Risk of preterm labor is found to associated to coffee caffeine intake during pregnancy, renowned studies of Institutes suggested.
Coffee, popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
According to the Istituto di Ricerche Farmacologiche Mario Negri, in a case-control study conducted at University clinics of North Italy of 502 women delivered at <37 weeks of gestation and 1966 women gave birth at term (>or=37 weeks of gestation) to healthy infants acted as control, coffee caffeine consumption in the third trimester of pregnancy showed a inversely related in SGA cases compared to NGA.
In compared to non coffee drinkers, low drinkers expressed a similarity of relative risk of overall intake of caffeine closed near the unity for both SGA and NGA preterm birth.
Dr. Chiaffarino F, the lead author said, " a low consumption of coffee during pregnancy may not have significant effects on preterm birth."
Interesting, Caffeine intake during third-trimester caffeine consumption showed a non significantly inverse association with preterm delivery.
Additionally, the review of literature of data base by the Howard University,suggest that the risk of women who consumed over 300mg of caffeine a day is only associated with small reductions in infant birth weight. leading to premature or low-birth-weight infants.
Dr, Hinds TS, the lead author said, "caffeine is not a human teratogen, and that caffeine appears to have no effect on preterm labor and delivery".
Taking altogether, conflict evidences suggested that additional large and mutli centre studies are necessary in clarified these contradictions.
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(1) Coffee drinking and risk of preterm birth by Chiaffarino F1, Parazzini F, Chatenoud L, Ricci E, Tozzi L, Chiantera V, Maffioletti C, Fedele L.(PubMed)
(2) Case-control study of caffeinated beverages and preterm delivery by Pastore LM1, Savitz DA.(PubMed)
(3) The effect of caffeine on pregnancy outcome variables by Hinds TS1, West WL, Knight EM, Harland BF.(PubMed)