Coffee may have a profound effect in stimulated function of arteries and veins to provide nutrients and fluids to the body through blood and water circulation, a joint study suggested.
Vascular function is the action of arteries and veins, in imvolving blood and water circulation in the body.
Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.
According to the study lead by the University of Reading, chlorogenic acids isolated from coffee roasted bean, acutely improved vascular function, partly acting as a mediators mediated by 5-CQA in regulated the normal function of arteries and veins.
1. Low and high CGA(89 mg and 310 mg CGA) intake, showed a significant effect on vascular function 1 hour after injecting coffee
2. Coffee intake was found closely associated to the paralleled to the appearance of CGA metabolites in regulated the normal function of arteries and veins at 5 hours
1. Coffee consumption over the period indicated and after 1 hours showed a significant presence of caffeic and ferulic acid concentrations in the coffee-drinking groups, with different values in 2 coffee injection group.
2. In the same time as in 1, the levels of antioxidant expression increased substantially in 2 coffee intake group, but undetectable in control group or placebo.
3. All amount of antioxidants and phytochemicals creased to exist after 8 weeks.
The evidences in the study demonstrated a acute effect of coffee in promoting of vascular function in improved nutrients and fluids transportation by arteries and vessels.
Taking together, there is no doubt that coffee consumption have an enormous effect in improved vascular function in reduced risk of cardiovascular incidence and complications.
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(1) Mediation of coffee-induced improvements in human vascular function by chlorogenic acids and its metabolites: Two randomized, controlled, crossover intervention trials by Mills CE1, Flury A2, Marmet C3, Poquet L3, Rimoldi SF2, Sartori C4, Rexhaj E2, Brenner R2, Allemann Y2, Zimmermann D3, Gibson GR1, Mottram DS1, Oruna-Concha MJ1, Actis-Goretta L3, Spencer JP5.(PubMed)
(2) Coffee Consumption Increases the Antioxidant Capacity of Plasma and Has No Effect on the Lipid Profile or Vascular Function in Healthy Adults in a Randomized Controlled Trial by Agudelo-Ochoa GM1, Pulgarín-Zapata IC2, Velásquez-Rodriguez CM3, Duque-Ramírez M4, Naranjo-Cano M5, Quintero-Ortiz MM5, Lara-Guzmán OJ6, Muñoz-Durango K2.(PubMed)