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Friday, 17 January 2014

Herbal Burdock and Anti- inflammatory effects


Burdock is plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro. It has been used over thousand of years in Chins and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.
Inflammation is a condition of Immune system self-protection to remove harmful stimuli, including damaged cells, irritants, pathogens... from our body.

The ingredientsIt contains carbonated water, sugar,, manloid colourings, phosphoric acid, citric acid and a good amount of dietary fiber, calcium, potassium, and amino acids and chemicals compounds of guaianolide, arctinone, arctinal, methyl arctate,11-tridecadien-3,5,7,9-tetraynde-hydrocostus lactone,dehydrodihydrocostus lactone, 3-octenoic acid, 3-hexenoic acid etc.

The benefits
Topic dermatitis is a chronic, allergic inflammatory skin disease. Butanol extract of A. lappa (ALBE) has showed to inhibit the expression of IL-4 and IL-5 by downregulating MAPKs and NF-κB activation in ConA-treated splenocytes and ALBE may have beneficial effects in the treatment of allergic diseases, including atopic dermatitis. In other study, the lactone sesquiterpene onopordopicrin enriched fraction (ONP fraction) from Arctium lappa  exerts its Anti-inflammatory intestinal activity in acute experimental colitis. Also the Arctigenin, a bioactive constituent from dried seeds of Arctium lappa L. (Compositae), showed a suppressed lipopolysaccharide (LPS)-stimulated NO production and pro-inflammatory cytokines secretion as well as  inhibited the expression of iNOS and iNOS enzymatic activity.



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Back to Herbal Therapy http://kylejnorton.blogspot.ca/p/herbal-therapies.html 


The Side effects
1. Overdose can be poisoning and may lead to symptoms of
acute poisoning include phenothiazines, tricyclic antidepressants, and antihistamines.
2. It may cause dermatitis and allergic/inflammatory responses to certain people with contact as a result of lactones which the plant produces.
3. Do not use burdock if you are pregnant or breast feeding.
4. Etc.

References
(1) Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L.
Sohn EH, Jang SA, Joo H, Park S, Kang SC, Lee CH, Kim SY.(PubMed)
(2) Anti-inflammatory intestinal activity of Arctium lappa L. (Asteraceae) in TNBS colitis model. by de Almeida AB, Sánchez-Hidalgo M, Martín AR, Luiz-Ferreira A, Trigo JR, Vilegas W, dos Santos LC, Souza-Brito AR, de la Lastra CA.(PubMed)
(3) In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway by Zhao F, Wang L, Liu K.(PubMed)