Friday, 30 August 2019

Lycopene Protects the Heart Failure Against the Risk of Cardio Events

By Kyle J. Norton

The heart is a four-chambered, hollow muscle and double acting pump located in the chest between the lungs is a muscular organ in the human body.

The heart formed an important part of the circulatory system that pumps blood through the blood vessels to nourish the body and assist in the removal of metabolic wastes.

According to the statistic provided by the American Heart Foundation, on average, an American dies of CVD every 38 seconds. Cardiovascular disease (CVD) accounted for 840,678 deaths in the US in 2016 and the condition also claim more lives each year than all forms of cancer and chronic lower respiratory disease combined

In 2016, cardiovascular diseases cause the death of 2,303 deaths each day, in the US.

Heart failure (HF) is a medical condition associated with the reduced function of the heart muscle that can not maintain blood flow to meet the body's needs, leading to symptoms of 
* Shortness of breath and excessive tiredness are caused by the congestion in your lungs in the process of inhaling oxygen and exhaling carbon dioxide.
* Leg swelling is a condition caused by fluid to back up in your lungs and in other parts of your body such as your ankles.

Believe it or not, approximately 600, 000 Canadian are living with heart failure or 16% of the entire population.

Conventionally, there is no cure of heart failure, most common treatment is focusing on lifestyle changes and managing the condition with an aim to improve quality of life.
Lycopene is a phytochemical in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

On finding a potential compound for the prevention of heart failure HF, researchers examined the dietary intervention in patients with HF on lycopene on biomarkers of inflammation.

A total of 40 patients with HF were randomly assigned to 1 of 2 groups: lycopene intervention and usual care that received 29.4 mg of lycopene intake per day by drinking an 11.5 oz serving of V8 100% vegetable juice for 30 days.

According to the tested analysis, plasma lycopene levels increased in the intervention group compared with the usual care group.

Furthermore, C-reactive protein levels associated with the sign of inflammation and a potential risk factor for heart disease decreased significantly in the intervention group in women of 5.9 ± 3.7 mg/dL and but not in men 2.2 ± 2.1 mg/dL compared to postintervention of 4.5 ± 3.6 mg/dL and 2.4 ± 2.1 mg/dL, respectively.

In other words, lycopene significant reduce the risk of cardiovascular disease of heart failure patients by decreasing the levels of CRP in women.

Moreover, according to the results of a prospective study of 212 patients with HF intervented by dietary intake of lycopene and sodium of 4-day food diaries, higher lycopene intake was associated with longer cardiac event-free survival compared with lower lycopene intake.

More precisely, increased lycopene intake has the potential to improve cardiac event-free survival in patients with HF.

Taken altogether, lycopene found in tomato may be considered supplements for the improvement of cardio events, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Lycopene dietary intervention: a pilot study in patients with heart failure by Biddle MJ1, Lennie TA, Bricker GV, Kopec RE, Schwartz SJ, Moser DK. (PubMed)
(2) Higher dietary lycopene intake is associated with longer cardiac event-free survival in patients with heart failure by Biddle M1, Moser D, Song EK, Heo S, Payne-Emerson H, Dunbar SB, Pressler S, Lennie T. (PubMed)

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