposure to certain chemicals such as benzene.
Genetic preposition, according to some researchers, also plays a critical role in the prevalent risk of leukemia.
Dr. Nazanin Heidari, the lead scientist in the investigation of the genetic impact in the risk of leukemia wrote, "Epigenetic and genetic alterations are two mechanisms participating in leukemia, which can inactivate genes involved in leukemia pathogenesis or progression".
The team continued, inactivation of the genes ASPP1, TP53, IKZF1, and P15, have been correlated with poor prognosis in acute lymphoid leukemia (ALL), chronic lymphoid leukemia (CLL), chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML), respectively. And abnormal genes specifically involved in leukemogenesis such as chromosomal translocations as well as genetic or epigenetic alterations, are involved in leukemogenesis.
Therefore, people who carry the mutated or inactive genes are at an increased risk of the condition.
Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. The fruits have been grown all over the world with a suitable climate for commercial profits and health benefits.
The major chemical compounds of strawberry include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin
In finding a natural ingredient or whole food for the prevention and treatment of leukemia (CEM), researchers at the Indian Institute of Science evaluated the consumption of berry fruits, including strawberries, against oxidative stress-mediated diseases.
In vivo, the methanolic extract of strawberry (MESB) fruits demonstrated a potential activity against leukemia (CEM) cell lines.
In mice models, the extract of the fruit also displayed cancer therapeutic and chemopreventive potential.
According to the tested assay, MESB induced cytotoxicity in cancer cells, irrespective of origin, through its antioxidant properties in a concentration- and time-dependent manner.
Furthermore, according to the results at the end of the experience, MESB treatment affected tumor cell proliferation by activating apoptosis with no side effects.
In-depth analysis of the effect of the extract, researchers found that MESB induces cancer cell apoptosis through enhancing the function of the tumor suppressor gene p70 in the intrinsic pathway of apoptosis bypassed the mutated tumor suppressor gene p53.
Dr. Somasagara RR, the lead author said, "Strawberry fruits possess both cancer preventive and therapeutic values".
Taken together, strawberries with the abundant bioactive compound may be considered a functional fruit for the prevention and treatment of leukemia (CEM) with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated foShorty Awarded over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC. (PubMed)
(2) Significance of Inactivated Genes in Leukemia: Pathogenesis and Prognosis by Nazanin Heidari, M.Sc,1 Saeid Abroun, Ph.D.,Jessika Bertacchini, Ph.D,3 Tina Vosoughi, M.D,1 Fakher Rahim, Ph.D. and Najmaldin Saki, Ph.D. (PMC)
Scientists may have found a whole food which contains abundantly bioactive compounds for the prevention and treatment of leukemia with no side effects, some studies suggested.
Leukemia is a medical and chronic condition of abnormal increase of white blood cells produced by the bone marrow and/or the lymphatic system or the body's blood-forming tissues.
Depending on the malignant granulocytes or lymphocytes, leukemia is classified into myelogenous or lymphoblastic leukemia.
The causes of leukemia are unknown. However, most common risk factors associated with the onset of the disease include radiation exposure, treatment chemotherapy for cancer, smoking, family history of leukemia, and exposure to certain chemicals such as benzene.
Genetic preposition, according to some researchers, also plays a critical role in the prevalent risk of leukemia.
Dr. Nazanin Heidari, the lead scientist in the investigation of the genetic impact in the risk of leukemia wrote, "Epigenetic and genetic alterations are two mechanisms participating in leukemia, which can inactivate genes involved in leukemia pathogenesis or progression".
The team continued, inactivation of the genes ASPP1, TP53, IKZF1, and P15, have been correlated with poor prognosis in acute lymphoid leukemia (ALL), chronic lymphoid leukemia (CLL), chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML), respectively. And abnormal genes specifically involved in leukemogenesis such as chromosomal translocations as well as genetic or epigenetic alterations, are involved in leukemogenesis.
Therefore, people who carry the mutated or inactive genes are at an increased risk of the condition.
Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. The fruits have been grown all over the world with a suitable climate for commercial profits and health benefits.
The major chemical compounds of strawberry include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin
In finding a natural ingredient or whole food for the prevention and treatment of leukemia (CEM), researchers at the Indian Institute of Science evaluated the consumption of berry fruits, including strawberries, against oxidative stress-mediated diseases.
