Tuesday, 3 October 2017

Food Therapy: Green Tea in Reduced Symptoms Severity and Treatment of Osteoarthritis

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Regular drinking of green tea may have a positive effect in reduced symptoms of pain and treatment of osteoarthritis, a study by respectable institute postulated.

Green tea, a precious drink processes numbers of health benefit known to almost everyone in Asia and Western world. However, as yin in nature herbal medicine ,or food, long term injection of large amounts may obstruct the balance of yin-yang, induced "yin excessive syndrome" or "yang vacuity syndrome" including weaken immunity and painful case of GERD,... according to traditional Chinese medicine's Yin-Yang theory. But a slice of ginger will neutralize that adverse effects.

Osteoarthritis (OA), a form of arthritis, is a condition characterized by aging progression of wear and tear on a joint, affecting over 25 million people in the United States in alone

In a randomized open-label active-controlled clinical trial of 50 adults with osteoarthritis of knee allocated to receive the green tea extract (in dosage form of tablet) plus diclofenac tablet as "intervention group"; or: diclofenac tablet alone as "control group" for a period of four weeks, combination treated group exerted a significant improvement of physical function in compared to control.

Treatment group also expressed a similar progress in pain reduction during knee joint physical function in adults with osteoarthritis as in control group.

Additionally, in the compared the effect of curcuminoids extract, hydrolyzed collagen and green tea extract, in chondrocytes culture cell, researchers  found that combination of all components score a enormous expression of reduced production of pro inflammatory cytokins through various mechanisms, including ameliorated free radical elucidation.

Furthermore, in the support of the above differentiation, the study in the investigation of a posttraumatic osteoarthritis (OA) mouse model tested with EGCG against progression of OA and relieve OA-associated pain, suggested that EGCG-treated mice promoted cartilage production against Safranin O, staining of the knee joint cartilage loss and cartilage erosion in compared to control group with no treatment.
Importantly, cartilage of treated mice also displays a significant reduction of gene in regulated degeneration of connective tissue as well as pathways involved promotional of tissues inflammation.

Additionally, pain score of treated mice also exhibited a significant enhancement in compared control group.

Taking together, there is no doubt that green tea process a therapeutic and integrated form for prevention and treatment of symptoms of pain as well as improved physical activity of OA patients through protection against cartilage degeneration.

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(1)Green tea (Camellia sinensis) for patients with knee osteoarthritis: A randomized open-label active-controlled clinical trial by Hashempur MH1, Sadrneshin S2, Mosavat SH3, Ashraf A4.(PubMed)
(2) Curcuminoids extract, hydrolyzed collagen and green tea extract synergically inhibit inflammatory and catabolic mediator's synthesis by normal bovine and osteoarthritic human chondrocytes in monolayer by Comblain F1, Sanchez C1, Lesponne I2, Balligand M3, Serisier S2, Henrotin Y4.(PubMed)
(3) Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model by Leong DJ, Choudhury M, Hanstein R, Hirsh DM, Kim SJ, Majeska RJ, Schaffler MB, Hardin JA, Spray DC, Goldring MB, Cobelli NJ, Sun HB.(PubMed)

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