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Saturday, 18 January 2014

Food Therapy - Strawberries and benign prostatic hyperplasia and prostate cancer


Strawberry is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits. 
Starting at age 40, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Therefore in order to prevent the symptoms of enlarged prostate is to naturally impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate. Prostate Cancer is defined as a condition of the abnormal proliferation of cells in the prostate. 

Nutrients and Chemicals constituents

1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc. 

The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin.
The benefits
Lycopene,  a phytochemical of member of the carotenoid family, found abundantly in tomatoes, tomato-based products, strawberries, and watermelon, has exerted its antioxidant effects in preventing the risk of benign prostatic hyperplasia and prostate cancer. Other strawberry polyphenols has also exerted its cytotoxic effects on prostate epithelial cell line (P21) and two tumour cell lines relative to comparable normal cells from the same tissue derived from the same patient. Unfortunately, in a three RCTs systematic review, found the high risk of bias in two of the three studies and there is insufficient evidence to either support, or refute, the use of lycopene for the prevention of prostate cancer. Similarly, there is no robust evidence from RCTs to identify the impact of lycopene consumption upon the incidence of prostate cancer, prostate symptoms, PSA levels or adverse events.
The Side effects
1. Some people may beexperience anaphylactoid reaction to the consumption of strawberries

2. Oxalation
Oxalates in high concentration can cause problem for people with kidney diseases.
3. Etc.   
(1) Lycopene for the prevention and treatment of benign prostatic hyperplasia and prostate cancer: a systematic review by Ilic D, Misso M.(PubMed
(2) Strawberry polyphenols are equally cytotoxic to tumourigenic and normal human breast and prostate cell lines by Weaver J, Briscoe T, Hou M, Goodman C, Kata S, Ross H, McDougall G, Stewart D, Riches A.(PubMed)
(3) Lycopene for the prevention of prostate cancer by Ilic D, Forbes KM, Hassed C.(PubMed)