Hepatotoxicity is a condition caused by the accumulation of toxin in the liver, leading to liver dysfunction or reduced liver function.
Acute liver toxicity is caused by short-term exposure to toxic chemicals such as overdose of medication.
Chronic liver toxicity is due to long-term exposure to toxic substances including excessive alcohol drinking and long term use of certain medicines.
In other words, if the liver was damaged due to toxicity, the blood will be toxic, affecting the function of all organs and tissues in the body.
Epidemiological studies suggested liver dysfunction can also induce acute kidney injury (AKI), chronic kidney disease, linked to the increased mortality, extending to those with chronic liver disease.
There are many causes associated with liver toxicity including chemicals toxins, which normally induces acute liver toxicity, such as those used in laboratories and industries, natural chemicals and long-term use of certain medication.
In the Western world, acute and chronic liver toxicity mostly are caused by long-term excessive alcohol drinking and long-term use of medication in the elderly.
Most common signs and symptoms of liver toxicity may include jaundice, abdominal pain, gastrointestinal discomforts, fatigue, Stomach pain. Nausea (upset stomach) Unusual tiredness. dark-colored urine, and pale-colored bowel movements.
If you are experiencing some of the above signs and symptoms, please check with your doctor to rule the possibility of liver toxicity.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Scientists in finding a natural compound for the treatment of liver dysfunction investigated the ginger effect against Aflatoxin B1 (AFB1) induced liver toxicity.
Furthermore, injection of GE showed the significant hepatoprotective effect by reducing not only the lipid peroxidation but also by enhancing the antioxidant enzymes produced by the host of tested animals.
Patients selected to the study were divided into the ginger and placebo groups (30 patients in each group). Patient in each group was given either 500 mg ginger (Zintoma)(®) or placebo one-half hour before each daily dose of antituberculosis drugs for 4 weeks.
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Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
(1) Protective effects of phenolics rich extract of ginger against Aflatoxin B1-induced oxidative stress and hepatotoxicity by A V V1, K RR1, Kurrey NK2, K A AA1, G V3. (PubMed)
(2) Ginger for Prevention of Antituberculosis-induced Gastrointestinal Adverse Reactions Including Hepatotoxicity: A Randomized Pilot Clinical Trial by Emrani Z1, Shojaei E2, Khalili H. (PubMed)