Wednesday, 1 January 2014

Food therapy - Black beans (Phaseolus) and Prostatic hyperplasia

Black bean is a Small roughly ovoid legumes with glossy black shells, genus Phaseolus, belongs to the family Fabaceae and can bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.
Prostatic hyperplasia is a condition of enlarged prostate. Starting at age 40, the levels of the by-product prolactin of testosterone of men increases, stimulating the production of the enzyme 5-alpha reductase that causes the conversion of testosterone to gihydro-testosterones DHT triggering prostate enlargement and other problems. Therefore in order to prevent the symptoms of enlarged prostate is to naturally impend the conversion of testosterone to DHT. Unfortunately, aging is not the only cause of enlarged prostate. In this article, we will discuss other causes of prostate enlargement.

Nutrients and Chemicals constituents a. Nutrients
1. Carbohydrate
2. Dietary fiber
3. Protein
4. Fat
5. Vitamin A
6. Vitamin B
7. Folate
8. Vitamin C
9. Calcium
10. Magnesium
11. Manganese
12. Phosphorus
13. Molybdenum
14. Iron
10. Etc.
b. Chemicals constituents
The major chemical compounds of black bean include anthocyanin, (-)-epicatechin, delphinidin, petunidin, flavonols  and malvidin.

The benefits
As a result of prosperity in the emerging world, Prostatic hyperplasia has become a medical condition of which requires urgent attention. Anthocyanin, a major chemical compound found in  pigment in black bean may be a potential food used to treatment for enlarged prostate, as anthocyanin  decrease the volume and suppressing the proliferation of the prostate. But further studies are needed to better understand the mechanisms and actions of anthocyanin, and these studies may lead to the clinical application of anthocyanin in treating BPH. Other study in the investigation the effects of anthocyanin extracted from black soybeans on a rat model of benign prostatic hyperplasia (BPH), Prostate hyperplasia was induced by the administration of testosterone propionate for 4 weeks of that led to prostatic hyperplasia,  anthocyanin administration helped to prevent this change. Apoptotic body counts were significantly higher in groups receiving anthocyanin than in the BPH-induced group (p < 0.05).

The Side effect
1. Purines
Black beans contain purines, excessive intake of these substances can cause the accumulation of uric acid, leading to"gout" and kidney stones.
2. Etc.

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(1) Differential accumulation of polyphenolics in black bean genotypes grown in four environments.
Marles MA, Balasubramanian P, Bett KE. (PubMed)
(2) Conservative treatment of benign prostatic hyperplasia].[Article in Hungarian] by Romics I.(PubMed)
(3) Anthocyanin extracted from black soybean reduces prostate weight and promotes apoptosis in the prostatic hyperplasia-induced rat model. by Jang H, Ha US, Kim SJ, Yoon BI, Han DS, Yuk SM, Kim SW.(PubMed)