Thursday, 20 December 2018

Papaya, The Fruit Which Normalizes Your Blood Pressure with No Side Effects

By Kyle J. Norton

Papaya may be considered a natural whole food for the prevention and treatment of hypertension, some scientists suggested.

Hypertension is another term of abnormally high blood pressure in the arteries.

Although h blood pressure usually does not cause symptoms some patients with the syndrome may experience dizziness and light head.

Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood.

Underlying medical conditions such as kidney disease and long=term stress are associated with high blood pressure. Epidemiological studies strongly suggested that poor lifestyle habits, such as an unhealthy diet, obesity and lack of exercise, are some major risk factors which can contribute to the early onset of high blood pressure.

Some researchers also found that excessive energy intake and obesity are major causes of hypertension. Dr. Savica V, the lead author in the study "The effect of nutrition on blood pressure" wrote, "Obesity is associated with increased activity of the renin-angiotensin-aldosterone and sympathetic nervous systems, possibly other mineralocorticoid activity, insulin resistance, salt-sensitive hypertension, and excess salt intake, and reduced kidney function".

High sodium chloride intake strongly predisposes to hypertension".

"Increased alcohol consumption may acutely elevate blood pressure. High intakes of potassium, polyunsaturated fatty acids, and protein, along with exercise and possibly vitamin D, may reduce blood pressure".

In the review of all the causable risk factors, you may find that the only natural way to prevent and treat hypertension is to follow a diet with a high intake of fruits and vegetable and whole grain and less in saturated and trans fat, red meat and processed food accompanied with a healthy lifestyle and moderate exercise.

Conventional hypertensive medications have undoubtedly prevented many deaths from heart disease in the past 30 years, but they have many side effects.

If you current taking hypertensive medicine, please make sure you know all the side effects for the preventive measure.

Papaya is a species of Carica Papaya, belongs to the family Caricaceae and native to the tropics of the Americas, and was first cultivated in Mexico and several centuries

Chemical constituents

Alkaloids, Cardenolides, Anthraquinones, Saponins, Tannin, phenol, flavonoid, anthocyanin, Benzyl glucosinolate, benzylisothiocyanate, 5-(Hydroxymethyl)-2-furancarboxaldehyde, 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one and 1,3-dihydroxy-2-propanone, etc.(a)

Malaysian plants pucuk ubi (Manihot esculenta), pucuk betik (Carica papaya), Ulam Raja (Cosmos caudatus), pegaga (Centella asiatica) and kacang botol (Psophocarpus tetragonolobus) was selected to the examine their effects on key enzymes related to type 2 diabetes and hypertension.

The hexane extract of pucuk ubi (95.01%) and dichloromethane extract of kacang botol (38.94%) showed the highest inhibitory potential against alpha-glucosidase in the alpha-glucosidase inhibition assay.

Furthermore, in the iACE inhibition assay, the inhibitory potential was highest in hexane extract of pegaga (48.45%) and dichloromethane extract of pucuk betik (59.77%).

These results suggested that papaya may have a nutraceutical potential for hyperglycemia and hypertension prevention associated with type 2 diabetes.

Male albino Wistar rats randomly were divided into three batches (15 rats per batch)-renal, DOCA-salt hypertensives, and the study to examine the antihypertensive effect of crude ethanol extract from the unripened fruit of Carica papaya.

Each batch was further divided into three groups-the untreated, hydrallazine and extract treated groups.

Before injection of crude ethanol extract, the basal (control) The mean arterial blood pressure (MAP) was 93.8 +/- 4.5, 175.2 +/- 5. 1 and 181.3 +/- 6.2 mmHg in the normotensive, renal and DOCA-salt hypertensives, respectively.

Groups treated with extract produced about 28% more depression of MAP than hydrallazine in the hypertensive groups treated with hydrallazine (200 microg/100 g i. v) and extract (20 mg/kg.i.v).

In vitro, using isolated rabbit arterial (aorta, renal and vertebral) strips showed that the papaya extract (10 microg/mL) produced relaxation of vascular muscle tone.

According to the findings, the fruit juice of C. papaya probably processes antihypertensive agent(s) which exhibits mainly alpha-adrenoceptor activity.

Taken all together, unripe fruit of papaya may have a significant effect in reducing the risk of hypertension and treatment of hypertension with no side effect.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(a) Chemical composition and bioactivity of dried fruits and honey of Ficus carica cultivars Dottato, San Francesco and Citrullara by Loizzo MR1, Bonesi M, Pugliese A, Menichini F, Tundis R.(PubMed)
(1) In vitro inhibitory potential of selected Malaysian plants against key enzymes involved in hyperglycemia and hypertension by Loh SP1, Hadira O.(PubMed)
(2) Blood pressure depression by the fruit juice of Carica papaya (L.) in renal and DOCA-induced hypertension in the rat by Eno AE1, Owo OI, Itam EH, Konya RS.(PubMed)
(3) The effect of nutrition on blood pressure by Savica V1, Bellinghieri G, Kopple JD(PubMed)

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