Macular degeneration is a condition caused by the blurring of the center of the vision without affecting the side or peripheral vision.
Age-related macular degeneration (AMD) is an aging process found in older adults is the leading cause of blindness in adults over the age of 55.
* The dry form is a milder form found in most patients with AMD with gradual degeneration of the central retinal tissues that make up the macula.
and often in the greenhouse.
With an aim to find a natural treatment of eye disease, researchers examined the combinations of antioxidants including lutein+zeaxanthin (1 μM; 0.2 μM), zinc (10 µM), carnosic acid (2 µM), beta-carotene (2 µM), and standardized tomato extract containing lycopene and other tomato phytonutrients added to the culture media.against age-related macular degeneration (AMD).
The results of the effects were attributed to the upregulation of antioxidative genes (HMOX1, SOD1) expression and the inhibition of pro-angiogenic genes and pro-inflammatory genes (SDF-1, TNF-alpha, IL-6, MCP-1).
Futhermore, in oxidative stress-induced damage to the retinal pigment epithelial (RPE) on age-related macular degeneration and neovascular retinopathies (e.g., retinopathy of prematurity, diabetic retinopathy, researchers investigated xanthophyll carotenoids, lutein, and zeaxanthin, isolated from toma in damage of retinal pigment epithelial (RPE) cells.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Characterizing the effect of supplements on the phenotype of cultured macrophages from patients with age-related macular degeneration by Rinsky B1, Hagbi-Levi S1, Elbaz-Hayoun S1, Grunin M1, Chowers. (PubMed)
(2) Effects of the Macular Carotenoid Lutein in Human Retinal Pigment Epithelial Cells by Gong X1, Draper CS2, Allison GS3, Marisiddaiah R4, Rubin LP. (PubMed)
(3) Smoking and Age-Related Macular Degeneration: Review and Update by Sara Velilla, 1 , 2 José Javier García-Medina, 3 , 4 , 5 Alfredo García-Layana, 2 , 6Rosa Dolz-Marco, 5 , 7 Sheila Pons-Vázquez, 5 M. Dolores Pinazo-Durán, 2 , 5 , 8Francisco Gómez-Ulla, 2 , 9 , 10 J. Fernando Arévalo, 11 , 12 Manuel Díaz-Llopis, 2 , 7 , 8 and Roberto Gallego-Pinazo. (PMC)