Good news for coffee lovers, intake of coffee daily and regularly showed to express a positive effect in reduced risk and progression of chronic hepatitis. a renowned institute joint study suggested.
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
Chronic hepatitis is a condition of liver inflammation caused by hepatitis B and C viruses and certain drugs, lasting at least 6 months.
In the study of 910 patients with chronic HCV infection, 98% male and 38% with advanced hepatic fibrosis with daily intake of caffeinated coffee higher among controls than patients with advanced fibrosis, researchers filed the following results
1. Coffee was one of most caffeine injected by participants in the control group.
2. Consumed 100 mg or more of caffeine daily from all sources was found in more participants on higher percentage of controls (66.0%) group in compared to patients with advanced fibrosis group.
3. Daily intake of 100 mg or more of caffeine also expressed a significant hepatoprotective effects in controls.
More importantly, Dr. Szántová M,, the lead author said,"(The liver protective activity of coffee against chronic hepatitis may be attributed to action in)modulation of genetic expression of key enzymes of fatty acid synthesis, modulation of mRNA included in autophagia, reduction of stress of endoplasmatic reticulum together with decrease of proinflammatory cytokines and decrease of fibrogenesis are main mechanisms" and " Coffee is non-pharmacological tool of primary and secondary prevention of chronic liver diseases".
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Coffee and Caffeine Are Associated With Decreased Risk of Advanced Hepatic Fibrosis Among Patients With Hepatitis C by Khalaf N1, White D1, Kanwal F1, Ramsey D1, Mittal S1, Tavakoli-Tabasi S2, Kuzniarek J3, El-Serag HB4.(PubMed)
(2) [Coffee as hepatoprotective factor].[Article in Czech] by Szántová M, Ďurkovičová Z.(PubMed)
(3) Coffee and liver health by Morisco F1, Lembo V, Mazzone G, Camera S, Caporaso N.(PubMed)