Friday, 15 March 2019

Fermented Cucumbers (Cucumis sativus), the Natural Probiotics to Human Health

By Kyle J. Norton

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Probiotics are live bacteria and yeasts that play an essential role in the improvement of digestive functioning.

In other words, probiotics balanced the ratio of the gut microbiota by improving the levels of healthy organisms in the gut, particularly in people who are taking antibiotics, leading to the optimization of the digestive system in the absorption nutrients for the body needs such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function.

Where gut microbiota is the complex community of microorganisms that live in our gastrointestinal tracts.

Microbial imbalance or dysbiosis induced intestinal inflammation as a result of overexpression of bad organisms in the gut has been found to utilize a complex arsenal of virulence factors to colonize and persist in the intestine, implicating the development of intestinal diseases. 

Some virulence factors such as the genotoxin colibactin, produced by overexpression of bad bacteria in the gut were found to promote colorectal cancer and chronic intestinal inflammatory diseases.

Dr, Yu-Jie Zhang, the lead scientists in the examined the importance of gut bacteria on Human Health wrote, "Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells".

And, " they (imbalanced ratio of gut microbiota) can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism".

Cucumber plant is a species of Cucumis Sativus, belongs to the family Cucurbitaceae and native to Western Asia. It is a creeping vine with roots in the ground and grows up with the support of frames.

With an aim to find potential and natural compound for the improvement of digestive health, researchers investigation the probiotic activity of cucumber.

According to the novel strain of lactic acid bacterium isolated from fermented cucumber, the ferment carbohydrates such as sucrose, dextrose, and arabinose showed a significant gastroprotective effect against antibiotics, including ciprofloxacin, kanamycin, vancomycin.

Furthermore, the isolate displayed potential probiotic properties in the improvement of the digestive health observed by hydrophobicity, autoaggregation, coaggregation, and in vitro cell adhesion ability.

Moreover, the isolate also exhibited resistance against bad bacteria and simulated gastric juice at pH 3.0.

Based on the findings researchers suggested that novel strain of lactic acid bacterium isolated from fermented cucumber protected the digestive tract against the injection of antibiotics, inhibited the production of bad bacteria such as gram-positive bacterial and utilized the effects of prebiotics such as inulin and raffinose.

Dr. Shukla R, the lead scientist said, " These results indicate both probiotic property and the glucansucrase-producing ability of P. pentosaceus CRAG3".

In vitro, in the evaluation of the probiotic potentials of three Bacillus strains 437F, 1630F and 1020G obtained from the traditional pickle researchers found that
* All strains only showed high acid, bile tolerance but also exhibited antagonistic activity against various pathogens. 

* All strains exhibited antioxidant activity, auto- and co-aggregation ability and surface hydrophobicity and attachment capacity against the Caco-2 cells were similar to those of well-known probiotic strains.

* All strains are safe without causing harm to healthy colon cells.

Based on the findings, researchers said, "With respect to their characteristics and safety aspect, these Bacillus species may have potential to consider as probiotics for animal and/or human applications".

Taken altogether, cucumber may be considered supplements for the protection of digestive functioning, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

(1) Probiotic Potential of Pediococcus pentosaceus CRAG3: A New Isolate from Fermented Cucumber by Shukla R1, Goyal A. (PubMed)
(2) Three novel Bacillus strains from a traditional lacto-fermented pickle as potential probiotics by Talebi S1, Makhdoumi A1, Bahreini M1, Matin MM1,2, Moradi HS. (PubMed)
(3) Impacts of Gut Bacteria on Human Health and Diseases by Yu-Jie Zhang,1 Sha Li,2 Ren-You Gan,3 Tong Zhou,1 Dong-Ping Xu,1 and Hua-Bin Li1. (PubMed)

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