Food Therapy: Black Bean, Reduced Risk and Treatment of Colitis

Kyle J. Norton

People who turn to alternative medicine for treatment of disease in avoidance of adverse effects induced by conventional medicine should be patient. In compared to herbal medicine; food therapy even takes longer than six months to ease symptoms, depending to stages of the treatment which directly address to the cause of disease.

Black bean with abundant chemical constituents and fiber may be considered as function foods for prevention and treatment of colitis, a renowned institute indicated.

Colitis is medical condition of inflammation of the inner lining of the colon.

Black bean, a small roughly ovoid legume with glossy black shells, genus Phaseolus, belongings to the family Fabaceae can be bought in most grocery stores all around the year in dried and canned forms. It is believed that black bean was first domesticated growth in South America.

According to the joint study lead by the University of Guelph, in vivo, cooked whole-bean flours, with differing phenolic compound levels and profiles, showed a completed inhibition of colitis in a mouse model.

In C57BL/6 mice fed a 20 % navy bean or black bean flour-containing diet or an isoenergetic basal diet (BD) for 2 weeks before the induction of experimental colitis via 7 d dextran sodium sulphate (DSS, 2 % (w/v) in the drinking-water) exposure, coincidentally, both groups exerted similarly a beneficial and adverse effects in induced locally and systemically while aggravating colonic mucosal damage with unknown identity and systemic inflammation.

In bean treatment group, the efficacy in ameliorated colitis may be a result of the inhibition of pro inflammatory expression, such as colonic inflammatory cytokines (IL-6, IL-9, IFN-γ and IL-17A) and increased anti-inflammatory IL-10.

In mice with colon inflammation triggered by high-fat diet (HD)-induced obesity, injection of black bean expressed a significant decreased the concentrations of lipid and various circulating proinflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 in mice with HD-induced obesity, in attenuated change associated to colon inflammation.

Furthermore, mice treated with black bean also improved antioxidant status in reduced progression
of reactive oxygen species (ROS) in induction of oxidative stress.

Dr. Yook JS, the lead researchers said, "BAB ameliorates HD-induced disorders such as obesity and colitis by improving mucosal barrier protection and reducing endotoxemia, as well as by inactivating NF-κB to decrease the production of proinflammatory cytokines".

Taken together, black bean may be considered as a functional diet in reduced risk of colitis in high risk healthy subjects and treatment of patients with colitis with little or no adverse effects.

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Author Biography

Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Cooked navy and black bean diets improve biomarkers of colon health and reduce inflammation during colitis by Zhang C1, Monk JM1, Lu JT1, Zarepoor L1, Wu W1, Liu R1, Pauls KP2, Wood GA3, Robinson L4, Tsao R1, Power KA1.(PubMed)