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Monday, 13 January 2014

Food Therapy - Strawberries and Breast cancer

Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits.
Breast cancer (malignant breast neoplasm) is a cancer that starts in the tissues of the breast either from the inner lining of milk ducts (Ductal carcinoma) or the lobules (Lobular carcinoma) that supply the ducts with milk. there is also rare cases that breast cancer starts in other areas of the breast. In 2010, over 250,000 new cases of breast cancer were expected to be diagnosed in women in the U.S. alone and the risk of getting invasive breast cancer during life time of a women is 1/8.


Nutrients and Chemicals constituents
1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc. 
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.

The benefits
The consumption of berry fruits, including strawberries, has been suggested to have beneficial effects to human health and reduce the risk of chronic diseases. methanolic extract of strawberry (MESB) fruits in treatment of mice bearing breast adenocarcinoma with MESB blocked the proliferation of tumor cells in a time-dependent manner and resulted in extended life span. Other in the study of the anti cancer effects of The berry extracts showed an ability to inhibit the growth of human oral (KB, CAL-27), breast (MCF-7), colon (HT-29, HCT116), and prostate (LNCaP) tumor cell lines at concentrations ranging from 25 to 200 micro g/mL. by increasing inhibition of cell proliferation in all of the cell lines.

The Side effects
1. Some people may beexperience anaphylactoid reaction to the consumption of strawberries

2. Oxalation
Oxalates in high concentration can cause problem for people with kidney diseases.
3. Etc. 

References
(1) Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice.by Somasagara RR, Hegde M, Chiruvella KK, Musini A, Choudhary B, Raghavan SC.(PubMed)
(2) Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro.by Seeram NP, Adams LS, Zhang Y, Lee R, Sand D, Scheuller HS, Heber D.(PubMed)