Thursday, 1 August 2019

Cranberry Inhibits the Risk and Symptoms of Bladder Cystitis

By Kyle J. Norton

The bladder formed part of the secretary system is a muscular sac in the pelvis, just above and behind the pubic bone, playing a critical role for collect and secret urine made by the kidneys.

Cystitis is a medical condition associated with inflammation of the bladder, leading to the symptoms of bladder irritation and swelling. Women are prone to the condition compared to men.

Bladder cystitis or bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic syndrome associated with pelvic pain urgency and frequency. The condition is not considered a disease due to the difficulty to rule out all differential diagnosis only from history.

Most common cause of the bladder cystitis is bacterial infection involved in the urinary tract. However, radiotherapy, long-term use of certain medicines and hygiene products have also been found to induce bladder inflammation.

Most common symptoms of cystitis are frequent urge to urinate, urge to urinate after you’ve emptied your bladder, cloudy or strong-smelling urine, pain during sexual intercourse and sensations of pressure or bladder fullness.

In serious cases, patients may also experience symptoms of fever, blood in your urine and cramping in your abdomen or back.

Conventionally, antibiotics are the first line of treatment for bladder cystitis, if the bacteria that cause the infection has been identified.

Most cases of acute cystitis are treated by nitrofurantoin monohydrate/macrocrystals, trimethoprim-sulfamethoxazole (TMP-SMX) accompanied by nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil) or acetaminophen (Tylenol) to reduce pain and inflammation.

Cranberry is an evergreen dwarf shrub, genus Vaccinium, belongings to the family Ericaceae, native to Northern America and Southern Asia. Because of its health benefits, cranberry has been cultivated in some parts of the world for commercial profit and used in traditional and herbal medicine to treat wounds, urinary disorders, diarrhea, diabetes, stomach ailments, and liver problems.

On finding a potential compound for the treatment of prostate diseases, researchers examined the effect of highly standardized cranberry capsules (containing 72 mg proanthocyanidins [PACS]) compared with that of placebo capsules on the incidence and severity of radiation cystitis.

In a total of 41 men with prostate cancer participated in a double-blinded randomized placebo-controlled study, taking one capsule a day at breakfast during treatment and for 2 weeks after treatment completion, researchers, according to the tested analysis found that

Cranberry capsules show a significantly reduced incidence of cystitis to 65% compared to placebo capsules of 90%.

The severe cystitis is only present in 30% of men in the cranberry arm and 45% of the placebo.

Overall, the incidence of pain/burning is significantly lower in the cranberry compared to placebo.

Additionally, cranberry injection shows less pain/burning, stronger urine stream and used significantly fewer pads/liners, in men on the low hydration regimen comapred to those on the high hydration regimen.

Based on the findings, researchers concluded. "Men receiving radiation therapy for prostate cancer may benefit from using cranberry capsules, particularly those on low hydration regimens or with baseline urinary symptoms".

Taken altogether, cranberry may be considered a remedy for the prevention and treatment of prostate cancer patients, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Standardized cranberry capsules for radiation cystitis in prostate cancer patients in New Zealand: a randomized double blinded, placebo controlled pilot study by Hamilton K1, Bennett NC, Purdie G, Herst PM. (PubMed)
(2) Cranberry and recurrent cystitis: more than marketing? by Micali S1, Isgro G, Bianchi G, Miceli N, Calapai G, Navarra M. (PubMed)

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