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Thursday, 23 November 2017

Food Therapy: Coffee, A linear Association to Reduced Risk and Progression of Parkinson's Disease

By Kyle J. Norton


Intake of coffee caffeine regularly are associated to a significantly attenuated risk of neurodegenerative conditions, particular in the onset of Parkinson's diseases, a recent study suggested.

Parkinson's disease is neuro degenerative disease caused by deficiency of the dopamine and.degeneration of the basal ganglia of the brain, affecting muscular normal function.

Dopamine acted as as a neurotransmitter and a precursor of other substances including epinephrine.
is a compound present in the body involved brain function in the roles of reward-motivated behavior.

The basal ganglia (or basal nuclei) having a strong interconnected with the cerebral cortex, thalamus, and brainstem, as well as several other brain areas, is a group of subcortical neurons, of varied origin, in the brains of vertebrates with function involved primarily processing movement related information such as emotions, motivations, and cognitive functions.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Harvard School of Public Health, Boston, in compared population comprised 47,351 men and 88,565 women free of Parkinson's disease, stroke, or cancer at baseline, caffeine intake is associated to reduced risk and progression of PD, in compared the top and bottom one-fifth men participants. No effect is found for decaffeinate coffee intake regardless to numbers of cup consumed.

Caffeine, a chemical stimulant found abundantly in caffeinated products, including tea and coffee is a class of methylxanthine having a profound impact in central nervous system (CNS).

Interestingly, among women, numbers of caffeinated coffee intake daily have a strong implication in attenuated risk of PD linearly, in compared to lowest intake of moderated intake groups.

Further more, a case-control study conducted in western Washington State in 1992-2000. Incident PD cases (n = 210) and controls (n = 347) with frequency matched on gender and age identified from enrollees of the Group Health Cooperative health maintenance organization, returned questionnaires by participants indicated, consumption of 2 cups/day showed a strong expression in reduced risk of PD.

More importantly, in the review of twenty-six studies included: 7 cohort, 2 nested case-control, 16 case-control, and 1 cross-sectional study, the total relative odd ratio for the association between caffeine intake in low to moderate groups and PD was 0.75.

But, in cohort studies, reduced risk of PD significantly decreased if only women participants were considered.

Researchers, at above study revealed that PD risk is associated to a linear relation between levels of caffeine exposure of relative odd ratio of 0.76, per 300 mg caffeine intake.

Finally, some researchers addressed that, in the concerns of PD patients in expression a significant impairment of dopaminergic neuron transmission, caffeine acted as acts as a nonselective adenosine receptor antagonist may have a profound effect in treatment of PD through adenosine A2A receptors function in regulation of glutamate and dopamine release. 

Taking together, there is no doubt that risk of PD has an extremely inverse association to caffeine intake, particular in moderated drinkers.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Can coffee consumption lower the risk of Alzheimer's disease and Parkinson's disease? A literature review by Wierzejska R1.(PubMed)
92) Prospective study of caffeine consumption and risk of Parkinson's disease in men and women by Ascherio A1, Zhang SM, Hernán MA, Kawachi I, Colditz GA, Speizer FE, Willett WC.(PubMed)
(3) Parkinson's disease risks associated with cigarette smoking, alcohol consumption, and caffeine intake by Checkoway H1, Powers K, Smith-Weller T, Franklin GM, Longstreth WT Jr, Swanson PD.(PubMed)
(4) Association of coffee and caffeine intake with the risk of Parkinson disease by Ross GW1, Abbott RD, Petrovitch H, Morens DM, Grandinetti A, Tung KH, Tanner CM, Masaki KH, Blanchette PL, Curb JD, Popper JS, White LR.(PubMed)

Food Therapy: Beet or Beetroot, A Functional Food in Reduced Risk and Treatment of Inflammatory Bowel Disease


Kyle J. Norton


Beet or Beetroot, may have a potential effect in ameliorated abnormal function of white blood cells such as neutrophils in reduced risk and treatment of inflammatory bowel disease.

Inflammation is a natural process of immune defense to remove injurious agents, cells and tissues from the body.

Inflammatory bowel disease is the boarder term of conditions characterized by chronic inflammation of intestines, including ulcerative colitis and Crohn disease.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the Poznan University of Medial Science, beetroot (Beta vulgaris var. rubra) products and their major component betanin exhibited antioxidant activities against abnormal neutrophils in modulated reactive oxygen species (ROS) production and DNA damage, in healthy subjects.

The efficacy of betanin in reduced reactive oxygen species (ROS) expression is the result of  exerting antioxidant free radical scavenging and neutralizing activities by slowed down or prevented initiation of free radical chain reaction.

Additionally, betanin, as a major phytochemical also ameliorated the elevated ROS expression in promoted oxidative stress which was found to have a strong implication to cause cellular DNA damage. Some researchers suggested that betanin reduced risk of cellular DNA damage.probably through inter influenced the pro apoptotic caspase-3 in the action of release of ROS and apoptotic cell death.

In deed, activities of betanin in attenuated risk of over expression of ROS in induction of DNA also may be an extrinsic way of the phytochemical in exerting anti-inflammatory and potentially cancer preventive activity.

Further analysis and taking into account of other con founders, researchers once again indicated that betanin with concentration of 100 μM for 24 h, inhibited pro inflammatory expression in ulcerative colitis (UC) and Crohn's disease (CD) patients by protecting the digestive tract that can be observed through action in decreased oxidative DNA damage and promoted apoptosis in neutrophils.

In fact, betaine and other phytochemical baicalein have shown to provide various health benefits to organism in many ways, including down-regulation of inflammation against colitis-associated colon tumorigenesis in tested animal.

In case of anti inflammation, both betaine and baicalein also found to demonstrate a magnificent impact in regulation of the pro inflammatory cytokins such as IL-1β, PGE2, and TNF-α in NF-ĸB activation beside activities in inhibited expression of ROS.

Interestingly, in patients with ulcerative colitis, arabino-oligosaccharides (AOS) derived from sugar beet pulp, stimulated Bifidobacterium spp. and Lactobacillus spp. accompanied by a high production of acetate in eliciting anti-inflammatory responses, thus attenuating inflammatory conditions in UC patients.

The observation illustrated that beet may have a potential in acting as prebiotic to enhance the growth of beneficial microorganisms in the intestines, thus reducing.risk of flare-ups in UC patients.

