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Coffee intake regularly may decrease risk of esophageal cancer developing, according to the study conducted by the Istituto di Ricerche Farmacologiche "Mario Negr".
Esophageal cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the esophagus, the food tube that runs between the throat and stomach.
According to the data base extracted from hospital-based case-control studies conducted in Italy and Switzerland on oral/pharyngeal cancer included 749 cases and 1772 controls, with esophageal cancer 395 cases and 1066 controls, researchers indicated that the relative ratio of esophageal cancer for patients drinking >3 cups/day were 0.6. And the inverse association was more profound if taking other factors into account.
The study also insisted, there are no association between risk of esophageal cancer and decaffeinate coffee drinking and people consuming coffee in low amounts.
Additionally, in the study of 38,679 subjects aged 40-64 years with no previous history of cancer, 157 cases of oral, pharyngeal, and esophageal cancers identified during 13.6 years of follow-up, coffee intake regularly of 1 cup or more showed a inverse association in risk of esophageal cancer, regardless to sex and cancer site.
1. During a mean follow-up of 11.1 years, coffee intake regular patients showed a significant lower risk of esophageal cancer in compared to non drinkers group.
2. Men coffee consumption was inversely related to esophagealsquamous cell carcinoma (ESCC), but not among women.
3. Risk of esophageal cancer was reduced in current smokers with coffee consumption.
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(1) Coffee and tea intake and risk of oral, pharyngeal and esophageal cancer by Tavani A1, Bertuzzi M, Talamini R, Gallus S, Parpinel M, Franceschi S, Levi F, La Vecchia C.(PubMed)
(2) Coffee consumption and the risk of oral, pharyngeal, and esophageal cancers in Japan: the Miyagi Cohort Study by Naganuma T1, Kuriyama S, Kakizaki M, Sone T, Nakaya N, Ohmori-Matsuda K, Nishino Y, Fukao A, Tsuji I.(PubMed)
(3) Tea and coffee consumption and risk of esophageal cancer: the European prospective investigation into cancer and nutrition study by Zamora-Ros R1, Luján-Barroso L, Bueno-de-Mesquita HB, Dik VK, Boeing H, Steffen A, Tjønneland A, Olsen A, Bech BH, Overvad K, Boutron-Ruault MC, Racine A, Fagherazzi G, Kuhn T, Katzke V, Trichopoulou A, Lagiou P, Trichopoulos D, Tumino R, Panico S, Vineis P, Grioni S, Palli D, Weiderpass E, Skeie G, Huerta JM, Sánchez MJ, Argüelles M, Amiano P, Ardanaz E, Nilsson L, Wallner B, Lindkvist B, Wallström P, Peeters PH, Key TJ, Khaw KT, Wareham NJ, Freisling H, Stepien M, Ferrari P, Gunter MJ, Murphy N, Riboli E, González CA.(PubMed)