Monday, 5 August 2019

Lycopene Prevents the Onset of Metabolic Syndrome

By Kyle J. Norton

A metabolic syndrome is a group of conditions associated with an increased risk of cardiovascular disease and types 2 diabetes, including high blood pressure, sugar, cholesterol and triglyceride levels and excess body fat around the waist.

Epidemiological studies suggested if you have 3 of the above syndrome you have metabolic syndrome.

According to statistics, metabolic syndrome is a growing prevalence in the Western world, In the US, 30% of Americans are living with metabolic syndrome,

In other words, 1 in 5 people in Canada has metabolic syndrome, affecting 19.1% of all Canadian adults.

The CDC statistic suggested, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 25.3% to 34.2% according to the data from 1988–1994 to 2007–2012.

Most common metabolic syndrome are age, family history of metabolic syndrome, physical activity, and women diagnosed with polycystic ovary syndrome.

Common complications of untreated metabolic syndrome epidemiologically have been found by experts to complicate chronic illness such as atherosclerosis, nonalcoholic fatty liver disease, and kidney diseases.

Symptoms of signs of metabolic syndrome depending types of affected conditions and complications.

Some researchers suggested that in the US, metabolic syndrome may be correlated with the promotion of a high-fat diet over the past few decades.

Dr. Silvia Moreno-Fernández wrote, "The widespread of MetS in actual society, mainly in developed countries, is becoming an important health problem and is increasing the need to develop new treatments against this pathology is increasing fast".

And, "High-fat/high-glucose fed rats showed an increased bodyweight, abdominal circumference, and fat deposition, combined with oxidative stress, impaired glucose tolerance, dyslipidemia, and mechanical allodynia. Altogether, our results showed an early-stage MetS which, in addition, could lead to T2DM and cardiovascular disease development over time in HFG animals. ".

The results strongly suggested that both metabolic syndrome and obesity in the US population are attributed to the Western diet pattern.

In other words, by changing to a healthy diet such as traditional diet, the risk of obesity and metabolic syndrome can be decreased substantially.

Lycopene is a phytochemical found in tomato in the class of carotenoid, a natural pigment with no vitamin A activity found abundantly in tomatoes and other red fruits and vegetables, such as red carrots, watermelons, and papayas,

Tomatoes provide about 80% of the lycopene in the world diet. In plants, lycopene protects the host against excessive photodamage and perform various functions in photosynthesis.

With an aim to find a potent compound for reducing risk cardiovascular disease and diabetes, researchers examined the effects of lycopene on metabolic syndrome.

In a total of 13 196 participants, aged 20 years and older, divided into three groups according to serum concentrations of lycopene, researchers found that prevalence of the metabolic syndrome associated with levels of antioxidant was significantly higher in the normal and overweight group compared to the obese group.

In other words, the risk of metabolic syndrome depending on the levels of lycopene in the body only affects people with normal weight or overweight.

Additionally, the study included A total of 2499 participants 20 years and older with metabolic syndrome that were divided into 3 groups based on their serum concentration of lycopene suggested that levels of lycopene also showed significant effects on HRs of mortality.

In other words, people with higher levels, compared to those of lower serum lycopene concentration.have a lower mortality rate and hazard ratios (HR).

Taken altogether, lycopene found in tomato may have a strong effect on the initiation of metabolic syndrome, particularly in normal weight and overweight individuals, pending on the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Higher levels of serum lycopene are associated with reduced mortality in individuals with metabolic syndrome by Han GM1, Meza JL2, Soliman GA3, Islam KM1, Watanabe-Galloway S. (PubMed)
(2) The influence of BMI on the association between serum lycopene and the metabolic syndrome by Han GM1, Soliman GA2, Meza JL3, Islam KM1, Watanabe-Galloway S. (PubMed)
(3) High Fat/High Glucose Diet Induces Metabolic Syndrome in an Experimental Rat Model by Silvia Moreno-Fernández,1,2 Marta Garcés-Rimón,3 Gema Vera,2,4 Julien Astier,5Jean François Landrier,5 and Marta Miguel. (PMC)

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