Furthermore, arabino-oligosaccharides (AOS) also showed to elevate the failure of local anaesthesia in inflamed tissues through lowering of intestinal pH

The findings of improved antioxidant in attenuated free radical in induction of DNA and promotion of abnormal expression of neutrophils, as well as acting as prebiotic suggested that beet may be considered as functional food in reduced risk of chronically digestive inflammatory diseases, particularly in inflammatory bowel disease.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) DNA damage and apoptosis in blood neutrophils of inflammatory bowel diseasepatients and in Caco-2 cells in vitro exposed to betanin by Zielińska-Przyjemska M1, Olejnik A2, Dobrowolska-Zachwieja A3, Łuczak M4, Baer-Dubowska W1.(PubMed)
(2) Modulation of Colitis-associated Colon Tumorigenesis by Baicalein and Betaine by Kim DH1, Sung B1, Chung HY1, Kim ND1.(PubMed)
(3) In vitro fermentation of sugar beet arabino-oligosaccharides by fecal microbiota obtained from patients with ulcerative colitis to selectively stimulate the growth of Bifidobacterium spp. and Lactobacillus spp by Vigsnæs LK1, Holck J, Meyer AS, Licht TR.(PubMed)
(4) Anti-inflammatory activity of baicalein in LPS-stimulated RAW264.7 macrophages via estrogen receptor and NF-κB-dependent pathways by Fan GW1, Zhang Y, Jiang X, Zhu Y, Wang B, Su L, Cao W, Zhang H, Gao X.(PubMed)

Wednesday, 22 November 2017

Food Therapy: Dried Peas (Legumes) in Reduced Risk and Treatment of Prostate Cancer

Kyle J. Norton


Intake of Legume, particular dried Peas daily and regularly may reduce risk and treatment of prostate cancer, some scientists suggested.

Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.

Prostate cancer is medical condition characterized by irregular cell growth in the prostate. Over 11.4 million of men will be diagnosed with prostate cancer at some points during their lifetime, according to statistic.

According to the study at the Yamagata University School of Medicine, in the investigated effect of some flavonoids, isolated from fruits, vegetables, and peas in risk of prostate cancer, using human LNCaP prostate cancer cells researchers found that
1. Genistein, a member of group of flavonoids exerted a significant effect in cell cycle arrest at the G2/M phases, attributed to the suppression of cyclin B expression.
2. The suppression of genistein induced the cyclin-dependent kinase inhibitor p21 which plays an important role in cell cycle progression.

The effect of flavonoids to induce prostate cancer cells apoptosis was attributed to suppression of proteins in control the division of cells by activating gcyclin-dependent kinase (Cdk) enzymes in production p21 antibody.

This result may provide additional persuasion for holistic practitioners to ask their prostate problematic clients to add a portion of rich flavonoids foods into their daily diet.

In concerns of the progressive effect of dietary and lifestyle characteristics and implication of risk of prostate cancer, researchers at the Loma Linda University School of Medicine, conducted a study men of completed a detailed lifestyle questionnaire in 1976 with monitored for cancer incidence until the end of 1982. During the 6-year follow-up period, researchers indicated that  180 histologically confirmed prostate cancers were detected among some 78,000 man-years of follow-up.

Further analysis of the returned questionnaire from the subjects, researchers filed the following interesting results
1. Contrast to general belief, age was inversely associated to risk of prostate cancers
2. History of prostate "trouble" was associated with a 60% increase in risk of the cancer development
3. Increased intake of animal product consumption was also associated to increased risk of the cancer

More intrusively, researchers also emphasized that increasing consumption of beans, lentils and peas, ...........were all associated with significantly decreased prostate cancer risk.

The result of findings although suggested that legume may have a positive effect in reduced prostate cancer incidence, it doesn't mean that you can just eat a large portion of such foods everyday and expected the problem will go away. Negative dietary and life style habits sometimes have a strong implication of the outcome.

More importantly, in the study to confirm the effective of common constituents of seeds (rice, beans, and maize) in ameliorated risk of breast, colon, and skin cancers in animals, researchers suggested that antioxidant rich in seeds may play an important role in reduced oxidative stress and ionizing radiation in initiated cancer and cancer progression.

Dr. Thapa D. in response to the effect of antioxidant and risk of prostate cancer, said, "It has also been established that inflammation is a precursor in neoplastic transformation of the prostate". and "Although, a vast body of experimental and clinical evidence shows efficacy of antioxidants as preventive strategies for prostate cancer, there is a lack of consistent agreement in outcomes especially from recent large-scale randomized clinical trials".

The suggestion indicated that other components which have not been discovered may have a significant effect in reduced risk of prostate cancer beside legume antioxidant activities.

Most study of legume in attenuated risk of treatment of prostate cancer are in the experiment state with small sample size and contradiction are expected due to many factors including studied designed, sample chosen, race,  eating habits,......., therefore a large sample and cohost study, taking into account of other con founders are necessary to confirm this validation.

However, with the information findings, it is safe to suggested that adding some portions of legume, such as peas, into your diet may have an profound effect in reduced risk of prostate cancer.


Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effect of flavonoids on cell cycle progression in prostate cancer cells by Kobayashi T1, Nakata T, Kuzumaki T.(PubMed)
(2) Cohort study of diet, lifestyle, and prostate cancer in Adventist men by Mills PK1, Beeson WL, Phillips RL, Fraser GE.(PubMed)
(3) Protease inhibitors: possible anticarcinogens in edible seeds by Troll W, Wiesner R.(PubMed)
(4) Antioxidants for prostate cancer chemoprevention: challenges and opportunities by Thapa D1, Ghosh R.(PubMed)

Alternative Therapy: Yoga and Your Heart

Kyle J. Norton

Yoga may have a profound effect in improved heart rate regardless to patients precondition,some institution studies suggested

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

According to the study to examine the effects of an 8-week yoga program on heart rate variability and mood in generally healthy women (n=52) randomly assigned to a yoga(vcomprised a 60-minute session twice a week. Each session consisted of breathing exercises, yoga pose practice, and supine meditation/relaxation) group or a control group, in compared to control, yoga group expressed insignificant change in heart rate.

But after taking into account of other con founders, researchers insisted that long term yoga lessons may have a positive effect in heart rate in women with higher levels of stress and trait anxiety.

Other researchers in the concern of the effect of yoga in reduced high blood pressure but not heart rate launched an investigation of 26 male volunteers assigned either in yoga with assessment taken at 3 time points: Pre (5 minutes), during (15 minutes; for ANYB or BAW) and Post (5 minutes)
1. Yoga group expressed a significant decrease (repeated measures ANOVA) in systolic BP and respiration rate
2. Breath rate was found to be difference in all 3 intervals, measured by awareness (BAW) assay.

Further assessment, Dr. Telles S, the led author suggested that the vagal activity involved in heart rate regulation increased during and after ANYB, may contribute to the decrease in BP and changes in the HRV.

More importantly, in a randomized clinical trials (RCTs) in compared yoga against any type of control intervention in healthy individuals or patients with any medical condition, through searching the literature published online database wit 14 studies satisfied the criteria selected, researchers found that
1. Yoga intervention expressed in Ten RCTs showed favourable effects of yoga on various domains of HRV,
2. The meta-analysis (MA) of two trials did not show the favourable effects of yoga compared to usual care.

After taking into account of other influences, researchers suggested that there was no convincing evidence for the effectiveness of yoga in modulating HRV in patients or healthy subjects. 