In vivo, the methanolic extract of strawberry (MESB) fruits demonstrated a potential activity against leukemia (CEM) cell lines.
In mice models, the extract of the fruit also displayed cancer therapeutic and chemopreventive potential.
According to the tested assay, MESB induced cytotoxicity in cancer cells, irrespective of origin, through its antioxidant properties in a concentration- and time-dependent manner.
Furthermore, according to the results at the end of the experience, MESB treatment affected tumor cell proliferation by activating apoptosis with no side effects.
In-depth analysis of the effect of the extract, researchers found that MESB induces cancer cell apoptosis through enhancing the function of the tumor suppressor gene p70 in the intrinsic pathway of apoptosis bypassed the mutated tumor suppressor gene p53.
Dr. Somasagara RR, the lead author said, "Strawberry fruits possess both cancer preventive and therapeutic values".
Taken together, strawberries with the abundant bioactive compound may be considered a functional fruit for the prevention and treatment of leukemia (CEM) with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, Best Before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated foShorty Awarded over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC. (PubMed)
(2) Significance of Inactivated Genes in Leukemia: Pathogenesis and Prognosis by Nazanin Heidari, M.Sc,1 Saeid Abroun, Ph.D.,Jessika Bertacchini, Ph.D,3 Tina Vosoughi, M.D,1 Fakher Rahim, Ph.D. and Najmaldin Saki, Ph.D. (PMC)
#Banana Inhibits Hypertension and Oxidative Stress Related Diseases, Researchers Say
Kyle J. Norton
Scientists may have found an inexpensive whole fruit for the prevention and treatment of hypertension with no side effects, some studies found.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
Hypertension is a medical condition characterized by abnormally high blood pressure. one of the preventable risk factors of heart disease associated with the cluster of metabolic syndrome.
In other words, high blood pressure means raising the pressure in your heart. the condition can be acute or chronic.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
Chronic high blood pressure epidemiologically can damage the arteries and cause blood clots to form in the arteries, blocking the blood flow and contributing to the onset of cardiovascular and neuro diseases.
Although certain chronic conditions such as kidney disease are found to associate with chronic hypertension which can only be treated by addressing the usable condition, the syndrome in the Western world is mostly a result of unhealthy diet and obesity.
According to a joint study led by the Tecnológico de Monterrey, that examined the effects of
Western and Modern Mexican dietary patterns and the incident hypertension in Mexican women, the comparison of participants who followed the diet with loaded heavily with vegetables, fruits and legumes and who follow the Western and Modern Mexican dietary patterns loaded heavily with processed meats, fast foods, and red meat; and finally the third component was loaded heavily with corn tortillas, hot peppers, and sodas suggested that
* The multivariable-adjusted odds of hypertension in the highest quartile of the W pattern were 24% higher than the odds for individuals in the lowest quartile.
* Women in the highest quartile of the MM pattern had 15% higher odds than women in the lowest quartile.
* And The Fruits & Vegetables (FV) pattern was not significantly associated with hypertension.
These results strongly indicated high blood pressure can be prevented by following a healthy diet with high fruits and vegetables, whole grain and low saturated and trans fat, red meat and processed foods.
On finding a natural chemical compound or whole food for the prevention and treatment of hypertension, researchers evaluate the corosolic acid (CRA) antihypertensive activity, a constituent of banana leaves.
The experiment included Six-week-old male SHR-cp rats, an animal model of metabolic syndrome that was fed a high-fat diet containing 0.072% CRA for 14 weeks.
Treatment with CRA lowered blood pressure, which was elevated in control animals, by 10% after 8 weeks, and serum-free fatty acids by 21% after 2 weeks.
Oxidative stress markers thiobarbituric acid-reactive substances and 8-hydroxydeoxyguanosine in the tested animal were also decreased by 27% and 59%, respectively, after 2 weeks.
Furthermore, CRA treatment also reduced the levels of myeloperoxidase markers, 3-nitrotyrosine, and 3-chlorotyrosine, by 38% and 39%, respectively, after 10 weeks, and decreased the levels of high sensitivity C-reactive protein, markers of inflammation, after 6 weeks.
The presence of a marker of inflammation is an indication of inflammation.
