Intake of dried peas daily and regularly may reduce risk and treatment of chronic inflammatory diseases, some institute studies suggested.
Dried pea is a small but nutritionally mighty member of the legume family, genus Pisum belongings to the family Fabaceae with healthy source of proteins, fibers, vitamins and minerals.
Inflammation is a natural process of the immune system to heal body damage and injure caused by invasion of foreign substances, including bacteria and virus.
In the study to evaluate the preventive effects of two pea (Pisum sativum) seed albumin extracts, either in the presence (pea seed extract [PSE]) or absence (albumin fraction from PSE [AF-PSE]) of soluble polysaccharides, in the dextran sodium sulfate (DSS) induced colitis in mice assigned to five groups: one noncolitic and four colitic, researchers found that
1. All treatment groups displayed a significantly intestinal anti-inflammatory effect, observed by reduced microscopic histological damage in comparison with nontreated mice
2. Peas extract treatment group was found to ameliorate pro inflammatory markers through regulating the colonic mRNA expression.
In other words, pea (Pisum sativum) seed albumin extracts not only inhibited auto immune response in expression of RNA in transmitting information to proteins involved production of pro inflammatory cytokins but also strengthened colonic cells in prevented permeation of noxious agents,
Other researchers, in a murine model. study to investigate the effect of enzymatic protein hydrolysates isolated from yellow pea seed in risk of inflammation showed that
2. Peas proetein also expressed a strong effect in regulate up-regulation of IL-6 secretion by small intestine epithelial cells (IEC), in reduced risk inflammation caused by B-cell terminal differentiation to IgA-secreting cells.
Interleukin 6 (IL-6) is an interleukin has a duo functions in activated either pro-inflammatory cytokine or anti-inflammatory myokine.
More importantly in the study to evaluate the anti-inflammatory and platelet aggregation effects of three medicinal plants of Pakistan. Methanolic extract of garden pea, researchers after considering to other con founders postulated that
Prostaglandin E2 (PGE-2) is another pro inflammatory protein with function in response to infection or inflammation produced by blood vessel walls.
Since all ingredients displayed a significant activity in protect the natural body defense mechanism for the removal of injurious agents, necrosed cells and tissues from the body without elevating the inflammatory production, Dr. Zia-ul-Haq M, the lead author said, " Garden pea, Desi chickpea and Kabuli chickpea could be useful as natural antithrombotic anti-inflammatory materials".
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Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Pea (Pisum sativum L.) seed albumin extracts show anti-inflammatory effect in the DSS model of mouse colitis by Utrilla MP1, Peinado MJ, Ruiz R, Rodriguez-Nogales A, Algieri F, Rodriguez-Cabezas ME, Clemente A, Galvez J, Rubio LA.(PubMed)
(2) Anti-oxidant, anti-inflammatory and immunomodulating properties of an enzymatic protein hydrolysate from yellow field pea seeds by Ndiaye F1, Vuong T, Duarte J, Aluko RE, Matar C.(PubMed)
(3) Platelet aggregation and anti-inflammatory effects of garden pea, Desi chickpea and Kabuli chickpea. by Zia-ul-Haq M1, Khan BA, Landa P, Kutil Z, Ahmed S, Qayum M, Ahmad S.(PubMed)