The information finding, although showed a contradictory results of yoga in improved heart rate, some researchers insisted that long term intervention may prove the differences

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of Yoga on Heart Rate Variability and Mood in Women: A Randomized Controlled Trial by Chu IH1, Lin YJ1, Wu WL1, Chang YK2, Lin IM3.(PubMed)
(2) Blood pressure and heart rate variability during yoga-based alternate nostril breathing practice and breath awareness by Telles S1, Sharma SK1, Balkrishna A1.(PubMed)
(3) Yoga for Heart Rate Variability: A Systematic Review and Meta-analysis of Randomized Clinical Trials.by Posadzki P1, Kuzdzal A, Lee MS, Ernst E.(PubMed)

Tuesday, 21 November 2017

Food Therapy: Vegetables and Fruits Intake > 9 Servings Daily In Reduced Risk of Pancreatic cancer

Kyle J. Norton


Intake of Vegetables and Fruits daily and regularly may reduce risk of pancreatic cancer, some renowned institute studies suggested.


Pancreas cancer is a medical condition characterized by uncontrollable cells growth in the pancreas.
at the late stage, the cancer cells may travel to infect other organs and tissues distanced away from the original site. And it is considered as one of most devastating and rapidly fatal cancer.

According to the statistic, the risk of pancreatic cancer, in population is 1.4% with 44000 new cases
diagnosed every year in US alone.

In the investigate the data  of 532 cases of pancreatic cancer, in patients examined between 1995 and 1999 and to clarify the substantial risk of pancreatic cancer, in this group of subjects, the University of California San Franciscoconducted a population-based case-control study to determine the association between vegetables and fruits and pancreatic cancer, with matching 1,701 age- and sex controls. After considering other con founders, researchers filed the following results
1. Intake of more than 9 serving of vegetables and fruit daily showed a substantially reduced risk of pancreatic cancer,in compared to control group.
2. The relative prevalence of pancreatic cancer, was reduced to .49 
3. Intake of bean score a highest relative odd ration of .46 in compared to intake of other vegetables and fruits intake group.

Further analysis of the returned questionnaire, researchers also indicated that risk of pancreatic cancer, reduced substantially to group with intake of more than 9 severing daily in compared group consuming less than five servings per day of total vegetables and fruits.

In support of the above differentiation, researchers at the Mayo Clinic, also conducted a study to examine the risk of pancreas cancer in fruit, vegetable, fiber, and grain consumption of 384 rapidly ascertained cases and 983 controls (frequency matched on age (±5 years), race, sex, and residence), after analyzing the returned completed epidemiological surveys and 144-item food frequency questionnaires, researchers, after adjusting for diabetes or total sugar intake, indicated that in compare to highest to lowest quintiles, intake of citrus, melon, and berries, other fruits, dark green vegetables, deep yellow vegetables, tomato, other vegetables, dry bean and pea, insoluble fiber, soluble fiber daily had a strong effect in reduced risk of pancreatic cancer,.

Additionally the study also emphasized that increased intake of non-whole grains product is associated to positive risk of pancreatic cancer development. In other word, lower intake of fruits, vegetables, whole grains, and fiber is associated to pancreatic cancer risk.

Although the study did not directly address the health benefits of dried peas in reduced risk of pancreatic cancer, it is safe to suggested that as a member of bean group, dried peas may induce the same relative odd ratio in compare to control.

More interestingly, in a prospective study of fatal pancreas cancer among 34,000 California Seventh-day Adventists between 1976 and 1983(40 deaths from pancreatic cancer, occurred during the follow-up period) to evaluate whether raw fruits and vegetables consumption has been consistently associated with decreased risk of pancreatic cancer,. after analysis the dietary habits and medical history of all the patients record, researchers insisted that
1. Increasing consumption of vegetarian protein products, beans, lentils, and peas as well as dried fruit was associated with highly significant protective relationships to pancreatic cancer, risk.
2. Premedical condition also increase risk of pancreas cancer
3. Patients with history of surgery for peptic or duodenal ulcer were also at risk of pancreatic cancer development.

The findings suggested that regardless to medical condition and prehistory of surgery, intake of vegetables and fruits daily have a profound effect in reduced risk of cancer incidence in compare to non consuming group.

Dr. Mills PK, the lead author said, "the protective relationships associated with frequent consumption of vegetables and fruits high in protease-inhibitor content are more important than any increase in pancreas cancer risk attendant on frequent consumption of meat or other animal products".

Taking altogether, increasing intake of vegetables and fruits and reducing intake of meat and animal product  daily are necessary to ensure the less prevalence of risk of pancreatic cancer.


Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Vegetable and fruit intake and pancreatic cancer in a population-based case-control study in the San Francisco bay area by Chan JM1, Wang F, Holly EA.(PubMed)
(2) Fruit and vegetable consumption is inversely associated with having pancreaticcancer by Jansen RJ1, Robinson DP, Stolzenberg-Solomon RZ, Bamlet WR, de Andrade M, Oberg AL, Hammer TJ, Rabe KG, Anderson KE, Olson JE, Sinha R, Petersen GM.(PubMed)
(3) Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists by Mills PK1, Beeson WL, Abbey DE, Fraser GE, Phillips RL.(PubMed)

Herbal Therapy: Green tea, in Reduced Risk and Treatment of Alzheimer's disease

Kyle J. Norton

Green tea may an integrated form of treatment for patient with Alzheimer's disease through many mechanisms, a recent study proposed.

Green tea, considered as a functional food, linking numbers of health benefit has been reported by several renowned research and studies. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But a slice of ginger in the drink will neutralize the yin over expression in green tea.

Alzheimer's disease is a neuro-degenerative condition of loss or decrease of cognitive and memory functions due to aging.

According to the Maternal and Infant Health, ASL NA 3 SUD, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG), found in green tea exerted a strong anti-inflammatory and anti oxidative properties in protection against neuronal damage and brain edema.

The study also stated that green tea may also contribute to reduced risk and treatment of AD by ameliorated chronic viral infection, one of the cause in responsible for AD's neuropathology.

Dr. Mandel SA. the lead author and expert in green tea study said, "tea drinking may decrease the incidence of dementia, AD, and PD. In particular, its main catechin polyphenol constituent (-)-epigallocatechin-3-gallate (EGCG) has been shown to exert neuroprotective/neurorescue activities in a wide array of cellular and animal models of neurological disorders".

Other researchers suggested that the efficacy of  epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) in reduced risk of AD may be attributed to
1. The antioxidant activity in ameliorate production of ROS in induced risk of oxidative stress which has been found to associate to production of lipid peroxidation, leading to abnormal deposition of amyloid β (Aβ) peptide
2. Free radical over expression in aging people also vulnerable to imbalance of antioxidant and ROS
may have a negatively direct interaction with proteins, nucleic acids, and other molecules and may also alter their structures and functions in inducing risk AD.

Indeed, as a single ingredient isolated from green tea, epigallocatechin and gallic acid, (-)-Epigallocatechin-3-Gallate (EGCG) have been found to cause toxicity in some cases in medical literature. Therefore taking the ingredient in long term and overdoses may have a implication of liver damage.

In a animal study to evaluate the efficacy of Caffeic acid in AD, mice rats randomly divided into three groups: i) control group, ii) AD model group and iii) caffeic acid group, mice fed with the phytochemical expressed a significant in increased learning deficit and cognitive function demonstrated by the Morris water maze task in compared control.

