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Thursday, 2 January 2014

Food therapy - Strawberries and Lipid peroxidation

Strawberries
Strawberries is a genius of Fragaria × ananassa belongs to the family Roseaceae. They have been grown all over the world with suitable climate for commercial profits and for health benefits.
Beside cancer, heart disease kills more than 2,000 Americans everyday. Approximately 60 million Americans have heart disease.
Cholesterol is needed for our body to build cell walls, make hormones and vitamin D, and create bile salts that help you digest fat. However too much of it can be dangerous because cholesterol cannot dissolve in your blood. The special particle called lipoprotein moves this waxy, soft substance from place to place. If you have too much low density lipoprotein LDL that is known as bad cholesterol, overtime cholesterol can build up in your arterial walls causing blockage and leading to heart attack and stroke.
Lipid peroxidation is defined as a condition of oxidative degradation of lipids. 
 
Nutrients and Chemicals constituents
1. Carbohydrate
2. Dietary fiber
3. Omega 3 fatty acid
4. Calcium
5. Iron
6. Magnesium
7. Phosphorus
8. Potassium
9. Sodium
10. Zinc
11. Copper
12. Manganese
13. Selenium
14. Vitamin C
15. Thiamin
16. Niacin
17. Pantothenic acid
18. Vitamin B-6
19. Folate
20. Vitamin B-12
21. Vitamin A
22. Vitamin E
23. Vitamin K
24. Etc. 
The major chemical compounds include anthocyanin and ellagitannins and p-Hydroxybenzoic acid, p-coumaric acid, ellagic acid, cyanidin-3-glucoside, pelargonidin-3-glucoside, kaempferol, quercetin, and myricetin 
The Benefits
Strawberry chemical constituents are effective antioxidants and anti-inflammatory agents in reducing cardiovascular disease risk factors. In the testing of tested the hypothesis of freeze-dried strawberry powder (FSP) will lower fasting lipids and biomarkers of oxidative stress and inflammation at four weeks compared to baseline, total cholesterol and LDL-cholesterol levels and lipid peroxidation in the form of malondialdehyde and hydroxynonenal (-14%, p < 0.01)were significantly lower at 4 weeks versus baseline. Others in the study of fruit extract of three strawberry cultivars also found the similar result as strawberry fruit that has a scavenging effect against the radicals prevents that lipid peroxidation in in vitro environment. In cooked chicken patties, SE also acted as an effective antioxidant and suppressed lipid peroxidation.
The Side effects 
1. Some people may be experience anaphylactoid reaction to the consumption of strawberries
2. Oxalation
Oxalates in high concentration can cause problem for people with kidney diseases.
3. Etc.

Reference
(1) The strawberry: composition, nutritional quality, and impact on human health. by Giampieri F, Tulipani S, Alvarez-Suarez JM, Quiles JL, Mezzetti B, Battino M.(PubMed)
(2) Phenolic Composition of Strawberry Genotypes at Different Maturation Stages(ACS Publication)
(3) Freeze-dried strawberry powder improves lipid profile and lipid peroxidation in women with metabolic syndrome: baseline and post intervention effects. by Basu A, Wilkinson M, Penugonda K, Simmons B, Betts NM, Lyons TJ.(PubMed)
(4) The fruit extract of three strawberry cultivars prevents lipid peroxidation and protects the unsaturated fatty acids in the Fenton reagent environment. by Ozsahin AD, Gokce Z, Yilmaz O, Kirecci OA.(PubMed)
(5) Response surface optimisation of extraction of antioxidants from strawberry fruit, and lipid peroxidation inhibitory potential of the fruit extract in cooked chicken patties.
Saha J, Debnath M, Saha A, Ghosh T, Sarkar PK.(PubMed)