Arctostaphylos uva-ursi is one of the species of Bearberry, in the genus Arctostaphylos, belonging to the family Ericaceae, native to the
northern North America, Asia and Europe. The herb has been used in
traditional medicine as diuretic agent and to treat urinary problems,
including bladder infections, kidney infection, kidney stone, pelvic
pain, etc.
Bladder
cancer is most common type of cancer that effect men twice as
frequently as it effects women. Usually it starts from the lining the
bladder caused by several types of malignant growths of the urinary
bladder cells.
The Ingredients
It contains arbutin, ursolic acid, tannic acid, gallic acid, some
essential oil and resin, hydroquinones tannins, phenolic glycosides and
flavonoids.
The benefits
The search for alternative medicine for treatment of cancers has been
growing worldwide, and herbs used in folk medicine may be a potential
sources as it induced little or no side effects. Arbutin, a glycosylated
hydroquinone extracted from the bearberry plant (Arctostaphylos
species), is found significantly decreased TCCSUP human bladder cell
proliferation in a concentration- and time-dependent manner by
increased the expression of p21WAF1/CIP1 (p21), which involved in cell
cycle regulation.
The Side effect
1. Overdoses may cause gastrointestinal discomfort, including cause
nausea, vomiting, etc. and fever, chills, severe back pain, ringing in
the ears, etc.
2. The herb may interact with other medicine, including diuretic
3. Do not use the herb in new born, children or if you are pregnant or
breast feeding without approval from the related field specialist.
4. Etc.
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References
(1) Arbutin inhibits TCCSUP human bladder cancer cell proliferation via
up-regulation of p21 By Li H, Jeong YM, Kim SY, Kim MK, Kim DS.(PubMed)
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
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