Tuesday, 27 August 2019

Herbal Turmeric Promotes Skin Regeneration

By Kyle J. Norton

Skin is a large organ that protects our internal organs and tissues by shielding them from the invasion of foreign pathogens. A number of different components, such as water, protein, lipids, and different minerals and chemicals has been found to make up the skin integrity.

Furthermore, the skin accompanied by the liver and kidney forms a detoxed triad by eliminating toxins from the body.

Skin regeneration or repair is a natural process that epithelial cells restore the epidermis once the dermis has been regenerated. 

However, in major injuries, the repair mechanisms may not completely restore the skin to its original condition, leading to the formation of scars.

In details, the skin regenerates through 3 stages
* Initial phase or acute phase of infection. 
The immune system white blood cells of the first line of defense stimulate the blood platelets to cover the wound or injury and production of proinflammatory cytokines, leading to the creation of new blood vessels to replace those that were damaged in the precipitating incident.

* Regeneration of the epidermis and dermis involved in the proliferation of the cells of the stratum basale and the move of a healthy portion of the dermis at the edges of the wound into its interior.

Any disruption of the process of skin regeneration can lead to the formation of scars

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a potential compound for the treatment of skin wound, researchers examined the effect of curcumin the main constituent found in turmeric on free radical scavenging and anti-inflammation activity.

During the experiment, curcumin was found to modulate the phase II detoxification enzymes associated with detoxification reactions and the protection against oxidative stress.

Furthermore, injection of curcumin also enhanced skin regeneration and wound healing.

Moreover, curcumin protects skin by quenching free radicals and reducing inflammation involved in protein that stimulates the production of inflammatory cytokines.

Curcumin administration also promoted skin regeneration in wound healing by improving wound-healing time, collagen deposition and increased fibroblast and vascular density in wounds.

Additonally, the effects of skin regeneration and wound healing was also attributed to the compound's proangiogenic property.

Based on the findings, researchers said, "These studies suggest the beneficial effects of curcumin and the potential of this compound to be developed as a potent nontoxic agent for treating skin diseases".


Taken altogether, turmeric processed a high amount of curcumin may be considered supplements for the enhancement of skin regeneration in wound healing, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Skin regenerative potentials of curcumin by Thangapazham RL1, Sharad S, Maheshwari RK. (PubMed)
(2) Beneficial role of curcumin in skin diseases by Thangapazham RL1, Sharma A, Maheshwari RK. (PubMed)

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