Allicin, a bioactive compound found abundantly in garlic and onion may be the next pharmaceutical target to identify the single ingredient medicine for the treatment of cardiovascular disease, some scientists suggested.
Cardiovascular diseases are a class of chronic and medical conditions of heart and blood vessel disease related to the plaque build up in the walls of the arteries that cause the blockage of blood flow and reduced the oxygen and nutrients rich blood to reach the heart, leading to heart attack and stroke,
High levels of bad cholesterol (LDL) build up in the arteries as a result of uncontrolled diet with high levels of saturated fat and trans fat.
All these add to the formation of atherosclerosis lesions and eventually arterial blockage or anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease.
Allicin is phytochemical containing sulfur in the class of organosulfur compound, found abundantly in onion and garlic.
In the concerns of hyperlipidemia.cause of cardiovascular disease, researhcer at the Taishan Medical University, conducted an investigation to test the effects of combination therapy of allicin and fenofibrate on the endothelial and liver functions in rats.
At the final phase, compared with high fat diet control, fenofibrate alone or the combined therapy increased remarkably the levels of high-density lipoprotein respectively (P<0.05).
Additionally, in the search of chemicals that arise from natural food source with the potential to provide beneficial effects to the cardiovascular system, researchers at the heart team at The Hong Kong Polytechnic University launched a study to test the effect of allicin om heart diseases.
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Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(3) The effect of combination therapy of allicin and fenofibrate on high fat diet-induced vascular endothelium dysfunction and liver damage in rats BY Li W, Wang D, Song G, Zuo C, Qiao X, Qin S.(PubMed)
(4) A review of the cardiovascular benefits and antioxidant properties of allicin by Chan JY, Yuen AC, Chan RY, Chan SW.(PubMed)
(5) An index of unhealthy lifestyle is associated with coronary heart disease mortality rates for small areas in England after adjustment for deprivation by P. Scarborough,⁎ S. Allender, M. Rayner, and M. Goldacre. (PMC)