Additionally, fed mice also displayed of attenuated oxidative stress, inflammation, nuclear factor‑κB‑p65 protein expression involved inflammatory cytokins production and suppressed caspase‑3 activity induced cell death and other mechanisms in the rats with AD.

Interestingly, inflammatory process has shown to have an negative role in increased risk of AD, by causing neuroinflammation, including brain cells such as microglia and astrocytes and subsequently in promoted dysfunction and neuronal death. Therefore by suppressing production of inflammatory cytokins, caffeic acid expressed a significant reduction of AD risk.

The efficacy in contribution of cognitive improvement following caffeic acid application may be due to its antioxidant activity and restoration of cholinergic functions, as deficiency of cholinergic function has shown to effect cognition, behavior and activities of daily living

Taking altogether, there is no doubt that green process a neuro protective against the risk and progression of patients with Alzheimer's disease (AD) attributed to some of the major chemical constituents. But intake of single ingredient isolated from green tea should be taken with care.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) The efficacy of Epigallocatechin-3-gallate (green tea) in the treatment of Alzheimer's disease: an overview of pre-clinical studies and translational perspectives in clinical practice by Cascella M#1, Bimonte S#1, Muzio MR2, Schiavone V3, Cuomo A1.(PubMed)
(2) Simultaneous manipulation of multiple brain targets by green tea catechins: a potential neuroprotective strategy for Alzheimer and Parkinson diseases by Mandel SA1, Amit T, Weinreb O, Reznichenko L, Youdim MB.(PubMed)
(3) Effects of caffeic acid on learning deficits in a model of Alzheimer's disease by Wang Y1, Wang Y2, Li J1, Hua L3, Han B1, Zhang Y1, Yang X3, Zeng Z3, Bai H3, Yin H1, Lou J3.(PubMed)
(4) Caffeic acid attenuates oxidative stress, learning and memory deficit in intra-cerebroventricular streptozotocin induced experimental dementia in rats by Deshmukh R1, Kaundal M2, Bansal V2, Samardeep2(PubMed).

Monday, 20 November 2017

Food Therapy: Beet, The Best in Prevention and Treatment of Bladder Cancer

By Kyle J. Norton

Intake of function food beet root regularly not only lowers the early occurrence but also provides a natural treatment of  bladder cancer without inducing adverse effects.

Bladder cancer is a medical condition characterized by irregular cell growth and multiplied disorderly and uncontrollably in bladder tissues.

Beet, best known as the beetroot or garden beet and belonging to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to University of Urbino 'Carlo Bo', betaxanthins and betacyanins, isolated from beet root exerted a significant anti cancer effects in testing bladder cancer cell lines, through expression of antioxidant and pro apoptotic activities.

The anti cancer property of beet root also displayed a strong anti angiogenesis by blocking the cancer cell in established new blood vessel signalling.

When used combination with Vitexin-2-O-xyloside, an apigenin flavone glucoside, betaxanthins and betacyanins also exerted a strong antiproliferative activity in bladder cancer cell lines, intrinsically and extrinsically in expression of apoptosis.

The study also indicated that these combination when used conjunction in  the conventional chemotherapy not only enhanced the effectiveness of treatment in bladder cancer but also overcome the adverse effect of  toxicity and multidrug resistance of cancer cells.

Furthermore, in other study conducted by the same university, Betacyanins (BC) purified from beetroot (Beta vulgaris var. rubra L.) tested,alone or in combination with vitexin-2-O-xyloside (XVX) also isolated from the same vegetable enhanced the ability to reduce the proliferation rate in T24 bladder cancer cells, synergistically.by inhibition of protein of gene in promoted cell survival and enhanced cancer apoptosis.

Taking together, a diet enriched with these bioactive molecules of beet root could be used as function food in prevention and treatment of human bladder cancer.



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)
(2) Betacyanins enhance vitexin-2-O-xyloside mediated inhibition of proliferation of T24 bladder cancer cells by Scarpa ES1, Emanuelli M2, Frati A1, Pozzi V2, Antonini E1, Diamantini G1, Di Ruscio G3, Sartini D3, Armeni T3, Palma F1, Ninfali P1.(PubMed)
(3) C-Glycosyl Flavonoids from Beta vulgaris Cicla and Betalains from Beta vulgaris rubra: Antioxidant, Anticancer and Antiinflammatory Activities-A Review by Ninfali P1, Antonini E1, Frati A1, Scarpa ES1.(PubMed)

Alternative Therapy: Yoga In Regulation of Gene Expression of Related Diseases

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Yoga intervention may have a potential effect in regulated gene expression in some related diseases, researchers at the University of Oslo suggested.

Mutated gene expression included many factors, most common factors are
1. Gene mutation inherited from gene defect parents
2. Gene expression may be altered in the process of regulatory sequences and the transcription factors, cofactors, chromatin regulators and noncoding RNAs
3. Gene mutation is a natural process to protect existence of human beings. Unfortunately, the process in some cases may produce certain subgroups who are vulnerable and susceptible to some diseases.

Biologically, unnatural causes of gene expression due to prolonged exposure to certain harmful agents such as environment toxins, long term used of single or multi ingredients medication,... may also induce genetic change to the negative ways.

Diseases caused by mutated gene expression, include cancer, autoimmunity, neurological disorders, diabetes...

Yoga, the ancient technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to investigate whether the effects on the mind-body system in increased wellness and supported the healing process from diseases, researchers found that yoga intervention not only improved psychological and physiological functioning but also may have regulated effect in gene expression profiling in circulating immune cells, particularly in the molecular level.

Indeed, yoga can improve immunity through a sequence of post in strengthening the body and relaxing the mind. Some believed that by strengthening the body and relaxing the mind, yoga acted as regulators of gene expression in innate and adaptive cell of immune system, through noncoding RNAs, thus reducing risk of inflammatory and auto immune diseases.

In further exploration of the yoga effect in gene expression in the molecular level, researcher at the joint study led by the Coventry University, postulated that mind-body interventions (MBIs) showed a significantly reverse expression of genes involved in inflammatory reactions induced by stress.

Yoga, a mind-body practice of physical poses, controlled breathing, and meditation or relaxation has been best known to reduce implication of stress in increased production of inflammatory cytokins in gene expression, including interleukin-1 (IL-1) and tumor necrosis factor alpha (TNF alpha), thus reducing risk of inflammatory diseases.

And after examined the changes in gene expression that occur after MBIs and to explore how these molecular changes are related to health, through searching the data base of published literature from PubMed throughout September 2016, researcher indicated that over all studies selected indicated an association of gene changes in yoga intervention was a result downregulation of nuclear factor kappa B pathway.

Furthermore, MBI practices may lead to a reduced risk of inflammation-related diseases, through the reduced effects of chronic stress on gene expression.

Most interestingly, in the assessed possible rapid changes in global gene expression profiles in the peripheral blood mononuclear cells (PBMCs) in healthy people practiced either a comprehensive yoga program or a control regimen, researchers found that SK&P program has a more rapid and significantly greater effect on gene expression in PBMCs compared with the control regimen.

