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Monday, 20 January 2014

Phytochemicals Phytic acid and Cancers

Phytic acid (Inositol hexaphosphate) are phytichemicasl of the organic acid found abundantly in nuts, sesame seeds, soybeans, wheat, pumpkin, beans, almonds, etc.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

The health benefits
Inositol hexaphosphate (IP6) or phytic acid has been observed in many studies in exerting an inhibition of tumor growth and induction of cell differentiation in the presence of IP6 in a few cancer cell lines including colon, nipple, breast, prostate, cervix, liver, pancreas, melanoma and glioblastoma, through its effects as an antioxidant and ability to enhance NK-cells, of influence on cell cycle, in induction of differentiation in transformed cells and  in activation of programmed death pathways. In otehr study, Inositol hexaphosphate (IP6) showed to inhibit cell growth, decrease cellular proliferation and cause differentiation of malignant cells often resulting in a reversion to normal phenotype. 

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Reference

(1) [Phytic acid--anticancer nutriceutic].[Article in Polish] by Nawrocka-MusiaƂ D, Latocha M.(PubMed)
(2) IP6: a novel anti-cancer agent by Shamsuddin AM, Vucenik I, Cole KE.(PubMed)