Friday, 3 November 2017

Food Therapy: Coffee Intake < 3 Cups/day In Reduced Risk of Gastric Cancer

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Good news to coffee lovers, coffee and coffee caffeine consumption daily and regularly might have a potential in reduced risk of gastric cancer, the recent study suggested.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the joint study led by the the Children's Hospital of Chongqing Medical University, by searching of the data base of published literature, including 22 studies (9 cohort and 13 case-control studies) involving 7,631 cases and 1,019,693 controls, the relative risk of gastric cancer and coffee intake was shown in following
1. Relative rsik of gastric cancer was 0.94 (95% CI: 0.80-1.10) for the highest category of coffee consumption compared with the lowest category
2. In compared to non drinker, the relative risk is and 0.93 
3. The relative risk of <1 cup/day, 1-2 cups/day and 3-4 cups/day coffee consumption compared with nondrinkers were 0.95, 0.92 and 0.88, respectively,

The information findings, after considering other factors, demonstrated a significant association between coffee intake and decreased gastric cancer risk in case-control studies.

Contraditively, in the study of long term effect of coffee consumption and risk of gastric cancer in US, through searching PubMed and Embase from January 1996 through February 10, 2015 of a total of 2019 gastric cancer incident cases among 1,289,314 participants with mean follow-up periods ranging from 8 to 18 years, suggested that
1. The relative risk (RR) of every 3 cups/day increment of total coffee consumption was 1.07
2. the relative risk of 1.18 in compared with the lowest and the highest categories of coffee consumption
3. RR of 1.06 in compared the second highest and Lowest category (median 3.5 cups/day),
4 RR of 0.97 (95% CI = 0.79-1.20) for the third highest and lowest category (median 1.5 cups/day).

Dr., the lead author said, "Current evidence indicated there was no nonlinear association between coffee consumption and gastric cancer risk. However, high coffee consumption (more than 6.5 cups/day) might increase the risk of gastric cancer in the US population".

Other, subgroups analysis suggested that coffee intake do not have potential effect in gastric risk, but in US subgroup, risk of gastric significant increased risk with the relative ratio of 1.36 in the studies with <10 years of follow-up, particular in those studies without adjustment for smoking.

Taking altogether, although there is conflict evidences, coffee consumption < 3 cups/day was shown to ameliorated risk of gastric cancer.

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(1) Coffee consumption and risk of gastric cancer: an updated meta-analysis by Xie Y1, Huang S1, He T2, Su Y3.(PubMed)
(2) Long-Term Coffee Consumption and Risk of Gastric Cancer: A PRISMA-Compliant Dose-Response Meta-Analysis of Prospective Cohort Studies by Zeng SB1, Weng H, Zhou M, Duan XL, Shen XF, Zeng XT.(PubMed)

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