Apricot, a functional food may be the next pharmaceutical target for the finding of an effective medicine with potential in the treatment of liver cancer, some scientists suggested.
The apricot tree is about 8–12 m tall and a trunk up to 40 cm diameter belonging to the family Rosaceae.
Apricot is classified in the family of the plum with yellow to orange, often tinged red on the side which is exposed to the sun.
Chemical constituents of apricot include
Oleic acid, linoleic acid, palmitic.acid, glycolipids, phospholipids, benzoic acid (I), isorhamnetin (II), quercetin (III), kaempferol-3-O-beta-D-galactopyranoside (IV), isorhamnetin-3-O-beta-D-glucopyranoside (V), isoquercitrin (VI), hypericin (VII) and rutin (VIII)(a) and flavonoid glycosides.
In the assessment of MK615, an anti-cancer substance extracted from the Japanese apricot, researchers at the Dokkyo University School of Medicine conducted an investigation to examine the anti-neoplastic effect of MK615 against hepatocellular carcinoma (HCC).
* MK615 inhibited the growth of, and lysed, HuH7 and Hep3B cells in a dose-dependent manner
* MK615 decreased the population of cells in G2/M phase, according to the Cell cycle analysis.
* Administration of chemo drug Sorafenib was not effective.
However, further data collection large example size and multi-centers studies performed with human consumption of the whole food apricot during the course of the disease will be necessary to complete the picture of apricot anti-liver cancer possibilities.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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(2) Advanced hepatocellular carcinoma responds to MK615, a compound extract from the Japanese apricot "Prunus mume" by Hoshino T1, Takagi H, Naganuma A, Koitabashi E, Uehara S, Sakamoto N, Kudo T, Sato K, Kakizaki S.(PubMed)