Epidemiological studies do not agreed that coffee and coffee caffeine may have potential in reduced risk and treatment of laryngeal cancer.
Laryngeal cancer is a medical condition of irregular cell growth in the tissues of the larynx. The cancer cells may spread to other tissues and organs in the late stage.
Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
In the review literatureof a total of 2,803 cases and 503,234 controls in 10 independent studies identified by searching electronic database (Medline and EMBASE) and reviewing the reference lists of relevant articles until Oct. 2013, researchers found that incidence of larygeal cancer was associated to coffee consumption, in compared to non drinkers. Intake of coffee showed a significant relative risk of RR = 1.47 in compared to base line.
Interestingly, researchers found, no statistically significant association of cancer incident difference in comparison between moderate and low coffee drinking .
According to the study, there was a evidence of statistically significant association of dose of coffee consumption and risk of laryngeal cancer.
Dr. Chen J, the lead researcher said, " A dose-response relationship between coffee intake and laryngeal carcinoma was detected" and "this meta-analysis of observational studies demonstrate that coffee consumption would increase the laryngeal cancer risk".
According to the result published, the study also identified that among the 6 studies that reported the association between coffee consumption and laryngeal carcinoma, only one study was a prospective population based cohort study, while the rest 5 studies were retrospective hospital based case-control studies using observation of returned survey from participants.
Contrastively, also in the searching of data base PubMed, Web of Knowledge and Wan Fang Med Online, identified 8 studies including 2167 laryngeal cancer cases, researchers insisted that there was insignificant association between coffee and coffee caffeine intake and risk of laryngeal cancer, regardless to volumes intake.
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Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Tea and coffee consumption and risk of laryngeal cancer: a systematic review meta-analysis by Chen J1, Long S1.(PMC)
(2) Association between tea and coffee consumption and risk of laryngeal cancer: a meta-analysis by Ouyang Z1, Wang Z2, Jin J1.(PubMed)