Collard Greens Inhibits the Fat Accumulation in Obese Patients

By Kyle J. Norton

Obesity is a chronic condition characterized by excess body fat has accumulated over time. People with a BMI of over 30 is considered obese.

Similarly, overweight is a condition of excess body weight relative to height. People with a BMI ranged from 25 to 29.9 is considered overweight.

According to the statistics, 68% of the American population is either overweight or obese. Obesity has been found to induce adverse effects nearly every system of the human body, leading to increased risk of numerous diseases, including diabetes and cardiovascular disease.

Furthermore, the rate of obesity in the US and Canada continues to climb at an alarming rate, leading to significant burdens to the country economy and health care system.

Epidemiologically, most common symptoms of obesity are breathlessness, increased sweating, inability to cope with physical activity, feeling very tired every day, back and joint pains, low confidence, and self-esteem and feeling isolation

According to the CDC,  most common complications associated with obesity are coronary heart disease, stroke, type 2 diabetes, cancer of breast, colon, endometrial, gallbladder, kidney, and liver and sleep apnea.

Currently, there is no effective treatment of the disease. However, some researchers suggested that combat the powerful environmental factors that influence eating and physical activity may be the best approach to reduce the risk of obesity.

Bariatric surgery is used as an option for management that causes a reduction in the amount of food you are or a reduction in the absorption of calories from the food you eat, or both.

The surgery has been proposed to patients with extreme obesity (BMI of 40 or higher) due to weight-induced a serious weight-related health problem, such as diabetes or high blood pressure. 

Furthermore, this type of surgery has posted a serious risk of many patients if the commitment of making lifelong changes in the eating and exercise habits cannot be followed through.

Collard Green is a species of Brassica Oleracea, belongings to the family Brassicaceae with unknown origin. Today, the plant is cultivated commercially for its thick, slightly bitter edible leaves.

With an aim to find a natural food for the prevention and treatment of obesity, researchers examined the effect of sulforaphane found abundantly in collard greens.

In a high-fat diet (HFD)-induced obesity in C57BL/6N mice which were fed a normal diet (ND), HFD or HFD plus 0.1% sulforaphane (SFN) for 6 weeks, researchers found that SFN administration not only attenuated HFD-induced visceral adiposity that stored around a number of important internal organs such as the liver, pancreas and intestines, adipocyte hypertrophy associated with an enlargement of adipose tissue but also ameliorated fat accumulation in the liver.

Furthermore, SFN decreased the elevated levels of serum total cholesterol and leptin, and liver triglyceride in HFD-SFN-fed mice compared to HFD-fed mice.

SFN also inhibited the expression of a gene associated with the promotion of inflammation in the adipose tissue of HFD-SFN mice and increased the adiponectin function in regulating glucose levels and fatty acid breakdown.

Moreover, reductase expression associated with the production of cholesterol was decreased and an antibody associated with fatty acid utilization was increased in lycopene treat group compared with HFD-fed mice.

Taken altogether, collard green processed abundantly SFN may be considered supplements for the prevention and treatment of obesity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of SFN in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Potential effects of sulforaphane to fight obesity by Martins T1, Colaço B1,2, Venâncio C1,2, Pires MJ1,3, Oliveira PA1,3, Rosa E1, Antunes LM. (PubMed)
(2) Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice by Kyeong-Mi Choi, Youn-Sun Lee, Wonkyun Kima, Seung Jung Kimb, Kyong-Oh Shina, Ji-YeonYuc, Mi Kyeong Lee, Yong-Moon Lee, Jin Tae Honga, Yeo-PyoYuna, Hwan-SooYooa. (Science Direct)