Peripheral blood mononuclear cell (PBMC) include lymphocytes (T cells, B cells, NK cells) ,monocytes and granulocytes which play an important role in improved immune system cellular function in fighting against infection and inflammation, enhanced tissue regeneration, restored function due to injure, .....

Truly, the impact of yoga in protection of gene expression of immune system may involve a complexity of simple gene regulatory networks (GRNs), including the gene expression in PBMCs and inflammatory cytokins

Taking altogether, Yoga intervention and related practices may have a profound effect in gene expression alterations through a complex networks of simple gene regulation in the immune system.


Sources
(1) Regulation of gene expression by yoga, meditation and related practices: a review of recent studies by Saatcioglu F1(PubMed)
(2) Rapid gene expression changes in peripheral blood lymphocytes upon practice of a comprehensive yoga program by Qu S1, Olafsrud SM, Meza-Zepeda LA, Saatcioglu F.(PubMed)
(3) What Is the Molecular Signature of Mind-Body Interventions? A Systematic Review of Gene Expression Changes Induced by Meditation and Related Practices by Buric I1,2, Farias M1, Jong J1, Mee C3, Brazil IA1,2,4,5.(PubMed)

Sunday, 19 November 2017

Herbal Therapy: Green Tea, The Liver Protective Functional Food

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Please note that the article does not embrace the use of single and multi ingredients extracted from green tea, particularly in the overdose state.

The use of plants for healing purposes has been predated long before the existence of modern medicine. Herbal plants have formed a fundamental source for conventional medicine in discovery of single ingredient medication, including aspirin (from willow bark), quinine (from cinchona bark), and morphine (from the opium poppy)......

Green tea may have a  potentially hepoprotective effect in prevention and treatment of liver disease, renowned institutes postulated.

Liver disease is a reduced function in toxin elimination of liver as a result of damage or injure, causing by medication, viral infection,....

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory.

According to the joint study lead by theZhujiang Hospital of Southern Medical University Guangzhou, in the review of the data base of PubMed, CNKI, Wanfang and Weipu databases, regular green tea drinking is associated to a significant reduction in the risk of liver disease, including hepatocellular carcinoma, liver steatosis, hepatitis, liver cirrhosis and chronic liver disease.

 Also, Green tea demonstrated a reduced risk of liver disease regardless of the race and geography of the patients resided such as Asian, American and European subgroups.

Unfortunately, in a mouse model, different doses of GT fractions and EGCG and a single dose of lipopolysaccharide (LPS) combined with EGCG, administered for 5 days to mice suggested that mice fed with combining a single high dose of EGCG with a single dose of LPS showed to induce liver injury.

Repeat injection of EGCG in the group also found to associate to mild liver injure, probably was attributed to the adverse effect of lipopolysaccharide (LPS), the study insisted.

Epigallocatechin Gallate (EGCG) is one of the major and powerful antioxidant of green tea found to  be most effective cancer chemopreventive polyphenol in many studies posted on medical literature. However, the single ingredients extract has also been found to induce hepotoxocity and acute liver dysfunction in many occasions due to overdoses and long term usages.

Additionally, according to the Baylor College of Medicine and  Dalhousie University, Halifax reported, "(There is) a case of acute impending liver failure in an adolescent male using a weight-loss product containing green tea extract" and "acute liver toxicity observed in individuals consuming supplements containing green tea extract".

Taking altogether, the conflict result of green tea in liver disease may be result of study design, group selection, sample size, doses intake,........People with liver disease should talk to a specialist of herbal products before consuming.



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic 
Impact In Rice, Pasta, And Potatoes In Half

Sources
(1) The effect of green tea intake on risk of liver disease: a meta analysis by Yin X1, Yang J2, Li T3, Song L4, Han T5, Yang M1, Liao H1, He J1, Zhong X1.(PubMed)
(2) Effect of green tea and its polyphenols on mouse liver by Saleh IG1, Ali Z, Abe N, Wilson FD, Hamada FM, Abd-Ellah MF, Walker LA, Khan IA, Ashfaq MK.(PubMed)
(3) Green tea extract: a potential cause of acute liver failure by Patel SS1, Beer S, Kearney DL, Phillips G, Carter BA.(PubMed)
(4) Acute liver failure induced by green tea extracts: case report and review of the literature by Molinari M1, Watt KD, Kruszyna T, Nelson R, Walsh M, Huang WY, Nashan B, Peltekian K.(PubMed)
(5) Effect of epigallocatechin gallate on uncoupling protein 2 in acute liver injury by Mohammad H Jamal,1,* Hamad Ali,2 Ali Dashti,2 Jasim Al-Abbad,1 Husain Dashti,1 Chako Mathew,2 Waleed Al-Ali,3 Sami Asfar1(PubMed)

Food Therapy: Coffee, The Anti Edema Therapeutic Beverage

By Kyle J. Norton


Good news for coffee drinkers, coffee may have a potential effect in reduced risk and treatment of edema, a recent study suggested.

Edema is a condition characterized by excess fluid retained in body's tissues, inducing swelling.

Coffee, becoming a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study lead by the Kyung Hee University, chlorogenic acid (CGA) isolated from coffee exerted protective effects of transient middle cerebral artery occlusion (tMCAo) rat model in ameliorated brain infarct volume and brain water content.

Chlorogenic acid (CGA) found abundantly in roasted coffee through expression of ester of caffeic acidand (−)-quinic acid, is an powerful antioxidant with profound effect in induced weight loss and edema.

Middle cerebral artery is a carotid artery supplied blood to the brain region involved the primary motor and sensory areas of the face, throat, hand and arm, and in the dominant hemisphere, the areas for speech.

The protective effect in reduced on ischemia-induced neuronal damage and brain edema.is attributed to dihydrocaffeic acid (DHCA), formed in metabolism of CGA in inhibited enzymes involved in the degradation of the extracellular matrix, namely MMP2 and MMP-9. in providing structural and biochemical support to the surrounding cells.

Dihydrocaffeic acid (DHCA) is a metabolite of caffeic acid with potent antioxidant properties.

Matrix metalloproteinase-2  and 9, (MMP-2 - 9) are enzymes with function in activated extracellular matrix (ECM), a collection of extracellular molecules secreted by cells to support the structure of cell. Over expression of MMP-2 and MMP-9 are found to associate to increased risk of disease progression, including arthritis and cancers.

In a rat model of transient middle cerebral artery occlusion, CGA directly showed a significantly reduced brain water content, by the inhibitory effects on MMP-2 and MMP-9 activities.

The study also addressed that the attenuation of brain edema may also be resulted by the chemical compound's anti lipid peroxidation (LPO) activity through increased antioxidant expression.

Lipid peroxidation (LPO) is a free radical-related process occurred under enzymatic control, through the activity of oxidative degradation of lipids.

