In take of caffeinated coffee may have a reduced risk and treatment of Endometrial cancer, an Asian joint study supposed.
Coffee, becoming a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
Endometrial cancer is a medical condition characterized by cell growth disorderly and uncontrollably in the endometriosis. In the later stage, the cancer can spread to distant parts of tissues or organs.
In the review of published data of a total 1,534,039 participants from 13 published articles added in this meta-analysis, researchers found that reduced risk of endometrial cancers incidence is associated to coffee intake to patients never treated with any forms hormone therapies and either overweight or obese.
The relative odd ratio in these group of people were 0.66 and 0.77, respectively, correlated to decaffeinate and caffeine coffee intake.
In compared to decaffeinate coffee, caffeinated coffee showed a stronger in attenuated risk of 7% instead of 4% in decaffeinated intake,
The study also addressed that caffeine found in coffee may have a potential in enhanced coffee effects in ameliorated endometrial cancer expression. Risk of cancer is reduced by 4% for every 100mg caffeine intake per day.
1. Women drinking less than 4 cups of coffee per day were not associated with endometrial cancer risk.
2. Women drinking more than 4 cups coffee per day displayed a 25% decreased risk of endometrial cancer in compared to women who drank fewer that 1 cup per day.
Interestingly, the menopause women, the primary analyses included 45,696 women and 427 incident endometrial cancer cases, diagnosed over a total of 342,927 person-years of follow-up, suggested that
1. No association of endometrial cancer risk in coffee consumption in compared to non-daily drinkers (none or <1 cup/day),
2. Women who drank ≥4 cups/day have a relative odd ration of were 0.86. 0.63, for total coffee with 0.89 for caffeinated coffee, and 0.51 (95% CI 0.25, 1.03) for decaf coffee.
3. In obese women, compared to control group (none or <1 cup/day), women who drank ≥2 cups/day had a relative odd ratio of 0.72 for total coffee, 0.66 for caffeinated coffee. and 0.67 decaffeinated coffee drinkers.
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Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
(1) Coffee consumption and risk of endometrial cancer: a dose-response meta-analysis of prospective cohort studies by Zhou Q1, Luo ML2, Li H3, Li M4, Zhou JG5.(PubMed)
(2) A prospective cohort study of coffee consumption and risk of endometrial cancer over a 26-year follow-up by Je Y1, Hankinson SE, Tworoger SS, De Vivo I, Giovannucci E.(PubMed)