Tuesday, 7 November 2017

Food Therapy: Coffee and Coffee Caffeine Intake in Risk to Childhood Brain Tumors?

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Expected mothers consuming high amount of coffee and coffee caffeine during pregnancy may or may not associate to increased risk of offspring childhood brain tumors, respectable studies suggested.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

According to the Australian case-control study conducted between 2005 and 2010 with children  recruited from 10 pediatric oncology centers and control children by nationwide random-digit auto account dialing, after taking taking into account of confounders
1. There are little evidence linking gestational consumption of any coffee and CBT risk.
2. The odd ration of risk childhood brain tumors was 1.76 among children aged under 5 years, for any coffee consumption during pregnancy.
3. For women drinking ≥2 cups per day during pregnancy, the relative ratio was 2.52.

Other, in the evaluated pooled data from two French national population-based case-control studies with similar designs conducted in 2003-2004 and 2010-2011 in mothers of 510 CBT cases (directly recruited from the national childhood cancer register) and 3,102 controls aged under 15 years, researchers also suggested that there is no evidence of coffee and coffee caffeine consumption in risk of childhood brain tumors.

Additionally, in the investigation of epidemiological Study on childhood Cancer and Leukemia ESCALE study and a national population-based case-control study carried out in France in 2003-2004. researchers found that there is profound risk between ependymomas, a tissue of the central nervous system and the highest consumption of coffee.

Dr. Plichart M, the lead author said, "maternal coffee and tea consumption during pregnancy may also increase the risk of CNS tumours".

Taking together, there are contradictory evidences to associate risk of childhood brain tumors to high amount intake of coffee and coffee caffeine during pregnancy. But women having a history of previous incidence should reduce intake of coffee as a preventive risk factor.

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(1) Maternal consumption of coffee and tea during pregnancy and risk of childhood brain tumors: results from an Australian case-control study by Greenop KR1, Miller M, Attia J, Ashton LJ, Cohn R, Armstrong BK, Milne E.(PubMed)
(2) Parental smoking, maternal alcohol, coffee and tea consumption and the risk of childhood brain tumours: the ESTELLE and ESCALE studies (SFCE, France) by Bailey HD1, Lacour B2,3, Guerrini-Rousseau L4, Bertozzi AI5, Leblond P6, Faure-Conter C7, Pellier I8, Freycon C9, Doz F10, Puget S11, Ducassou S12, Orsi L2, Clavel J2,3.(PubMed)

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