Wednesday, 26 December 2018

Ginger, The Best Functional Food For Symptoms of Nausea and Vomiting

By Kyle J Norton

Scientists may have discovered a pungent and kitchen spice which processes a significant effect in reducing nausea and vomiting with no side effects, according to some studies.

Nausea and vomiting are the natural protection of the digestive system reacted to many causes, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer, or bulimia.

Morning sickness or nausea and vomiting are common experiences in pregnancy, affecting 70–80% of all pregnant women.

Nausea and vomiting that often develop by five to six weeks of pregnancy are the results of the rise of the hormone estrogen in the early stage of pregnancy. The syndrome may get even worse in women have a sensitive stomach which tries to adapt to the changes of pregnancy.

Morning sickness in the pregnancy may seem obvious in general population, however in a group of women with severe nausea and vomiting during pregnancy due to hyperemesis gravidarum (HG), an entity distinct from nausea and vomiting of pregnancy (NVP),  may lead to significant maternal and fetal morbidity if untreated.

Dr.Noel M. Lee, the lead author at the University of Wisconsin School of Medicine and Public Health in the study " Nausea and Vomiting of Pregnancy" said, "Various metabolic and neuromuscular factors have been implicated in the pathogenesis of NVP and HG; however, their exact cause is unknown. Consequently, treatment of NVP and HG can be difficult as neither the optimal targets for treatment nor the full effects of potential treatments on the developing fetus are known".

Where hyperemesis gravidarum (HG) is a pregnancy complication characterized by severe nausea, vomiting, weight loss, and possibly dehydration.

Other causes of nausea and vomiting are due to the prolonged period exposure to stress and long-term fatigue.

Patients who are having chemotherapy are associated with an increased risk of nausea and vomiting because of the injection of chemo drugs can affect parts of the stomach and brain that detect toxic (poisonous) substances.

Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.

The pungent spice has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.

With an aim to clarify the effect of ginger extract in treating chemotherapy-induced nausea and vomiting (CINV), a joint study led by Taipei Medical University-Shuang Ho Hospital was conducted to determine whether ginger could be used to treat CINV, which was interpreted using the PICOS (patient, problem/population, intervention, comparison, outcome, study) framework, with P being patients who underwent chemotherapy.

After searching the studies in English from 2000 to 2017 databases. 2 on a total of 10 studies with complete data. was included in the meta-analysis using Comprehensive Meta-analysis.

Ginger exerted a significant effect in reducing the symptoms of nausea and vomiting with the odds ratio (OR) of 0.71 

Further analysis also discovered that ginger could only reduce acute CINV in patients, particularly acute vomiting.

After taking additional ]assessment of the co and confounders, Dr. Chang WP the lead scientist said, "Ginger displayed significant efficacy with regard to controlling CINV in the experimental groups".

In the reaffirming the effect of ginger in the early pregnancy symptoms of nausea and vomiting of pregnancy (NVP), a joint study led by the Iran University of Medical Sciences launched an evaluation to compare the effects of ginger, pyridoxine (vitamin B6), and placebo.

The triple blind clinical trial on pregnant women suffering mild to moderate NVP between 6 and 16 weeks of pregnancy. 

In these women ginger, 500 mg twice daily, vitamin B6 40 mg twice daily and placebo twice daily were administered for 4 d.

The severity of NVP was evaluated 24 h before entering the study and up to 4 d after using medications and results were compared among the three groups.

The women of the three groups did not have significant differences according to age, gestational age, parity, and severity of each symptom before treatment and educational status.

After assessing the returned questionnaires, researchers indicated
* Ginger and vitamin B6 could reduce the severity of all items of Rhodes questionnaire significantly.

* Ginger and vitamin B6 were more effective than placebo

* total score of Rhodes did not show a significant difference between ginger and vitamin B6 (p = .128). Ginger was more effective for nausea (intensity and distress).

These results once against illustrate the efficacy of ginger in the treatment of nausea and vomiting in early pregnancy.

Taken altogether, there is no doubt that ginger may be used as a functional food for the treatment of nausea and vomiting in both early pregnancy and side effects of chemo treatment.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) A Meta-analysis of 10 Randomized Controlled Trials by Chang WP1, Peng YX.(PubMed)
(2) A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP) by Sharifzadeh F1, Kashanian M1, Koohpayehzadeh J2, Rezaian F1, Sheikhansari N3, Eshraghi N. (PubMed)
(3) Nausea and Vomiting of Pregnancy by Noel M. Lee, M.D., Gastroenterology Fellow and Sumona Saha, M.D., Assistant Professor of Medicine. (PMC)

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