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Tuesday, 7 January 2014

Herbal Burdock and Cancer

Burdock is plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro. It has been used over thousand of years in Chins and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.
Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.

The ingredients
It contains carbonated water, sugar,, manloid colourings, phosphoric acid, citric acid and a good amount of dietary fiber, calcium, potassium, and amino acids and chemicals compounds of guaianolide, arctinone, arctinal, methyl arctate,11-tridecadien-3,5,7,9-tetraynde-hydrocostus lactone,dehydrodihydrocostus lactone, 3-octenoic acid, 3-hexenoic acid etc.

The benefits 
Arctium lappa or burdock has been used as a healthy and nutritive food in Chinese societies and  therapeutically in Europe, North America and Asia for hundreds of years.
Lappaol F, the chemicals constituents from plant Arctium Lappa L. Lappaol F suppressed cancer cell growth in a time- and dose-dependent manner in human cancer cell lines. In the evaluation the cytotoxicity profiles of the extract of Arctium lappa L using various cancer and normal cell lines, arctigenin, showed cytotoxicity to lung cancer (A549), liver cancer (HepG2) and stomach cancer (KATO III) cells, while no cytotoxicity to several normal cell lines. Its antioxidants and antidiabetic compounds found in the root and some active compounds in the seed possessed anti-inflammatory effects and potent inhibitory effects on the growth of tumors.

The Side effects
1. Overdose can be poisoning and may lead to symptoms of
acute poisoning include phenothiazines, tricyclic antidepressants, and antihistamines.
2. It may cause dermatitis and allergic/inflammatory responses to certain people with contact as a result of lactones which the plant produces.
3. Do not use burdock if you are pregnant or breast feeding.
4. Etc.

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References
(1) Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L by Sun Q, Liu K, Shen X, Jin W, Jiang L, Sheikh MS, Hu Y, Huang Y.(PubMed)
(2) Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L by Susanti S, Iwasaki H, Itokazu Y, Nago M, Taira N, Saitoh S, Oku H.(PubMed)
(3) A review of the pharmacological effects of Arctium lappa (burdock) by Chan YS, Cheng LN, Wu JH, Chan E, Kwan YW, Lee SM, Leung GP, Yu PH, Chan SW.(PubMed)