Other study in the investigation of anti-inflammatory activity against carrageenan, PGE(2) and serotonin-induced hind paw edema and 12-O-tetradecanoyl-13-acetate (TPA)-induced mouse ear edema models, chlorogenic acid (CGA), also exerted a significant anti-inflammatory and antinociceptive activity against serotonin-induced hind paw edema and TPA-induced mouse ear edema, researchers at the Gazi University postulated.

Carrageenan is a mixture of polysaccharides extracted from red and purple seaweeds.

Prostaglandin E2 (PGE2) is a conventional medicine used for treatment of pain and inflammation in numbers of disease, including rheumatoid arthritis and osteoarthritis.

12-O-Tetradecanoylphorbol-13-acetate is one of chemical compound used in experiment to induce endogenous superoxide production. In other word, it is a chemical used routinely in enhanced free radical expression for researcher in animal models.

Finally, researchers in the concerns of the caffeine in reduced risk of edema strongly insisted that injection of caffeine induced diminution in the amount of edema in the body cavities was a result of an inhibition of the production of edema and not to an increased absorption of fluid from the serous body cavities.

The findings suggested that coffee may be used as functional and therapeutic beverage for reduced risk and treatment of edema, more studies are necessary to confirm the promising validity.


Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Protective Effects of Dihydrocaffeic Acid, a Coffee Component Metabolite, on a Focal Cerebral Ischemia Rat Model by Lee K1, Lee BJ2, Bu Y3.(PubMed)
(2) Chlorogenic acid ameliorates brain damage and edema by inhibiting matrix metalloproteinase-2 and 9 in a rat model of focal cerebral ischemia by Lee K1, Lee JS, Jang HJ, Kim SM, Chang MS, Park SH, Kim KS, Bae J, Park JW, Lee B, Choi HY, Jeong CH, Bu Y.(PubMed)
(3) Ethnopharmacological evaluation of some Scorzonera species: in vivo anti-inflammatory and antinociceptive effects by Küpeli Akkol E1, Bahadır Acıkara O, Süntar I, Ergene B, Saltan Çitoğlu G.(PubMed)
(4) STUDIES IN EDEMA : VIII. THE INFLUENCE OF CAFFEINE ON ABSORPTION FROM THE PERITONEAL CAVITY AND THE INFLUENCE OF DIURESIS ON EDEMA by Fleisher MS1, Loeb L.(PubMed)

Saturday, 18 November 2017

Alternative Therapy: Yoga, the Best for Treatment of Patients with Lower Back Pain

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

A recent joint study suggested that yoga participants with chronic lower back pain display a significant improvement on pain intensity in compared to non yoga treatment group.

Yoga is a ancient practical technique of India, included breath control, meditation, bodily movement and gesture,..... with an aim to achieve harmonization of the body, mind, and spirit.

Low back pain is a Musculoskeletal disorders (MSDs) of degenerative disc disease, affecting over 80% of the population in US alone some points in their life.with pain persisted for longer than 3 months,

In a randomized to either yoga or delayed yoga treatment of 150 military veterans in 2013-2015 with outcomes assessed at baseline, 6 weeks, 12 weeks, and 6 months, group attend yoga lessons expressed a greater reductions in Roland-Morris Disability Questionnaire scores than delayed treatment participants at 6 months.

Roland-Morris Disability Questionnaire scores (RMQ) is a questionnaire of 24-item patient-reported outcome and measurement about pain-related disability, in this case, it is lower back pain.

The study also found that treatment group displayed improved more on pain intensity and reduced opioid usage at 12 weeks and at 6 months in compared to delay group.

Opioid is a pain reliever with function to binds to one or more of the three opioid receptors of the body, thus reducing pain.

Dr. Groessl EJ, the lead author said, " Yoga improved health outcomes among veterans despite evidence they had fewer resources, worse health, and more challenges attending yoga sessions than community samples studied previously".

Other, in a parallel randomized controlled trial comparing yoga to education for 120 Veterans with chronic low back pain, yoga treatment group addressed a great positive effects in improved pain score measured by the Defense and Veterans Pain Rating after 24 weeks.

The Defense & Veterans Pain Rating Scale (DVPRS) is a graphic tool of 1-10 McGill pain scale, used to facilitate self-reported pain diagnoses from patients.

Furthermore, the study also found that continuous yoga participation after study not only benefits on physical pain but also showed improved psychological comorbidities.

In support to the above differentiation, the 95 adults recruited from an urban safety-net hospital and five community health centers comparing once-weekly (n = 49) versus twice-weekly (n = 46) standardized yoga classes supplemented by home practice study insisted that there was no differences between once-weekly and twice-weekly groups for pain reduction, but at the 12 weeks, groups with once-weekly or twice-weekly yoga classes exerted the similarly significant efficacy in pain reduction in both group of adults with moderate to severe chronic low back pain.

Truly, evidences in the working population with non-specific low-back pain participated in kundalini yoga at least two times a week, strongly support the effect of yoga in inhibited pain symptom with a significantly reduction in sickness absenteeism.

Kundalini Yoga (kuṇḍalinī-yoga), also known as laya yoga or "the yoga of awareness" is a form of technique used to build physical vitality and increase consciousness through movement, dynamic breathing techniques, meditation, and the chanting of mantras in aid concentration in meditation.


Taking together, yoga may be one of alternative treatment of ancient techniques having a potential effect in reduced pain in patients with lower back pain, please make sure you mention your specific limitation to your instructor before commencing.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

FOOD HACK for Weight Loss
A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Yoga for Military Veterans with Chronic Low Back Pain: A Randomized Clinical Trial by Groessl EJ1, Liu L2, Chang DG3, Wetherell JL4, Bormann JE5, Atkinson JH4, Baxi S6, Schmalzl L7.(PubMed)
(2) Yoga versus education for Veterans with chronic low back pain: study protocol for a randomized controlled trial by Saper RB1, Lemaster CM2, Elwy AR3,4, Paris R5, Herman PM6, Plumb DN7, Sherman KJ8,9, Groessl EJ10,11, Lynch S12, Wang S7, Weinberg J13.(PubMed)
(3) Comparing Once- versus Twice-Weekly Yoga Classes for Chronic Low Back Painin Predominantly Low Income Minorities: A Randomized Dosing Trial by Saper RB1, Boah AR, Keosaian J, Cerrada C, Weinberg J, Sherman KJ.(PubMed)

Alternative Therapy: Yoga in Enhanced Immune Function

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

 Yoga practicing may have a profound effect in improved immune function against foreign invasion, particularly in age-related immune suppression in elderly individuals

Immune function is a natural reaction of immune system in protected our body against from foreign substances, cells, and tissues through proper expression of immune response.

Yoga, the ancient technique practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to evaluate the effect of yoga on mucosal immune function and mental stress with saliva samples collected from 23 adult women (age: 60.4 ± 10.4 years) before and after 90 minutes of yoga stretching or rest, researchers found that
1. Yoga group expressed a significant higher immunoglobulin A (SIgA)(a subclass of Immunoglobulin A (IgA) plays an important role in the immune function of mucous membranes)
concentration and secretion rate after yoga than before and in compared to control
2. The levels of cortisol( higher levels cortisol caused by stress has a negative effect in immune system) concentration and secretion rate were lower and testosterone(which plays an important role in immune function in reduced risk of autoimmune disease) secretion rate higher after yoga.
After further analysis and taking into account of other co founders, researcher said, " Yoga stretching can reduce stress and enhance mucosal immune function in elderly women."