These results clearly suggested that CRA ameliorates hypertension, and oxidative stress caused by the inflammation in SHR-cp rats.
Dr. Yamaguchi Y, the lead scientist said, "CRA can be beneficial for preventing atherosclerosis-related diseases that are an increasing health care problem worldwide".
Moreover, In a human study to test the effect of bananas on cold stress-induced hypertension, peak expiratory flow rate, and plasma ACE activity, researchers showed that
*Banana treatment reduced the systolic blood pressure (P < 0.005), diastolic blood pressure (P < 0.025), and mean arterial blood pressure (P < 0.005) during cold stress in healthy volunteers compared to controls.
* There were no significant changes in heart rate and peak expiratory flow rate but only a significant decrease in plasma angiotensin-converting enzyme activity after banana treatment.
Levels of plasma angiotensin-converting enzyme are high in patients with hypertension.
Dr. Sarkar C, the lead scientist said' "Banana decreased the rise of systolic blood pressure and diastolic blood pressure in healthy volunteers subjected to cold stress test without much effect on heart rate and peak expiratory flow rate".
Taken together, a banana may be considered a functional fruit for the prevention and treatment of hypertension with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Corosolic acid prevents oxidative stress, inflammation, and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome by Yamaguchi Y1, Yamada K, Yoshikawa N, Nakamura K, Haginaka J, Kunitomo M.(PubMed)
(2) Effect of banana on cold stress test & peak expiratory flow rate in healthy volunteers by Sarkar C1, Bairy KL, Rao NM, Udupa EG. (PubMed)
(3) Western and Modern Mexican dietary patterns are directly associated with incident hypertension in Mexican women: a prospective follow-up study by Adriana Monge,1,2 Martín Lajous,1,4 Eduardo Ortiz-Panozo,1 Beatriz L. Rodríguez,2,3José Juan Góngora,2 and Ruy López-Ridaura. (PMC)
Scientists may have found an inexpensive whole fruit for the prevention and treatment of hypertension with no side effects, some studies found.
Banana is the common name of a genus of tropical herbaceous plants. It can grow from 3 to 9 m and belongs to the family of the lily and the orchid.
Hypertension is a medical condition characterized by abnormally high blood pressure. one of the preventable risk factors of heart disease associated with the cluster of metabolic syndrome.
In other words, high blood pressure means raising the pressure in your heart. the condition can be acute or chronic.
Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.
Chronic high blood pressure epidemiologically can damage the arteries and cause blood clots to form in the arteries, blocking the blood flow and contributing to the onset of cardiovascular and neuro diseases.
Although certain chronic conditions such as kidney disease are found to associate with chronic hypertension which can only be treated by addressing the usable condition, the syndrome in the Western world is mostly a result of unhealthy diet and obesity.
According to a joint study led by the Tecnológico de Monterrey, that examined the effects of
Western and Modern Mexican dietary patterns and the incident hypertension in Mexican women, the comparison of participants who followed the diet with loaded heavily with vegetables, fruits and legumes and who follow the Western and Modern Mexican dietary patterns loaded heavily with processed meats, fast foods, and red meat; and finally the third component was loaded heavily with corn tortillas, hot peppers, and sodas suggested that
* The multivariable-adjusted odds of hypertension in the highest quartile of the W pattern were 24% higher than the odds for individuals in the lowest quartile.
* Women in the highest quartile of the MM pattern had 15% higher odds than women in the lowest quartile.
* And The Fruits & Vegetables (FV) pattern was not significantly associated with hypertension.
These results strongly indicated high blood pressure can be prevented by following a healthy diet with high fruits and vegetables, whole grain and low saturated and trans fat, red meat and processed foods.
On finding a natural chemical compound or whole food for the prevention and treatment of hypertension, researchers evaluate the corosolic acid (CRA) antihypertensive activity, a constituent of banana leaves.
The experiment included Six-week-old male SHR-cp rats, an animal model of metabolic syndrome that was fed a high-fat diet containing 0.072% CRA for 14 weeks.
Treatment with CRA lowered blood pressure, which was elevated in control animals, by 10% after 8 weeks, and serum-free fatty acids by 21% after 2 weeks.
Oxidative stress markers thiobarbituric acid-reactive substances and 8-hydroxydeoxyguanosine in the tested animal were also decreased by 27% and 59%, respectively, after 2 weeks.
