Intake avocado daily may have a strong effect in reducing the risk of acute and chronic inflammation, some researchers suggested.
Inflammation is a natural and systematic immune response with an aim to protect our body against the invasion of foreign pathogens.
Acute inflammation is caused by overproduction of proinflammatory cytokines which is activated the immune macrophages, a first line of the immune defense.
Some researchers suggested that long-term exposure to lower levels of irritants, such as industrial chemicals or polluted air may also cause chronic inflammation.
According to the statistic, in 2000, nearly 125 million Americans were living with chronic conditions and 61 million (21%) had more than one. And these numbers are expected to increase substantially,
More scarcely, 3 of 5 people die due to chronic inflammatory diseases like stroke, chronic respiratory diseases, heart disorders, cancer, obesity, and diabetes, worldwide.
If you experience symptoms of depression, anxiety and mood disorders, persistent gastrointestinal complications like constipation, diarrhea, and acid reflux, weight gain, and frequent infections, you may be at the early stage of the development of chronic inflammation. Please check with your doctor to rule out the possibility.
Dr. Roma Pahwa and Dr. Ishwarlal Jialal in the article of chronic inflammation suggested that many dietary and lifestyle changes may be helpful in removing inflammation triggers and reducing chronic inflammation as listed below. The most effective is weight loss.
In the finding a natural ingredient for the treatment of skin inflammation caused by exposure to ultraviolet (UV) radiation without inducing side effects, researchers at the Granot Initiative Center conducted a study to test the ability of unique lipid molecules, polyhydroxylated fatty alcohols (PFA), extracted from avocado, to reduce UVB-induced damage and inflammation in skin.
Introducing PFA to keratinocytes prior to their exposure to UVB exerted a protective effect, increasing cell viability, decreasing the secretion of IL-6, and PGE(2), the proinflammatory cytokines and enhancing DNA repair.
In human skin explants, treating with PFA reduced significantly UV-induced cellular damage.
* ASU reduced proinflammatory cytokines, TNF-alpha, IL-1beta, COX-2, and iNOS expression in LPS-activated chondrocytes to levels similar to nonactivated control levels.
* The suppression of COX-2 and iNOS expression was paralleled by a significant reduction in PGE(2) and nitrite, respectively.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Polyhydroxylated fatty alcohols derived from avocado suppress the inflammatory response and provide non-sunscreen protection against UV-induced damage in skin cells by Rosenblat G1, Meretski S, Segal J, Tarshis M, Schroeder A, Zanin-Zhorov A, Lion G, Ingber A, Hochberg M.(PubMed)
(2) Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate by Heinecke LF1, Grzanna MW, Au AY, Mochal CA, Rashmir-Raven A, Frondoza CG.(PubMed)
(3) Avocado soybean unsaponifiables (ASU) suppress TNF-alpha, IL-1beta, COX-2, iNOS gene expression, and prostaglandin E2 and nitric oxide production in articular chondrocytes and monocyte/macrophages by Au RY1, Al-Talib TK, Au AY, Phan PV, Frondoza CG.(PubMed)
(4) Chronic Inflammation by Roma Pahwa; Ishwarlal Jialal. (NCBI)