The liver is the largest internal organ that not only plays an essential role to cleanse the blood coming from the digestive system before passing them to other parts of the body but secrets cholesterol to aid digestive function, produce steroid hormones and vitamin D and build strong cell walls.
Steatosis is a condition caused by abnormal retention of lipids within a cell or organ. Hepatic steatosis is a medical condition caused by the accumulation of fat in the liver.
In other words, if the fat of your liver is more than 5% of liver weight, you are considered to have hepatic steatosis. Over time, untreated hepatic steatosis can lead to advanced forms of nonalcoholic fatty liver disease which have been found to induce negatively the function of the liver, particularly. in patients with obesity-associated with alcohol intoxication and/or hepatic disorders.
There are several mechanisms involved in the accumulation of intrahepatic fat, including increased flux of fatty acids to the liver, increased de novo lipogenesis, and/or reduced clearance through β-oxidation or very-low-density lipoprotein secretion.
People who are obese, having the condition of insulin resistance or diabetes, dyslipidemia, hypertension, metabolic syndrome, rapid weight loss, using hepatotoxic medications total parenteral nutrition (TPN) are at the increased risk of hepatic steatosis.
Conventionally, there is no effective treatment of liver steatosis. However, treatment of liver steatosis in obese are focusing to reduce weight and symptoms and improve quality of life, totally depending on the severity of the disease.
On finding a natural compound for the prevention of liver steatosis, researchers examined the alleviation effect of KBH-1, an herbal mixture of Saururus chinensis, Curcuma longa and Polygala tenuifolia in obesity-induced hepatic steatosis.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) KBH-1, an herbal composition, improves hepatic steatosis and leptin resistance in high-fat diet-induced obese rats by Lee JH1, Lee JJ1, Cho WK1, Yim NH1, Kim HK2, Yun B2, Ma JY. (PubMed)
(2) The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosisand inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells by Yoon S1, Kim J1, Lee H1, Lee H1, Lim J1, Yang H2, Shin SS3, Yoon M. (PubMed)