Furthermore, CRA treatment also reduced the levels of myeloperoxidase markers, 3-nitrotyrosine, and 3-chlorotyrosine, by 38% and 39%, respectively, after 10 weeks, and decreased the levels of high sensitivity C-reactive protein, markers of inflammation, after 6 weeks.
The presence of a marker of inflammation is an indication of inflammation.
These results clearly suggested that CRA ameliorates hypertension, and oxidative stress caused by the inflammation in SHR-cp rats.
Dr. Yamaguchi Y, the lead scientist said, "CRA can be beneficial for preventing atherosclerosis-related diseases that are an increasing health care problem worldwide".
Moreover, In a human study to test the effect of bananas on cold stress-induced hypertension, peak expiratory flow rate, and plasma ACE activity, researchers showed that
*Banana treatment reduced the systolic blood pressure (P < 0.005), diastolic blood pressure (P < 0.025), and mean arterial blood pressure (P < 0.005) during cold stress in healthy volunteers compared to controls.
* There were no significant changes in heart rate and peak expiratory flow rate but only a significant decrease in plasma angiotensin-converting enzyme activity after banana treatment.
Levels of plasma angiotensin-converting enzyme are high in patients with hypertension.
Dr. Sarkar C, the lead scientist said' "Banana decreased the rise of systolic blood pressure and diastolic blood pressure in healthy volunteers subjected to cold stress test without much effect on heart rate and peak expiratory flow rate".
Taken together, a banana may be considered a functional fruit for the prevention and treatment of hypertension with no side effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Corosolic acid prevents oxidative stress, inflammation, and hypertension in SHR/NDmcr-cp rats, a model of metabolic syndrome by Yamaguchi Y1, Yamada K, Yoshikawa N, Nakamura K, Haginaka J, Kunitomo M.(PubMed)
(2) Effect of banana on cold stress test & peak expiratory flow rate in healthy volunteers by Sarkar C1, Bairy KL, Rao NM, Udupa EG. (PubMed)
(3) Western and Modern Mexican dietary patterns are directly associated with incident hypertension in Mexican women: a prospective follow-up study by Adriana Monge,1,2 Martín Lajous,1,4 Eduardo Ortiz-Panozo,1 Beatriz L. Rodríguez,2,3José Juan Góngora,2 and Ruy López-Ridaura. (PMC)
#CruciferousVegetables Inhibit Pathways and Enzymes Associated with the Onset and Progression of Bladder Cancer, According to Studies
Kyle J. Norton
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excretes it through the urethra.
Bladder cancer is a medical condition characterized by irregular cell growth in the bladder tissue due to the alternation of DNA.
Most cases of primary bladder cancer start on the cells on the surface of the inner lining. However, after growing large enough, the cancerous cell can spread to other regions in the body through the circulation of fluids and blood.
According to the statistics. 90% of bladder cancer were diagnosed in people who are older than 55. and the average age of people diagnosed with bladder cancer is 73.
Every year, the disease causes over 17,000 deaths, and bladder cancer is the eighth most common cause of cancer death in men.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women.
Usually, it starts from the lining of the bladder and is caused by several types of malignant growths of the urinary bladder cells.
Although there are many risk factors associated with the onset of bladder cancer, long-term cigarette smoking use is considered a significant cause of the disease. Smokers are 4 to 7 times more likely to develop bladder cancer than nonsmokers.
However, most of the cigarette smoker has never developed bladder cancer.
In finding a potential plant that processes anti-cancer activity researchers evaluated the diets rich in cruciferous vegetables, particularly broccoli on bladder cancer risk.
In vitro studies, isothiocyanates, the major chemical compound of cruciferous vegetables inhibited bladder cancer cell lines, induced cell cycle arrest, and apoptosis.
Furthermore, isothiocyanates demonstrated many mechanisms of anticancer activity at the steps of cancer initiation, promotion, and progression.
Moreover, isothiocyanates induced cancer cell death by targeting multiple pathways including the adaptive stress response, phase I/II enzyme modulation, pro-growth, pro-survival, pro-inflammatory signaling, angiogenesis, and even epigenetic modulation, according to multiple in vivo studies.
