Scientists may have found a natural ingredient for the prevention and treatment of colon cancer with no side effects, according to studies.
Colon cancer is relatively very common and slowly growing and progressing in a predictable way.
Most cases primary colon cancer start in the cell on the surface of the inner lining of the colon. At the early stage. most patients with colon cancer do not experience any symptoms.
However, at the advanced stage, the tumor not only can spread to other healthy tissue and organs a distance away through blood and fluid circulation but also suppress the nearby tissue and nerve cells.
The progression of colon cancer at this stage not only induces symptoms of the change in bowel habits, the change in the consistency of your stool, that lasts longer than four weeks but also causes rectal bleeding and persistent abdominal severe pain.
According to the statistic by the American Cancer Society, in the US, there are
97,220 new cases of colon cancer diagnosed in 2018. The lifetime risk of developing colorectal cancer is 1 in 22 (4.49%) for men and 1 in 24 (4.15%) for women.
The causes of colon cancer are unknown but certain risk factors, such as genetic preposition and chronic inflammation induced by colonic diseases are associated with the onset of the disease.
Some researchers suggested that the widespread of colon cancer over the past few decades probably associated with the promotion of the Western diet.
According to an article posted on WebMD By Salynn Boyles, the author said, "While there is no shortage of evidence linking the so-called Western diet to an increased risk for developing colon cancer, the study is among the first to examine the impact of such a diet on survival among patients treated for the disease".
And, "The findings must be confirmed, but Dana-Farber Cancer Center oncologist Jeffrey Meyerhardt, MD, a researcher on the team, says they cannot be ignored by colon cancer patients or their physicians".
The statement clearly suggested that by making a change to a healthy diet, the risk of colon cancer can be reduced substantially.
Dithiolthiones are phytochemicals in the class of Organosulfides, found abundantly in cruciferous vegetables, garden sorrel, horseradish, etc.
On finding a natural bioactive compound for the treatment of colon cancer with no side effects, researchers looked into sulforaphane is an isothiocyanate that is present naturally in widely consumed vegetables and has a particularly high concentration in broccoli in the risk of colon cancer.
The formula exerted a significant antiproliferative activity on all tested cancer cell lines (PC3, MCF7, and SW480), as well as on the EA.hy 926 endothelial cell line in a dose-dependent manner.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells by Gamet-Payrastre L1, Li P, Lumeau S, Cassar G, Dupont MA, Chevolleau S, Gasc N, Tulliez J, Tercé F.(PubMed)
(2) GE132+Natural: Novel promising dietetic supplement with antiproliferative influence on prostate, colon, and breast cancer cells by Okic-Djordjevic I1, Trivanovic D, Krstic J, Jaukovic A, Mojsilovic S, Santibanez JF, Terzic M, Vesovic D, Bugarski D.(PubMed)
(3) HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates by Rajendran P1, Kidane AI, Yu TW, Dashwood WM, Bisson WH, Löhr CV, Ho E, Williams DE, Dashwood RH.(PubMed)
(4) ‘Western’ Diet Tied to Colon Cancer By Salynn Boyles (WebMD)