Monday, 17 December 2018

Ginger, the Potential Remedy for the Prevention and Treatment of Atherosclerosis with No Side Effects

By Kyle J Norton

Ginger may have a potential and profound effect in blocking the accumulation of plaques on the arterial wall in initiating the risk of atherosclerosis,  some scientists suggested.

Atherosclerosis is a medical condition associated with plaque building up in the arteries, leading to the narrowing the arterial function in the transportation of oxygenated blood to the heart and other blood of the body.

Plaques are substance made up from the accumulated fat, cholesterol, calcium, and other substances found in the blood, including cadmium.

Long-term accumulation of plaque can also cause hardening and stiffing arterial wall can lead to the blockage of the arteries and risk of heart disease depending on the location of the blockage.

Most people in the early stage of atherosclerosis do not experience any symptoms. However, as the condition progresses and the location affected, patients may develop chest pain, shortness of breath, sweating, and anxiety.

Most common causes of atherosclerosis are the imbalance of the ratio of bad cholesterol and good cholesterol in the blood, long-term smoking, obesity, increase in age, obesity and some medical conditions, such as diabetes and high blood pressure.

Therefore adding a portion of olive oil into your daily diet can reduce the risk of high blood cholesterol

Dr. Siasos G, the lead scientists in the heart disease team in the concerns of the smoking detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease said, " smoking is an important modifiable risk factor for the development of cardiovascular disease,....via initiation and progression of atherosclerosis".

And, " variety of studies has proved that cigarette smoking induces oxidative stress, vascular inflammation, platelet coagulation, vascular dysfunction and impairs serum lipid profile in both current and chronic smokers, active and passive smokers and results in detrimental effects on the cardiovascular system".

The statement clearly indicated that cigarette smoking has a strong implication of the onset and progression of atherosclerosis.

Some researchers suggested that cigarette smoke contain a high amount of toxic chemicals that cause inflammation and formation of blood clot in the arteries and oxidation of low-density lipoprotein cholesterol.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

On finding a natural ingredient or whole food for the prevention and treatment, researchers at the joint study led by the University of Sistan and Baluchestan examined the potential protective effects of ginger in atherosclerosis and atherosclerotic cardiovascular disease.

The randomized, experimental, and controlled study included thirty healthy overweight women aged 20-30 years randomly divided into three equal groups, namely, ginger, ginger + high-intensity interval training (HIIT), and placebo + HIIT.

The training groups performed high-intensity interval exercises (i.e. 40-m maximal shuttle run) for ten consecutive weeks. The supplement groups daily took 3 g of ginger pills and the third group took the placebo.

The paired t-test revealed a significant decrease in the density of type 1 monocytes chemotactic protein (MCP-1) in HIIT + ginger (P = 0.026) and HIIT + placebo (P = 0.001) groups, an indication of reduced inflammation.

These results suggested that the relative and efficient role of HIIT combined with the ginger supplement in overweight women in inducing antioxidant/anti-inflammatory activity against atherosclerosis.

Furthermore, the investigation of the effects of air-dried ginger powder (0.1g/kg body weight, po, for 75 days) was carried out by the RNT Medical College, on experimentally induced atherosclerosis in rabbits by cholesterol feeding (0.3g/kg body weight, po).

Before administration of ginger powder, cholesterol feeding for 75 days led to the distinct development of atheroma in the aorta and coronary arteries of the rabbits.

The accumulation of plaque in the arteries was significantly inhibited by about 50% following ginger administration.

Moreover, ginger treatment also decreases lipid peroxidation and enhanced fibrinolytic activity associated to dissolve blood clots.

The findings indicated that ginger distinct protection from the development of atherosclerosis is attributed probably because of its free radical scavengings, prostaglandin inhibitory and fibri 

Taken altogether, ginger may be considered a functional food for the prevention and an adjunct therapy for the treatment of atherosclerosis without inducing any adverse effects.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.

(1) Spices and Atherosclerosis by Tsui PF1,2, Lin CS3, Ho LJ4, Lai JH. (PubMed)
(2) The effect of a 10-week high-intensity interval training and ginger consumption on inflammatory indices contributing to atherosclerosis in overweight women by Nayebifar S1, Afzalpour ME2, Kazemi T3, Eivary SH4, Mogharnasi M2. (PubMed)
(3) Protective effect of ginger, Zingiber officinale Rosc on experimental atherosclerosis in rabbits by Verma SK1, Singh M, Jain P, Bordia A.(PubMed)
(4) Smoking and atherosclerosis: mechanisms of disease and new therapeutic approaches by Siasos G, Tsigkou V, Kokkou E, Oikonomou E, Vavuranakis M, Vlachopoulos C, Verveniotis A, Limperi M, Genimata V, Papavassiliou AG, Stefanadis C, Tousoulis D. (PubMed)

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