Coffee intake regularly may have a profound effect on development and progression of liver disease, a recent study suggested.
Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
Liver disease is a class of conditions, including, irrhosis, or scarring of the liver, inflammatory viral liver disease.....
According to the joint study led by the Fortis Escorts Liver and Digestive Diseases, coffee consumption showed a strong effect in reduced risk of liver diseases caused by Hepatitis B and C, as well as nonalcoholic fatty liver disease and alcoholic liver disease.
In a follow up study of 766 participants of the Hepatitis C Antiviral entered a Long-Term Treatment against Cirrhosis (HALT-C) trial with hepatitis C-related bridging fibrosis or cirrhosis on liver biopsy and failed to achieve a sustained virological response to peginterferon plus ribavirin treatment, researchers found that higher coffee consumption showed a significant in reduced progression of liver disease expressed with a relative risk ratio of 1.11 (0.76-1.61) for less than 1 cup/day; 0.70 (0.48-1.02) for 1 to fewer than 3 cups/day; and 0.47 (0.27-0.85) for 3 or more cups/day (P-trend = 0.0003) in compared to non drinkers.
Regular coffee consumption was associated with lower rates of disease progression also reported a large prospective study in participants with advanced hepatitis C-related liver disease.
More importantly, the retrospective cross-sectional study on patients different ltypes of liver disease, including non-alcoholic fatty liver disease (NAFLD), hepatitis C virus (HCV), and hepatitis B virus (HBV) infection, postulated that drinking over 2 cups of coffee per day showed a lower liver stiffness in compared to non drinking group.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Coffee and Liver Disease by Wadhawan M1, Anand AC2.(PubMed)
(2) Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C by Freedman ND1, Everhart JE, Lindsay KL, Ghany MG, Curto TM, Shiffman ML, Lee WM, Lok AS, Di Bisceglie AM, Bonkovsky HL, Hoefs JC, Dienstag JL, Morishima C, Abnet CC, Sinha R; HALT-C Trial Group.(PubMed)
(3) Coffee Intake Is Associated with a Lower Liver Stiffness in Patients with Non-Alcoholic Fatty Liver Disease, Hepatitis C, and Hepatitis B by Hodge A1,2, Lim S3, Goh E4, Wong O5, Marsh P6, Knight V7, Sievert W8,9, de Courten B10.(PubMed)
(4) Coffee and herbal tea consumption is associated with lower liver stiffness in the general population: The Rotterdam study by Alferink LJM1, Fittipaldi J2, Kiefte-de Jong JC3, Taimr P1, Hansen BE4, Metselaar HJ1, Schoufour JD5, Ikram MA6, Janssen HLA4, Franco OH5, Darwish Murad S7.(PubMed)