Chronic myeloid leukemia (CML) also known as chronic myelogenous leukemia is a type of leukemia associated with certain blood-forming cells of the bone marrow.
On finding a natural and potential compound for the treatment of chronic myeloid leukemia, researchers examined the Cucurbitacin B (CuB) antiproliferative effects on various leukemia cell lines.
In order to obtain additional information about cucurbitacin B (CuB) anti myeloid leukemia activity, researchers explored the antitumor effect and action mechanism of cucurbitacin B (CuB) on human T-cell leukemia Jurkat cells.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells by Haritunians T1, Gueller S, Zhang L, Badr R, Yin D, Xing H, Fung MC, Koeffler HP. (PubMed)
(2) Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells by Zhu JS1, Ouyang DY, Shi ZJ, Xu LH, Zhang YT, He XH. (PubMed)
(3) Obesity, weight gain, and risk of chronic myeloid leukemia by Strom SS1, Yamamura Y, Kantarijian HM, Cortes-Franco JE. (PubMed)