Mushroom may be the next generation of vegetable processing pharmaceutical value for the finding of single ingredients that process anti-breast cancer potency, some studies suggested.
Breast cancer is a primary medical and chronic condition that starts with the irregular cells growth due to DNA alternation on the surface the inner lining of the breast tissue.
At the advanced stage, breast cancer cells can travel a distance away to infect other healthy tissue and organ.
According to the statistic, the risk of a woman to develop breast cancer in her lifetime is 12.4%.
In 2018, approximately over 260,000 new cases of invasive breast cancer are expected to be diagnosed in women in the U.S., along with over 63,000 new cases of non-invasive (in situ) breast cancer.
The exact causes of breast cancer are unknown, Women who carry the mutated gene BRAC1 and 2 are associated with the increased risk of the disease.
In the concerns of breast cancer risk among women in both developed and less-developed countries and the increasing rates of breast cancer worldwide, particularly in postmenopausal and estrogen receptor-positive cases, researchers at the University Hospital of South Manchester NHS Foundation Trust, launched an investigation to evaluate whether diet and lifestyle can prevent breast cancer.
Mushroom is a standard name of white button mushroom, the fleshy, spore-bearing fruiting body of a fungus produced above ground on soil or on its food source,
The vegetable is a genus A. Muscaria and belonging to the family Amanitaceae and cultivated in many cultures all over the world for foods and health benefits.
Chemical constituents of white button mushroom include astraodorol, Psilocybin, Lectin, adustin, ribonuclease, nicotine, 2-hydroxy-4-methoxy-6-methylbenzoic acid, orsellinic acid, melleolide, ergosterol, genistein, daidzein, daucosterol, genistin, uracil and D-mannitol(a).
In the assessment of white button mushroom (WBM), widely consumed in most countries intake in the protection of breast cancer, researchers launched an investigation to examine mushroom polysaccharides for their immunomodulating and antitumor properties.
PAP-3 also exhibited the pro-apoptotic function of p53, and cell cycle arrest at the S phase.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(a) [Chemical constituents from fungus Armillaria mellea]. by [Article in Chinese] by Yuan XL1, Yan LH, Zhang QW, Wang ZM.(PubMed)
(1) Macrophage immunomodulating and antitumor activities of polysaccharides isolated from Agaricus bisporus white button mushrooms by Jeong SC1, Koyyalamudi SR, Jeong YT, Song CH, Pang G.(PubMed)
(2) ROS-dependent mitochondria molecular mechanisms underlying antitumor activity of Pleurotus abalonus acidic polysaccharides in human breast cancer MCF-7 cells by Shi X1, Zhao Y, Jiao Y, Shi T, Yang X.(PubMed)
(2) Commonly consumed and specialty dietary mushrooms reduce cellular proliferation in MCF-7 human breast cancer cells by Martin KR1, Brophy SK.(PubMed)
(3) Can diet and lifestyle prevent breast cancer: what is the evidence? by Harvie M1, Howell A1, Evans DG. (PubMed)