Researchers may have found a natural whole food for the treatment of oxidative stress-related diseases with no side effects, according to the studies.
Oxidative stress is a result of long-term overexpression of free radical compared to the levels of antioxidants.
In other words, depletion of antioxidant enzymes produced by the body is no longer can perform the function of neutralizing the free radical expression.
Free radicals are unstable atoms which have an unpaired electron on the outer ring. Therefore, in order to maintain stable, free radicals must donate or intercept an electron from other atoms, causing the domino's reaction that can not be stopped until all single electrons are paired or inhibited by antioxidants.
Antioxidants are stable atoms which inhibit oxidation.
Oxidative stress has been found to induced protein, lipid and alternation of cellular DNA, leading to the incidence of chronic illness and cancers.
Futhermore, although free radicals are a normal byproduct of oxygen metabolism, certain environmental and behavioral factors such as exposure to radiation and toxic chemicals and smoking can dramatically increase the number of free radicals in the body.
Some researchers suggested, maintaining a balanced ratio free radicals and antioxidants are the best way for good health.
Dr. V. Lobo, the lead scientist in the evaluation of the free radicals and antioxidants wrote, " A balance between free radicals and antioxidants is necessary for proper physiological function. If free radicals overwhelm the body's ability to regulate them, a condition known as oxidative stress ensues. Free radicals thus adversely alter lipids, proteins, and DNA and trigger a number of human diseases".
Scientists with an aim to find a natural remedy for the treatment of diseases associated with oxidative stress investigated the bilberry antioxidant activity in an animal model.
Selected rats were divided into 4 groups: control, rats treated with only gentamicin, with only bilberry, and treated with both gentamicin and bilberry.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Bilberry: Chemical Profiling, in Vitro and in Vivo Antioxidant Activity and Nephroprotective Effect against Gentamicin Toxicity in Rats by Veljković M1, Pavlović DR2, Stojiljković N1, Ilić S1, Jovanović I3, Poklar Ulrih N4, Rakić V5, Veličković L6, Sokolović D. (PubMed)
(2) Antioxidant and proapoptotic effects of anthocyanins from bilberry extract in rats exposed to hepatotoxic effects of carbon tetrachloride by Popović D1, Đukić D2, Katić V3, Jović Z4, Jović M5, Lalić J6, Golubović I7, Stojanović S8, Ulrih NP9, Stanković M10, Sokolović D. (PubMed)
(3) Free radicals, antioxidants, and functional foods: Impact on human health by V. Lobo, A. Patil, A. Phatak, and N. Chandra. (PubMed)