Collectively, researchers said, "Overall, both cell and animal studies support a potential role for isothiocyanates in bladder cancer prevention and treatment. Future studies must examine clinically relevant outcomes and define guidelines on ameliorating the bladder cancer burden".
Taken together, collard green consists of isothiocyanates that may be considered a functional food for the prevention and treatment of bladder cancer pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous Vegetables, Isothiocyanates, and Bladder Cancer Prevention by Abbaoui B1,2,3, Lucas CR3,4,5, Riedl KM2,5, Clinton SK5,6, Mortazavi A. (PubMed)
The bladder is a hollow elastic organ in the center of the lower abdomen that collects urine from the kidneys and excretes it through the urethra.
Bladder cancer is a medical condition characterized by irregular cell growth in the bladder tissue due to the alternation of DNA.
Most cases of primary bladder cancer start on the cells on the surface of the inner lining. However, after growing large enough, the cancerous cell can spread to other regions in the body through the circulation of fluids and blood.
According to the statistics. 90% of bladder cancer were diagnosed in people who are older than 55. and the average age of people diagnosed with bladder cancer is 73.
Every year, the disease causes over 17,000 deaths, and bladder cancer is the eighth most common cause of cancer death in men.
Bladder cancer is the most common type of cancer that affects men twice as frequently as it affects women.
Usually, it starts from the lining of the bladder and is caused by several types of malignant growths of the urinary bladder cells.
Although there are many risk factors associated with the onset of bladder cancer, long-term cigarette smoking use is considered a significant cause of the disease. Smokers are 4 to 7 times more likely to develop bladder cancer than nonsmokers.
However, most of the cigarette smoker has never developed bladder cancer.
In finding a potential plant that processes anti-cancer activity researchers evaluated the diets rich in cruciferous vegetables, particularly broccoli on bladder cancer risk.
In vitro studies, isothiocyanates, the major chemical compound of cruciferous vegetables inhibited bladder cancer cell lines, induced cell cycle arrest, and apoptosis.
Furthermore, isothiocyanates demonstrated many mechanisms of anticancer activity at the steps of cancer initiation, promotion, and progression.
Moreover, isothiocyanates induced cancer cell death by targeting multiple pathways including the adaptive stress response, phase I/II enzyme modulation, pro-growth, pro-survival, pro-inflammatory signaling, angiogenesis, and even epigenetic modulation, according to multiple in vivo studies.
Collectively, researchers said, "Overall, both cell and animal studies support a potential role for isothiocyanates in bladder cancer prevention and treatment. Future studies must examine clinically relevant outcomes and define guidelines on ameliorating the bladder cancer burden".
Taken together, collard green consists of isothiocyanates that may be considered a functional food for the prevention and treatment of bladder cancer pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, Best Before it's news, the karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for Shorty Award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Cruciferous Vegetables, Isothiocyanates, and Bladder Cancer Prevention by Abbaoui B1,2,3, Lucas CR3,4,5, Riedl KM2,5, Clinton SK5,6, Mortazavi A. (PubMed)
Monday 6 November 2023
#Healthy Chinese Cabbage Inhibits Cancer cell Proliferation Through Its Immunomodulatory Activity., According to Studies
Kyle J. Norton
Cancers are the class of diseases caused by alteration of DNA that initiates healthy cells to grow disorderly and uncontrollably.
At the later stage, the cancerous cells may travel a distance away from the original site to infect healthy cells of other tissue and organs.
Cancers are the second leading cause of death worldwide besides heart diseases.
According to a statistic from the Canada Government, approximately 1 in 2 Canadians will be diagnosed with cancer during their lifetime, and 1 in 4 will die from the disease.
The most common types of cancer in Canada include lung, colorectal, breast, and prostate cancers. These 4 cancers account for half of all cancers diagnosed in Canada.
Believe it or not, 1/4 of cancer deaths are due to lung cancer.
Depending on the type of cancer, people with cancers may experience general and specific symptoms.
The American Cancer Society wrote, "Cancer may also cause symptoms like fever, extreme tiredness (fatigue), or weight loss. Because cancer cells use up much of the body’s energy supply, or they may release substances that change the way the body makes energy from food. Cancer can also cause the immune system to react in ways that produce these signs and symptoms" " Sometimes, cancer cells release substances into the bloodstream that cause symptoms that are not usually linked to cancer. For example, some cancers of the pancreas can release substances that cause blood clots in veins of the legs".