Mucosal immune function is a first line of defense of immune system against antigens and infection and in regulated immune over reaction from unharmful sources.

According to general belief, yoga twist, compress and standing posts exercise play an important role in ameliorated alterations in the number of immune cells and cytokine dysregulation through lowering stress hormones production.

Additionally, the exercises also found to improve energy and energy balancing in the body which are necessary for immune system to function properly.

In the concerns of yoga expression in enhanced immune system through numbers of mechanism, researchers at the Daejeon University conducted a study in healthy adults, to highlight the beneficial effects of yoga practice on bio-parameters related to immune expression found that
1. Yoga group expressed a significantly reduced levels of relative oxygen species(ROS), including include peroxides, superoxide, hydroxyl radical, and singlet oxygen through regulating cellular metabolism in production of ROS which have been found to have a direct influence in T cells activation, apoptosis, and immune hypo responsiveness.2. Yoga group demonstrated  a improvement of immunity in increased levels of antioxidant in compared to control, through the effects of free radical scavengers in reduced cellular damage caused by over expression of ROS in inducing inflammation.
3. Yoga practice also significantly increased immune-related cytokines, such as interleukin-12, and interferon-γ,....which play an important role in reduced risk of inflammatory and auto immune diseases, including diabetes, atherosclerosis, rheumatic arthritis, and cancer.
4. The levels of plasma levels of adrenalin was reduced  and serotonin was increased in yoga group in compared with the control group.

Elevation of plasma levels of adrenalin caused by stress may suppress the immune system and increased levels of serotonin showed a opposite effect in increased killing ability of natural killer (NK) cells.
After taking into account of other co founders, Dr. Lim SA, the led researcher said, "Regular yoga practice remarkably attenuated oxidative stress (caused by imbalance of between the production of free radicals and antioxidants) and improved antioxidant levels of the body. Moreover, yoga beneficially affected stress hormone releases as well as partially improved immune function."
More importantly, in the review on the effects of yoga poses on psychological conditions including anxiety and depression, on pain syndromes, cardiovascular, autoimmune and immune conditions and on pregnancy., Dr. Field T, at the University of Miami School of Medicine, opinionated that yoga intervention induced the less production of cortisol, the hormone has a negative effect on immune system due to stress may indeed have a profound effect in enhanced immune cellular function, particularly in psychological conditions in regulating the autoimmune and immune conditions.

Taking altogether, There is no doubt that yoga practice may have a therapeutic effect in improved immune function against from foreign substances, cells, and tissues through numbers of mechanism involving different pathways.

Sources
(1) Yoga stretching for improving salivary immune function and mental stress in middle-aged and older adults by Eda N1, Ito H2, Shimizu K3, Suzuki S4, Lee E4, Akama T1.(PubMed)
(2) Regular Yoga Practice Improves Antioxidant Status, Immune Function, and Stress Hormone Releases in Young Healthy People: A Randomized, Double-Blind, Controlled Pilot Study by Lim SA1, Cheong KJ1.(PubMed)
(3) Yoga clinical research review by Field T1.(PubMed)

Friday, 17 November 2017

Alternative Therapy: Yoga Posture Practice for a Healthy Pregnancy and Outcome

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)


Yoga posture exercise may have a potential effect for a healthy pregnancy and outcome, some renowned studies suggested.

Posture is a state of holding the body still in a specific position, such as standing and sitting.

Yoga, the ancient practical technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the concerns of the adverse effect of yoga posture in pregnant women, researchers at the Jersey Shore University Medical Center filed the study of 25 healthy pregnant women with 10 assigned to regular yoga practice, 8 to familiar with yoga, and 7 with no yoga experience, matching age, race, body mass index, gestational age, and parity in each group, researchers found that
1. There was no change in maternal heart rate, temperature, pulse oximetry(the proportion of oxygenated hemoglobin in the blood in pulsating vessel), or fetal heart rate
2. The fetal heart rate across all 26 postures was normal.
3. There were no falls or injuries during the total cumulative 650 poses

Furthermore, after taking into account of other con founders researchers insisted that yoga posture also do not express a decreased fetal movement, contractions, leakage of fluid, or vaginal bleeding in the 24-hour follow-up.

Yoga postures have been found to ease back pain, indigestion, stress, and other pregnancy-related issues and to help you get smoothly through the next nine months.

However, some researchers suggested that some yoga postures must be avoid during pregnancy for the safety of mother and baby, such as inversions and prone postures which may have a potential in twisting your torso and close in on your belly, pressuring the belly,..... 

Pregnant women should discuss with their doctors before taking any class of yoga.

In support of yoga posture efficacy in reduced certain complications during pregnancy, Dr. Martins RF the lead author and colleagues at the UNICAMP School of Medicine, conducted a randomized controlled trial with 60 pregnant women (age range, 14-40 years) with report of lumbopelvic pain at 12 to 32 weeks of gestation from June 2009 to June 2011 assigned to the yoga group, practicing exercises guided by this method, and the postural orientation group, performing standardized posture orientation according to instructions provided in a pamphlet,  suggested that
1. Yoga group expressed a significant improvement of median pain score in compared to postural orientation group.
2. Both groups showed a decreased response in relation to posterior pelvic pain provocation tests and a gradual reduction in pain intensity during 10 yoga sessions.

After taking into account of other co-founders, researchers postulated  that although yoga group displayed a  a high score in reduced pain as indicated by the pain provocation tests, standardized posture orientation may also be considered as another form of exercise in improved pregnancy outcome.

In deed, according to Bec Conant, prenatal yoga instructor at Om Births and birth doula in Boston, (Yoga helps) women to develop strength, flexibility and confidence throughout their pregnancy and post-partum.

More interestingly, in the study of 335 women of 18 and 20 weeks of pregnancy attending the antenatal clinic at Gunasheela Surgical and Maternity Hospital in Bangalore, India, assigned to either (n=169)yoga postures and breathing, and meditation group and (n=166) or  control group, researchers found that yoga postures and breathing, and meditation group showed a higher birth weight and gestational age at delivery as well as lowering pregnancy complications such as isolated intrauterine growth retardation (IUGR) (p < 0.003) and pregnancy-induced hypertension (PIH) with associated IUGR (p < 0.025) in compared to control.

More importantly,there were no report of significant adverse effects noted in the yoga group.


