Cancer is a class of diseases in which a group of cells growing and multiplying disordered and uncontrollable way in our body, have become progressively worse and damaged other healthy tissues, sometimes spreads to other organs in the body via lymph or blood and results may be in death.
Gastric Cancer is defined as a condition of the abnormal proliferation of cells in the Gastrointestinal Tract.
Nutrients and Chemicals constituents a. Nutrients
2. Dietary fiber
5. Vitamin A
6. Vitamin B
8. Vitamin C
b. Chemicals constituents
Infection with Helicobacter pylori leads to gastritis, peptic ulcers and gastric cancer. The major chemical compounds of black bean include anthocyanin, (-)-epicatechin, delphinidin, petunidin, flavonols and malvidin.
Anthocyanins, the major chemical compounds of black soybean not only decrease H. pylori-induced ROS enhancement, but also inhibited phosphorylation of mitogen-activated protein kinases, translocation of nuclear factor-kappa B and Iκβα degradationnd H. pylori-induced inducible nitric oxide synthases and cyclooxygenase-2 mRNA expression and IL-8 production by 45.8%. On the other hand, in the study by Dr, Zou Y, and Dr. Chang SK. indicated that black soybean extract inhibited AGS cell growth in a dose-dependent manner with an IC(50) of 3.69 mg/m and suggested that black soybean extract could be used as an apoptosis inducer in AGS cells and a natural chemopreventive agent in the treatment of human gastric cancer.
The Side effect
Black beans contain purines, excessive intake of these substances can cause the accumulation of uric acid, leading to"gout" and kidney stones.
References (1) Differential accumulation of polyphenolics in black bean genotypes grown in four environments.
Marles MA, Balasubramanian P, Bett KE. (PubMed)
(2) Anthocyanins from black soybean inhibit Helicobacter pylori-induced inflammation in human gastric epithelial AGS cells.