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Bad news for coffee lovers, the recent study suggested that regular coffee consumptiontion may associate to increased risk of lung cancer.
Coffee, a popular and social beverage all over the world, particular in the West, is a drink made from roast bean from the Coffea plant, native to tropical Africa and Madagascar.
Lung cancer is a medical condition caused by irregular cell growth in the lung. At the later stage, cancer cells may spread to distant tissues and organs.
Dr. Wang Y, the lead author said, "a linear dose-response relationship exists between coffee consumption and risk of lung cancer".
1. Coffee high amount intake was associated to a significant positive lung cancer risk
2. Risk of lung cancer increased by 14% for additional 2 cups consumed daily.
Other, in the review of seventeen studies (5 cohort and 12 case-control studies) involving 12 276 cases and 102 516 controls met the predetermined inclusion criterion, extracted from data base of literature, the total risk of coffee intake and lung cancer incidence was 1.17 in compared to non drinkers. Also in compared to non drinkers, the relative risk of lung cancer was associated to numbers of cup per day consumed,
1. 1.10 (95% CI: 0.92-1.31) for ⩽1 cup per day,
2. 1.10 (95% CI: 0.93-1.30) for 2-3 cups per day and
3. 1.20 (95% CI: 1.02-1.39) for ⩾3 cups per day.
More importantly, Dr. Xie Y, the lead author said, " Significant associations for high coffee intake with increased risk of lung cancer were observed in men (OR=1.41 95% CI: 1.21-1.63), but not in women (OR=1.16, 95% CI: 0.86-1.56), in American (OR=1.34 95% CI: 1.08-1.65) and Asian populations (OR=1.49 95% CI: 1.28-1.74), but not in European populations (OR=1.12, 95% CI: 0.74-1.67), and in smokers (OR=1.24, 95% CI: 1.00-1.54), but not in nonsmokers (OR=0.85, 95% CI: 0.64-1.11)".
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(1) Coffee and tea consumption and risk of lung cancer: a dose-response analysis of observational studies by Wang Y, Yu X, Wu Y, Zhang D.(PubMed)
(2) Coffee consumption and risk of lung cancer: a meta-analysis by Tang N1, Wu Y, Ma J, Wang B, Yu R.(PubMed)