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Yoga in Pregnancy: An Examination of Maternal and Fetal Responses to 26 Yoga Postures by Polis RL1, Gussman D, Kuo YH.(PubMed)
(2) Treatment of pregnancy-related lumbar and pelvic girdle pain by the yoga method: a randomized controlled study by Martins RF1, Pinto e Silva JL.(PubMed)
(2) Efficacy of yoga on pregnancy outcome by Narendran S1, Nagarathna R, Narendran V, Gunasheela S, Nagendra HR.(PubMed)

Alternative Therapy: Yoga Induced Calmness Under Great Pressure

Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)


Yoga may be one of best practice to induce calmness for people who are at the state of constant pressure, some studies suggested

Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study of 13 normal healthy adults to determine the effects of alternate nostril yoga breathing on (a) cerebral hemisphere asymmetry, and (b) changes in the standard EEG bands by assigned the participants into three sessions (a) alternate nostril yoga breathing (ANYB), (b) breath awareness and (c) quiet sitting, on separate days, researchers showed that alternate nostril yoga breathing (ANYB) expressed a higher result in induced calmness through stress and anxiety reduction.

Yoga alternate nostril breathing exercise demonstrated a significant effect to individuals calmness under certain pressure, probably is a result in the settle the mind and body, and emotions and decreased expression of an overactive or worrying mind.

Interestingly, certain posts in the sequence culminating in Padmasana(Lotus Pose) have found to achieve a calm mind stage, according to yoga journal.

Other researchers suggested that yoga inner demonstration of calmness may also have an profound effect in healing process of the whole person--mind, body, and spirit. 

Dr. Ott MJ at the Dana Farber Cancer Institute, said, "Formal and informal daily practice fosters development of a profound inner calmness and nonreactivity of the mind, allowing individuals to face, and even embrace, all aspects of daily life, regardless of circumstances".

In deed, yoga found the inner peace of participants through intimacy and ability to listen to the body even in sadness, grief and other festering emotions.

More importantly, in a study of 8 healthy male volunteers of the age group 25.9 +/- 3 (SD) years assigned to Santhi Kriya practice daily for 50 minutes for 30 days with volunteer's body weight, blood pressure, oral temperature, pulse rate, respiration, ECG and EEG were recorded before and after the practice on the 1st day and subsequently on 10th, 20th and 30th day of their practice, researchers at the end of the experiment postulated that there were a gradual and significant decrease in the body weight and an increase in alpha activity of the brain (P less than 0.001) during the course of 30 days.

Further analysis also suggested that increase of alpha activity both in occipital and pre-frontal areas of both the hemispheres of the brain indicated an increase of calmness.

More importantly, Santhi Kriya practice expressed an increases oral temperature by 3 degrees F and decreases respiratory rate significantly on all practice days.

Santhi Kriya yoga, a mixture of combined yogic practices of breathing and relaxation.

According to Dr. Richard P. Brown, Patricia L. Gerbarg, Philip R. Muskin in the book of
How to Use Herbs, Nutrients, & Yoga in Mental Health, Santhi Kriya total cortical  alpha activity in the brain is associated to relaxation calmness and awareness and the practice may be considered as an adjunct therapy to induce a state of greater relaxation.

Taking altogether, there is no doubt that people engaged in yoga lessons regularly are less likely to make wrong decision under pressure because of the result of yoga in expression of greater calmness.

For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Hemisphere specific EEG related to alternate nostril yoga breathing by Telles S1, Gupta RK2, Yadav A2, Pathak S2, Balkrishna A2.(PubMed)
(2) Yoga breathing through a particular nostril is associated with contralateral event-related potential changes by Telles S1, Joshi M, Somvanshi P.(PubMed)
(3) Effect of Santhi Kriya on certain psychophysiological parameters: a preliminary study by Satyanarayana M1, Rajeswari KR, Rani NJ, Krishna CS, Rao PV.(PubMed)

Food Therapy: Beet or Dietary Nitrate-rich Beetroot Juice in Reduced Risk of Hyperlipidemia


Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

In compared to conventional and herbal medicine; food therapy  takes even longer (sometimes more than six months) to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Beet may hold a potential use as a functional food in reduced levels of fat and cholesterol in patient with hyperlipidemia

Hyperlipidemia is a medical condition characterized by high cholesterol and fat in the blood stream.

Beet, best known as the beetroot or garden beet and belongings to the amaranth family, is a perennial plant with leafy stems growing to 1–2 m tall.

According to the study of rats fed with high fat diet induced hypercholesterol showed a significant reduced levels of fat and cholesterol through expression of liver protective effects by examined rat lipid profile of total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol and triglycerides and histopathological analysis of liver, after treatment with beetroot.

Lipoproteins are basically fat and cholesterol, along with a lipid membrane containing proteins called apolipoproteins with function to transport lipid molecules in blood stream and extracellular fluid.in our body.

Lipoprotein(a) or Lp(a) calculated by low-density lipoprotein cholesterol (LDL-C) in the blood stream from measured levels of total cholesterol, triglycerides and high-density lipoprotein cholesterol (HDL-C) may be an important marker for the risk developing of heart disease.

Other, in the double-blinded, placebo-controlled study of  patients older than 40 years, subjects instructed to take either the NO dietary supplement called Neo40 Daily® or placebo twice daily on an empty stomach for 30 days, NO dietary supplement group showed a significant increase in both plasma nitrite (P < .01) and nitrate with elevated triglycerides reduced by 72% in compared placebo group.

Nitrite is a group of chemical compound containing the anion NO2− and Nitrate has a chemical symbol of NO31-
Nitrates are relatively harmless, if they are  not taken in high amounts.

The study also emphasized the achievement of nitrite reductase activity of nitrate-rich beetroot juice in improven NO status, involving decreased and modify cardiovascular risk factors, including high levels of triglycerides in the circulatory system.

Also, in a randomized controlled 5-week crossover intervention, separated by a 3-week washout involved subjects (n = 25) aged 58.6 (1.1) years (mean and SD) with a BMI of 26.6 (0.5) kg/m(2) and a total cholesterol (TC) of 5.8 (0.1) mmol/L (mean and SEM) given a high fiber (HF) and low fiber (LF) diet, treatment of high fiber (HF) group, expressed a Significant reduction in C-reactive protein (CRP) and a significant reduction in fibrinogen.

Fibrinogen, is an essential protein for blood clot formation.

Although the study found no influence of beet fiber in contribution to lower of blood cholesterol but ameliorated the inflammatory effect in induced cardiovascular disease of hypperlipidemic patients.

More importantly, nitrates and nitrites occur naturally in vegetables and also used as preservative added to in many foods including meat products. Injection of high amount in the body may induce anemic-like disorders and cancers.

Taking together, whole food and nitrate-rich beetroot juice may have a potential effect in reduced risk high blood cholesterol inducing heart disease through elevated levels of antioxidants and hepo- protection.

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You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

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Holistic System In Existence That Will Show You How To
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A Simple Cooking Technique That Cuts The Calories & Glycemic
Impact In Rice, Pasta, And Potatoes In Half

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Sources
(1) Beta vulgaris subspecies cicla var. flavescens (Swiss chard): flavonoids, hepatoprotective and hypolipidemic activities by Hashem AN, Soliman MS, Hamed MA, Swilam NF, Lindequist U, Nawwar MA.(PubMed)
(2) All-natural nitrite and nitrate containing dietary supplement promotes nitric oxide production and reduces triglycerides in humans by Zand J1, Lanza F, Garg HK, Bryan NS.(PubMed)