Non-alcoholic Fatty Liver Disease is defined as a condition of the fatty liver diseases as a result of accumulated of fat in the liver, not caused by abusive alcohol consumption.
Antioxidants have been found to assist the body in selfrepairment of the cell damage caused by oxidative stress in balancing of the electrons. Oxidative stress is found to cause hepatic damage in patients with acute and chronic hepatitis B virus (HBV) infection and these imbalances in some researches were found to be associated in patients with Non alcoholic fatty liver disease (NAFLD). In a prospective study of 29 patients with NAFLD, 25 diseased controls with chronic viral hepatitis, and 23 healthy controls, lipid peroxidation are significantly increased among patients with NAFLD compared to healthy subjects, but there were no significant correlation between histological grading or staging and levels of pro and antioxidants. This study demonstrate that oxidative may be considered as a potential cause in managing patients with Non alcoholic fatty disease.
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(1) Oxidant stress and antioxidant status among patients with nonalcoholic fatty liver disease (NAFLD).