DNA alternation is the major cause of diseases.
Proliferation is a condition of rapid cell multiplication used by cancer cells to grow indefinitely.
Normal cycle multiplication has a limited cell cycle division before being replaced by the new cell.
In cancer cells, the cell cycle division is unlimited
In cancer, antiproliferative activity is a process to inhibits the growth of cancer cells
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
In finding a natural whole food for the treatment of cancer, researchers examined the heterodimeric 13.8 kDa napkin-like polypeptide that has previously been isolated from Chinese cabbage (Brassica parachinensis) seed on leukemia (L1210) cells.
According to the tested analysis, the selected compound stimulated nitrite production by mouse peritoneal macrophages against the tested cells.
In other words, polypeptide blocks the cell cycle division activity by inhibiting cancer cell proliferation.
Furthermore, the tested compound also stimulated the immune macrophages to reduce the viability of leukemia (L1210) cells through its immunomodulatory activity.
More precisely, the heterodimeric 13.8 kDa napkin-like polypeptide processes a strong anti-cancer cell proliferative property.
Taken together, cabbage contains high levels of phytochemicals that process anticancer cell proliferative activities, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The trypsin-inhibitory, immunostimulatory and antiproliferative activities of a napin-like polypeptide from Chinese cabbage seeds by Ng TB1, Ngai PH. (PubMed)
Cancers are the class of diseases caused by alteration of DNA that initiates healthy cells to grow disorderly and uncontrollably.
At the later stage, the cancerous cells may travel a distance away from the original site to infect healthy cells of other tissue and organs.
Cancers are the second leading cause of death worldwide besides heart diseases.
According to a statistic from the Canada Government, approximately 1 in 2 Canadians will be diagnosed with cancer during their lifetime, and 1 in 4 will die from the disease.
The most common types of cancer in Canada include lung, colorectal, breast, and prostate cancers. These 4 cancers account for half of all cancers diagnosed in Canada.
Believe it or not, 1/4 of cancer deaths are due to lung cancer.
Depending on the type of cancer, people with cancers may experience general and specific symptoms.
The American Cancer Society wrote, "Cancer may also cause symptoms like fever, extreme tiredness (fatigue), or weight loss. Because cancer cells use up much of the body’s energy supply, or they may release substances that change the way the body makes energy from food. Cancer can also cause the immune system to react in ways that produce these signs and symptoms" " Sometimes, cancer cells release substances into the bloodstream that cause symptoms that are not usually linked to cancer. For example, some cancers of the pancreas can release substances that cause blood clots in veins of the legs".
DNA alternation is the major cause of diseases.
Proliferation is a condition of rapid cell multiplication used by cancer cells to grow indefinitely.
Normal cycle multiplication has a limited cell cycle division before being replaced by the new cell.
In cancer cells, the cell cycle division is unlimited
In cancer, antiproliferative activity is a process to inhibits the growth of cancer cells
Cabbage is a species of Brassica oleracea belongings to the family Brassicaceae (or Cruciferae), native to the Mediterranean region along the seacoast. The veggie has a short stem with a crowded mass of leaves, usually green but in some varieties, it may be red or purplish.
In finding a natural whole food for the treatment of cancer, researchers examined the heterodimeric 13.8 kDa napkin-like polypeptide that has previously been isolated from Chinese cabbage (Brassica parachinensis) seed on leukemia (L1210) cells.
According to the tested analysis, the selected compound stimulated nitrite production by mouse peritoneal macrophages against the tested cells.
In other words, polypeptide blocks the cell cycle division activity by inhibiting cancer cell proliferation.
Furthermore, the tested compound also stimulated the immune macrophages to reduce the viability of leukemia (L1210) cells through its immunomodulatory activity.
More precisely, the heterodimeric 13.8 kDa napkin-like polypeptide processes a strong anti-cancer cell proliferative property.
Taken together, cabbage contains high levels of phytochemicals that process anticancer cell proliferative activities, pending the confirmation of the larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All rights reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) The trypsin-inhibitory, immunostimulatory and antiproliferative activities of a napin-like polypeptide from Chinese cabbage seeds by Ng TB1, Ngai PH. (PubMed)
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