Aloe Vera may be the next target for the pharmaceutical companies to extract a single ingredient for the treatment of cancers, some scientists suggested.
Cancers are a class of medical diseases associated with cell growth irregularly and disorderly in some specific tissue and organs.
Most cancer starts at the cell on the surface of the inner lining of organ's tissue. At the later stage, cancer cells can be found in the deeper of layers of the infected organ.
In the advanced stage, malignant cells can travel a distance away from the original site to infect other healthy tissue and organ through the circulation of fluids and blood.
The causes of cancer are the results of the alternation of healthy cell DNA. Researchers do not why the health cells DNA are alternated.
Normally, healthy cells undergo a certain number of cell cycle divisions than die. In a cancerous cell, cell division undergoes indefinitely.
According to the statistic, approximately 38.4% of men and women will be diagnosed with cancer at some point during their lifetimes.
The genetic mutation of the cancer cell may be associated with certain risk factors. Epidemiological studies suggested that long-term exposure to carcinogens, the increased in age, gender, inherited genetic defects and skin type can increase the risk the cancer onset.
"Overall, 17,340 PVs were identified in 17,000 (6.7%) of the tested individuals. The pathogenic variants (PV) positive rate was 9.8% among individuals with a personal cancer history, compared to 4.7% in unaffected individuals. PVs were most common in BRCA1/2 (42.2%), other breast cancer (BR) genes (32.9%), and the LS genes (13.2%)".
Aloe vera has been used in herbal medicine in treating many kinds of disease, including wound, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated of cholesterol, etc.
It is also one of many popular herbs studied in scientific ways with some conflicting results.
The ten main areas of chemical constituents of Aloe vera are amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharide, polysaccharides, salicylic acid, saponins, and sterols.
They all work together in a synergistic way to create healing and health-giving benefits, according to Gertrude Baldwin in the article of THE BENEFITS OF THE USE OF ALOE VERA IN HERBAL PREPARATIONS.
In the finding, a natural ingredient for the treatment of breast cancer without inducing side effects, researchers at the National Chung Hsing University conducted a study to compare the efficacy of Emodin and Aloe-Emodin, the major bioactive compound found in herbal Aloe Vera.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) ALOE VERA by Gertrude Baldwin, http://www.herballegacy.com/Baldwin_Chemical.html
(2) Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER α Inhibition.
Huang PH, Huang CY, Chen MC, Lee YT, Yue CH, Wang HY, Lin H.(PubMed)
(3) Growth inhibitory effects of gastric cancer cells with an increase in S phase and alkaline phosphatase activity repression by aloe-emodin. by Guo J, Xiao B, Zhang S, Liu D, Liao Y, Sun Q.(PubMed)
(4) Anticancer effect of aloe-emodin on cervical cancer cells involves G2/M arrest and induction of differentiation. by Guo JM, Xiao BX, Liu Q, Zhang S, Liu DH, Gong ZH.(PubMed)
(5) Clinical testing with a panel of 25 genes associated with increased cancer risk results in a significant increase in clinically significant findings across a broad range of cancer histories by (Research Gate)