The colon formed part of the digestive system is also called the large intestine which plays a critical role in removing water, salt, and forming a stool through its muscles lines.
There are over 100 trillion live in the colon that maintains a healthy balance with the body.
In a normal or healthy individual, gut microbiota besides protecting the host against pathogens that cause infectious disease, it also has strong imparts in some specific function in the host, including
* Nutrient metabolism is a process that absorbs end products of food digestion such as monosaccharides, glucose from carbohydrates, monoacylglycerol and long-chain fatty acids from lipids, and small peptides and amino acids from protein.
* Xenobiotic metabolism is the action that protects the host against chemicals that affect normal metabolism.
* Drug metabolism is the process to alter chemical of a drug that may cause harm to the body
* Gut microbiota also has been found to protect gut mucosal barrier in preserving the ability to absorb nutrients.
* Gut microbiota immunomodulatory activity reduced risk of disease associated with chronic inflammation of the digestive tract, such as bowel inflammatory disease.
However, there are several factors that may have strong impacts on gut microbiota. Dr. Sai Manasa Jandhyala, the lead scientist wrote, " (1) the mode of delivery (vaginal or cesarean); (2) diet during infancy (breast milk or formula feeds) and adulthood (vegan based or meat based); and (3) use of antibiotics or antibiotic like molecules that are derived from the environment or the gut commensal community.
And "A major concern of antibiotic use is the long-term alteration of the normal healthy gut microbiota and horizontal transfer of resistance genes that could result in the reservoir of organisms with a multidrug-resistant gene pool".
On finding a natural compound for the improvement of colon health, researchers examined the effect of cooked navy bean (NB) or black bean (BB) flours on the colonic microenvironment in the gut.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Navy Beans Impact the Stool Metabolome and Metabolic Pathways for Colon Health in Cancer Survivors by Baxter BA1, Oppel RC2, Ryan EP. (PubMed)
(2) White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate by Monk JM1, Zhang CP1, Wu W2, Zarepoor L1, Lu JT1, Liu R2, Pauls KP3, Wood GA4, Tsao R2, Robinson LE5, Power KA. (PubMed)
(3) Role of the normal gut microbiota by Sai Manasa Jandhyala, Rupjyoti Talukdar, Chivkula Subramanyam, Harish Vuyyuru, Mitnala Sasikala, and D Nageshwar Reddy. (PMC)